Evaluated articles

Essential Roles of RodA Peptidoglycan Polymerase and PBP2 Transpeptidase in Expression of Cell Wall-Spanning Supramolecular Organelles and Modulating Salmonella Virulence

1. Anne C. Doble
2. Bethany C Gollan
3. John Clark-Corrigall
4. David M. Bulmer
5. Richard A Daniel
6. Pietro Mastroeni
7. C. M. Anjam Khan

Reviewed by Arcadia Science

The actomyosin system is essential for the integrity of the endosomal system in bloodstream form Trypanosoma brucei

1. Fabian Link
2. Sisco Jung
3. Xenia Malzer
4. Felix Zierhut
5. Antonia Konle
6. Alyssa Borges
7. Christopher Batters
8. Monika Weiland
9. Mara Pöllmann
10. An Binh Nguyen
11. Johannes Kullmann
12. Claudia Veigel
13. Markus Engstler
14. Brooke Morriswood

• Curated by eLife

  eLife assessment

  This important study builds on a previous publication (with partially overlapping authors), demonstrating that T. brucei has a continuous endomembrane system, which probably facilitates high rates of endocytosis. Using a range of cutting-edge approaches, the authors present compelling evidence that an actomyosin system, with the myosin TbMyo1 as the molecular motor, is localized close to the endosomal system in the bloodstream form (BSF) of Trypanosoma brucei. It shows convincingly that actin plays a role in the organization and integrity of the endosomal system, and that the trypanosome Myo1is an active motor that interacts with actin and transiently associates with endosomes, but a role of Myo1 in endomembrane function in vivo was not directly demonstrated. This work should be of interest to cell biologists and microbiologists working on the cytoskeleton, and unicellular eukaryotes.

Reviewed by Arcadia Science, eLife

Estimates of molecular convergence reveal pleiotropic genes underlying adaptive variation across teleost fish

1. Agneesh Barua
2. Brice Beinsteiner
3. Vincent Laudet
4. Marc Robinson-Rechavi

Reviewed by Arcadia Science

ESPRESSO: Spatiotemporal omics based on organelle phenotyping

1. Lorenzo Scipioni
2. Giulia Tedeschi
3. Mariana Navarro
4. Yunlong Jia
5. Scott Atwood
6. Jennifer A. Prescher
7. Michelle Digman

Reviewed by Arcadia Science

Shotgun metagenomic analysis of the skin mucus bacteriome of the common carp ( Cyprinus carpio )

1. Márton Papp
2. Adrienn Gréta Tóth
3. Sára Ágnes Nagy
4. Károly Erdélyi
5. Gergely Maróti
6. Niamh Cox
7. László Czikk
8. Máté Katics
9. László Békési
10. Norbert Solymosi

Reviewed by PREreview, Arcadia Science

Time-resolved mitochondrial-focused screening identifies regulatory components of oxidative metabolism

1. Marcos Zamora-Dorta
2. Sara Laine-Menéndez
3. David Abia
4. Pilar González-García
5. Luis C. López
6. Paula Fernández-Montes Díaz
7. Enrique Calvo
8. Jesús Vázquez
9. José Antonio Enríquez
10. Eduardo Balsa

Reviewed by Arcadia Science

The retrotransposon - derived capsid genes PNMA1 and PNMA4 maintain reproductive capacity

1. Thomas W.P. Wood
2. William S. Henriques
3. Harrison B. Cullen
4. Mayra Romero
5. Cecilia S. Blengini
6. Shreya Sarathy
7. Julia Sorkin
8. Hilina Bekele
9. Chen Jin
10. Seungsoo Kim
11. Alexei Chemiakine
12. Rishad C. Khondker
13. José V.V. Isola
14. Michael B. Stout
15. Vincenzo A. Gennarino
16. Binyam Mogessie
17. Devanshi Jain
18. Karen Schindler
19. Yousin Suh
20. Blake Wiedenheft
21. Luke E. Berchowitz

Reviewed by Arcadia Science

A Blueprint for Broadly Effective Bacteriophage Therapy Against Bacterial Infections

1. Minyoung Kevin Kim
2. Qingquan Chen
3. Arne Echterhof
4. Robert C. McBride
5. Nina Pennetzdorfer
6. Niaz Banaei
7. Elizabeth B. Burgener
8. Carlos E. Milla
9. Paul L. Bollyky

Reviewed by Arcadia Science, PREreview

PBP4 is required for serum-induced cell wall thickening and antibiotic tolerance in Staphylococcus aureus

1. Elizabeth V. K. Ledger
2. Ruth C. Massey

Reviewed by Arcadia Science

An algicidal bacterium shapes the microbiome during outdoor diatom cultivation collapse

1. Naomi E. Gilbert
2. Jeffery A. Kimbrel
3. Ty J. Samo
4. Anthony J. Siccardi
5. Rhona K. Stuart
6. Xavier Mayali

Reviewed by Arcadia Science

Compartmentalized Cytoplasmic Flows Direct Protein Transport to the Cell’s Leading Edge

1. Catherine G. Galbraith
2. Brian P. English
3. Ulrike Boehm
4. James A. Galbraith

Reviewed by Arcadia Science

Laboratory horror stories: Poison in the agars

1. Mari K. Davidson
2. Reine U. Protacio
3. Dominique Helmlinger
4. Wayne P. Wahls

Reviewed by Arcadia Science

Robust virtual staining of landmark organelles

1. Ziwen Liu
2. Eduardo Hirata-Miyasaki
3. Soorya Pradeep
4. Johanna Rahm
5. Christian Foley
6. Talon Chandler
7. Ivan Ivanov
8. Hunter Woosley
9. Tiger Lao
10. Akilandeswari Balasubramanian
11. Chad Liu
12. Manu Leonetti
13. Carolina Arias
14. Adrian Jacobo
15. Shalin B. Mehta

Reviewed by Arcadia Science

Prediction of anti-freezing proteins from their evolutionary profile

1. Nishant Kumar
2. Shubham Choudhury
3. Nisha Bajiya
4. Sumeet Patiyal
5. Gajendra P. S. Raghava

Reviewed by Arcadia Science

GTalign: High-performance protein structure alignment, superposition, and search

1. Mindaugas Margelevičius

Reviewed by Arcadia Science

The bacterial microbiome of symbiotic and menthol-bleached polyps of long-term aquarium-reared Galaxea fascicularis

1. Giulia Puntin
2. Jane C. Y. Wong
3. Till Röthig
4. David M. Baker
5. Michael Sweet
6. Maren Ziegler

Reviewed by Arcadia Science

DNA binding is rate-limiting for natural transformation

1. Taylor J. Ellison
2. Courtney K. Ellison

Reviewed by Arcadia Science

Insights into Immune Gene Prediction and Function Through the Evolutionary History of ADF Gene Family

1. Huan Chen
2. Brad Day

Reviewed by Arcadia Science

Activity-dependent FosB gene expression negatively regulates mast cell functions

1. Natalia Duque-Wilckens
2. Nidia Maradiaga
3. Yeh Szu-Ying
4. Dimitry Joseph
5. Vidhula Srinavasan
6. Kyan Thelen
7. Fabiola Sotomayor
8. Kait Durga
9. Eric Nestler
10. Adam J Moeser
11. A.J. Robison

Reviewed by Arcadia Science

Molecular Display of the Animal Meta-Venome for Discovery of Novel Therapeutic Peptides

1. Meng-Hsuan Hsiao
2. Yang Miao
3. Zixing Liu
4. Konstantin Schütze
5. Nathachit Limjunyawong
6. Daphne Chun-Che Chien
7. Wayne Denis Monteiro
8. Lee-Shin Chu
9. William Morgenlander
10. Sahana Jayaraman
11. Sung-eun Jang
12. Jeffrey J. Gray
13. Heng Zhu
14. Xinzhong Dong
15. Martin Steinegger
16. H. Benjamin Larman

Reviewed by Arcadia Science