Latest preprint reviews

1. Immunosuppression Drugs Exhibit Differential Effects on Endothelial Cell Function

   This article has 7 authors:

   1. Aly Elezaby
   2. Ryan Dexheimer
   3. David Wu
   4. Sze Yu Chan
   5. Ian Y. Chen
   6. Nazish Sayed
   7. Karim Sallam

   Reviewed by PREreview

2. Fluorescent Antibody-Based Detection and Ultrastructural Analysis of Streptococcus pneumoniae in Human Sputum

   This article has 10 authors:

   1. Ana G. Jop Vidal
   2. Meg Francis
   3. Maneesha Chitanvis
   4. Ithiel J. Frame
   5. Poonam Sharma
   6. Patricio Vidal
   7. Claudio F. Lanata
   8. Carlos Grijalva
   9. William Daley
   10. Jorge E. Vidal

   Reviewed by PREreview

3. Stress from Cadaver Dissection Linked to Learning Conditions: Evidence from Sub-Saharan Africa

   This article has 4 authors:

   1. Jude Amechi Nnaka
   2. Victor Udochukwu Ezeike
   3. Kristjan Thompson
   4. Izuchukwu Azuka Okafor

   Reviewed by PREreview

4. Safety and efficacy of the blood-stage malaria vaccine RH5.1/Matrix-M in Burkina Faso: interim results of a double-blind, randomised, controlled phase 2b trial in children

   This article has 32 authors:

   1. Hamtandi M. Natama
   2. Jo Salkeld
   3. Athanase Somé
   4. Seyi Soremekun
   5. Salou Diallo
   6. Ousmane Traoré
   7. Toussaint Rouamba
   8. Florence Ouédraogo
   9. Edouard Ouédraogo
   10. K. Carine Sonia Daboné
   11. Nadine A. Koné
   12. Z. Michael John Compaoré
   13. Miguel Kafando
   14. Massa dit Achille Bonko
   15. Fabé Konaté
   16. Hermann Sorgho
   17. Carolyn M. Nielsen
   18. Dimitra Pipini
   19. Ababacar Diouf
   20. Lloyd D. W. King
   21. Umesh Shaligram
   22. Carole A. Long
   23. Jee-Sun Cho
   24. Alison M. Lawrie
   25. Katherine Skinner
   26. Rachel Roberts
   27. Kazutoyo Miura
   28. John Bradley
   29. Sarah E. Silk
   30. Simon J. Draper
   31. Halidou Tinto
   32. Angela M. Minassian

   Reviewed by PREreview

5. Prior antiretroviral therapy exposure among clients presenting for HIV treatment initiation in South Africa: an exploratory mixed-methods study using multiple indicators of exposure

   This article has 9 authors:

   1. Mariet Benade
   2. Mhairi Maskew
   3. Vinolia Ntjikelane
   4. Nancy Scott
   5. Nkosinathi Ngcobo
   6. Brooke Nichols
   7. Lufuno Malala
   8. Musa Manganye
   9. Sydney Rosen

   Reviewed by PREreview

6. Toxoplasma Infection and Its Sequential Impact on Physical Health, Stress, and Anxiety: A Large Cross-Sectional Study Testing the Stress-Coping Hypothesis

   This article has 3 authors:

   1. Jaroslav Flegr
   2. Ashkan Latifi
   3. Šárka Kaňková

   Reviewed by PREreview

7. IMPACTO SOCIAL DE LAS BARRERAS EN EL PROCESO DE CERTIFICACIÓN DE DISCAPACIDAD EN COLOMBIA

   This article has 3 authors:

   1. Lina María González Ballesteros
   2. Camila Andrea Castellanos Roncancio
   3. Jeimmi Paola Carvajal Guzmán

   Reviewed by PREreview

8. O ensino de Ciências no Brasil: Um olhar voltado à Educação Infantil e Séries Iniciais

   This article has 3 authors:

   1. Marluce da Cunha Mantovani
   2. Leandro Teodoro Júnior
   3. Mari Cleide Sogayar

   Reviewed by PREreview

9. Evaluación formativa: percepciones de los estudiantes de educación superior respecto a las habilidades/estrategias de aprendizaje autodirigido

   This article has 4 authors:

   1. Concepcion Elizabeth Marcillo-Garcia
   2. Elvira Geoconda Villacreses-Veliz
   3. Mercedes del Rosario Acuña-Acebo
   4. Jessenia Herminia Morán-Chilán

   Reviewed by PREreview

10. Large-scale characterization of drug mechanism of action using proteome-wide thermal shift assays

    This article has 8 authors:

    1. Jonathan G Van Vranken
    2. Jiaming Li
    3. Julian Mintseris
    4. Ting-Yu Wei
    5. Catherine M Sniezek
    6. Meagan Gadzuk-Shea
    7. Steven P Gygi
    8. Devin K Schweppe

    This article has been curated by 1 group:

    • Curated by eLife

      eLife Assessment

      The study provides a valuable showcase of a workflow to perform large-scale characterization of drug mechanisms of action using proteomics in which on-target and off-targets of 166 compounds using proteome solubility analysis in living cells and cell lysates were determined. The evidence supporting the claims of the authors is solid, however, the inclusion of more replicate experiments and more statistical rigor would have strengthened the study. This will be of broad interest to medicinal chemists, toxicologists, computational biologists and biochemists.

    Reviewed by PREreview, eLife