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  1. The unmitigated profile of COVID-19 infectiousness

    This article has 6 authors:
    1. Ron Sender
    2. Yinon Bar-On
    3. Sang Woo Park
    4. Elad Noor
    5. Jonathan Dushoff
    6. Ron Milo
    This article has been curated by 1 group:
    • Curated by eLife

      Evaluation Summary:

      A pathogen's generation interval directly affects estimates of its transmissibility (R), and the period of self-isolation or quarantine needed to prevent transmission. This study shows that the unmitigated generation interval of the original variant of SARS-CoV-2 is several days longer than previously estimated and that interventions have substantially decreased the effective generation interval. These findings improve our ability to model counterfactual intervention-free scenarios. Overall technically sound analyses support the conclusions, and extensive sensitivity analyses show that the findings are robust. However, sampling or ascertainment bias in this relatively small pre-intervention dataset or biased inputs could affect the accuracy of the reported estimates.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #3 agreed to share their name with the authors.)

    Reviewed by eLife, ScreenIT

    This article has 6 evaluationsAppears in 2 listsLatest version Latest activity
  2. Germinal centre-driven maturation of B cell response to SARS-CoV-2 vaccination

    This article has 21 authors:
    1. Wooseob Kim
    2. Julian Q. Zhou
    3. Alexandria J. Sturtz
    4. Stephen C. Horvath
    5. Aaron J. Schmitz
    6. Tingting Lei
    7. Elizaveta Kalaidina
    8. Mahima Thapa
    9. Wafaa B. Alsoussi
    10. Alem Haile
    11. Michael K. Klebert
    12. Teresa Suessen
    13. Luis Parra-Rodriguez
    14. Philip A. Mudd
    15. William D. Middleton
    16. Sharlene A. Teefey
    17. Iskra Pusic
    18. Jane A. O’Halloran
    19. Rachel M. Presti
    20. Jackson S. Turner
    21. Ali H. Ellebedy

    Reviewed by ScreenIT

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  3. Multiple spillovers from humans and onward transmission of SARS-CoV-2 in white-tailed deer

    This article has 18 authors:
    1. Suresh V. Kuchipudi
    2. Meera Surendran-Nair
    3. Rachel M. Ruden
    4. Michele Yon
    5. Ruth H. Nissly
    6. Kurt J. Vandegrift
    7. Rahul K. Nelli
    8. Lingling Li
    9. Bhushan M. Jayarao
    10. Costas D. Maranas
    11. Nicole Levine
    12. Katriina Willgert
    13. Andrew J. K. Conlan
    14. Randall J. Olsen
    15. James J. Davis
    16. James M. Musser
    17. Peter J. Hudson
    18. Vivek Kapur

    Reviewed by ScreenIT

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  4. Modelling the response to vaccine in non-human primates to define SARS-CoV-2 mechanistic correlates of protection

    This article has 23 authors:
    1. Marie Alexandre
    2. Romain Marlin
    3. Mélanie Prague
    4. Severin Coleon
    5. Nidhal Kahlaoui
    6. Sylvain Cardinaud
    7. Thibaut Naninck
    8. Benoit Delache
    9. Mathieu Surenaud
    10. Mathilde Galhaut
    11. Nathalie Dereuddre-Bosquet
    12. Mariangela Cavarelli
    13. Pauline Maisonnasse
    14. Mireille Centlivre
    15. Christine Lacabaratz
    16. Aurelie Wiedemann
    17. Sandra Zurawski
    18. Gerard Zurawski
    19. Olivier Schwartz
    20. Rogier W Sanders
    21. Roger Le Grand
    22. Yves Levy
    23. Rodolphe Thiébaut
    This article has been curated by 1 group:
    • Curated by eLife

      Evaluation Summary:

      This work should be of interest to a broad readership in infectious diseases, especially those people interested in modeling of infections. It combines statistical and mechanistic modeling to find assayable correlates of immunity for vaccines. This method could be relevant to many diseases or vaccines, although the particular markers identified here likely will be limited in their generalizability.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

    Reviewed by eLife, ScreenIT

    This article has 6 evaluationsAppears in 2 listsLatest version Latest activity
  5. Microglia Do Not Restrict SARS-CoV-2 Replication following Infection of the Central Nervous System of K18-Human ACE2 Transgenic Mice

    This article has 18 authors:
    1. Gema M. Olivarria
    2. Yuting Cheng
    3. Susana Furman
    4. Collin Pachow
    5. Lindsay A. Hohsfield
    6. Charlene Smith-Geater
    7. Ricardo Miramontes
    8. Jie Wu
    9. Mara S. Burns
    10. Kate I. Tsourmas
    11. Jennifer Stocksdale
    12. Cynthia Manlapaz
    13. William H. Yong
    14. John Teijaro
    15. Robert Edwards
    16. Kim N. Green
    17. Leslie M. Thompson
    18. Thomas E. Lane

    Reviewed by ScreenIT

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  6. Long-read 16S-seq reveals nasopharynx microbial dysbiosis and enrichment of Mycobacterium and Mycoplasma in COVID-19 patients: a potential source of co-infection

    This article has 22 authors:
    1. Punit Prasad
    2. Soumendu Mahapatra
    3. Rasmita Mishra
    4. Krushna Chandra Murmu
    5. Shifu Aggarwal
    6. Manisha Sethi
    7. Priyanka Mohapatra
    8. Arup Ghosh
    9. Rina Yadav
    10. Hiren Dodia
    11. Shamima Azma Ansari
    12. Saikat De
    13. Deepak Singh
    14. Amol Suryawanshi
    15. Rupesh Dash
    16. Shantibhushan Senapati
    17. Tushar K. Beuria
    18. Soma Chattopadhyay
    19. Gulam Hussain Syed
    20. Rajeeb Swain
    21. Sunil K. Raghav
    22. Ajay Parida

    Reviewed by ScreenIT

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  7. Maternal immune response and placental antibody transfer after COVID-19 vaccination across trimester and platforms

    This article has 24 authors:
    1. Caroline G. Atyeo
    2. Lydia L. Shook
    3. Sara Brigida
    4. Rose M. De Guzman
    5. Stepan Demidkin
    6. Cordelia Muir
    7. Babatunde Akinwunmi
    8. Arantxa Medina Baez
    9. Maegan L. Sheehan
    10. Erin McSweeney
    11. Madeleine D. Burns
    12. Ruhi Nayak
    13. Maya K. Kumar
    14. Chinmay D. Patel
    15. Allison Fialkowski
    16. Dana Cvrk
    17. Ilona T. Goldfarb
    18. Lael M. Yonker
    19. Alessio Fasano
    20. Alejandro B. Balazs
    21. Michal A. Elovitz
    22. Kathryn J. Gray
    23. Galit Alter
    24. Andrea G. Edlow

    Reviewed by Rapid Reviews Infectious Diseases, ScreenIT

    This article has 3 evaluationsAppears in 2 listsLatest version Latest activity
  8. Impact of the COVID-19 pandemic on routine surveillance for adults with chronic hepatitis B virus (HBV) infection in the UK

    This article has 34 authors:
    1. Cori Campbell
    2. Tingyan Wang
    3. David A. Smith
    4. Oliver Freeman
    5. Theresa Noble
    6. Kinga A Várnai
    7. Steve Harris
    8. Hizni Salih
    9. Gail Roadknight
    10. Stephanie Little
    11. Ben Glampson
    12. Luca Mercuri
    13. Dimitri Papadimitriou
    14. Christopher R Jones
    15. Vince Taylor
    16. Afzal Chaudhry
    17. Hang Phan
    18. Florina Borca
    19. Josune Olza
    20. Frazer Warricker
    21. Luis RomĂŁo
    22. David Ramlakhan
    23. Louise English
    24. Paul Klenerman
    25. Monique I. Andersson
    26. Jane Collier
    27. Eleni Nastouli
    28. Salim I. Khakoo
    29. William Gelson
    30. Graham S. Cooke
    31. Kerrie Woods
    32. Jim Davies
    33. Eleanor Barnes
    34. Philippa C. Matthews

    Reviewed by ScreenIT

    This article has 1 evaluationAppears in 1 listLatest version Latest activity