Evaluated articles

Bacterial Wastewater-Based Epidemiology Using Surface-Enhanced Raman Spectroscopy and Machine Learning

1. Liam K. Herndon
2. Yirui Zhang
3. Fareeha Safir
4. Babatunde Ogunlade
5. Halleh B. Balch
6. Alexandria B. Boehm
7. Jennifer A. Dionne

Reviewed by Arcadia Science

Have protein-ligand co-folding methods moved beyond memorisation?

1. Peter Škrinjar
2. Jérôme Eberhardt
3. Janani Durairaj
4. Torsten Schwede

Reviewed by Arcadia Science

Venomous Maggots? A first exploration of the toxin arsenal of larval stages of the horse fly Tabanus autumnalis

1. Jonas Krämer
2. Ludwig Dersch
3. Andreas Vilcinskas
4. Tim Lüddecke

Reviewed by Arcadia Science

Metagenomes and Metagenome-Assembled Genomes from Tidal Lagoons at a New York City Waterfront Park

1. Sally Kong
2. Eliana Abrams
3. Yehuda Binik
4. Christina Cappelli
5. Mathew Chu
6. Taiyo Cornett
7. Isayah Culbertson
8. Epifania Garcia
9. Jada Henry
10. Kristy Lam
11. DB Lampman
12. Grace Morenko
13. Illusion Rivera
14. Tanasia Swift
15. Isabella Torres
16. Rayven Velez
17. Elliot Waxman
18. Serena Wessely
19. Anthony Yuen
20. Casey K. Lardner
21. JL Weissman

Reviewed by Arcadia Science

AI.zymes – A modular platform for evolutionary enzyme design

1. Lucas Primus Merlicek
2. Jannik Neumann
3. Abbie Lear
4. Vivian Degiorgi
5. Moor de Waal
6. Tudor-Stefan Cotet
7. Adrian J. Mulholland
8. Hans Adrian Bunzel

Reviewed by Arcadia Science

In silico discovery of nanobody binders to a G-protein coupled receptor using AlphaFold-Multimer

1. Edward P. Harvey
2. Jeffrey S. Smith
3. Joseph D. Hurley
4. Alyana Granados
5. Ernst W. Schmid
6. Jason G. Liang-Lin
7. Steffanie Paul
8. Emily M. Meara
9. Matthew P. Ferguson
10. Victor G. Calvillo-Miranda
11. Debora S. Marks
12. Johannes C. Walter
13. Andrew C. Kruse
14. Katherine J. Susa

Reviewed by Arcadia Science

Amino acid repeat signatures underlying human-pathogen interactions

1. Anjali Kumari Singh
2. Nagashree Rachote
3. Anushka Agrawal
4. Vaidehi Sharma
5. Keertana Sai Kappagantula
6. Rajashekar Varma Kadumuri
7. Sreenivas Chavali

Reviewed by Arcadia Science

The Mp CAFA gene encodes a ciliary protein required for spermatozoid motility in the liverwort Marchantia polymorpha

1. Mizuki Morita
2. Katsuyuki T. Yamato

Reviewed by Arcadia Science

A conserved mechanism for the retrieval of polyubiquitinated proteins from cilia

1. Sven M. Lange
2. Robyn J. Eisert
3. Alan Brown

Reviewed by Arcadia Science

TRPV1+ neurons promote cutaneous immunity against Schistosoma mansoni

1. Juan M. Inclan-Rico
2. Adriana Stephenson
3. Camila M. Napuri
4. Heather L. Rossi
5. Li-Yin Hung
6. Christopher F. Pastore
7. Wenqin Luo
8. De’Broski R. Herbert

Reviewed by Arcadia Science

A low-cost FPGA-based approach for pile-up corrected high-speed in vivo FLIM imaging

1. Felipe Velasquez Moros
2. Dorian Amiet
3. Rachel Megan Meister
4. Alexandra von Faber-Castell
5. Matthias Wyss
6. Aiman S. Saab
7. Paul Zbinden
8. Bruno Weber
9. Luca Ravotto

Reviewed by Arcadia Science

Interleukin-27 is antiviral at the maternal-fetal interface

1. Madeline S. Merlino
2. Briah Barksdale
3. Seble G. Negatu
4. Rebecca L. Clements
5. Taylor Miller-Ensminger
6. Alexandra H. Lopez
7. Sneha Mani
8. Monica N. Mainigi
9. Christopher A. Hunter
10. Kellie A. Jurado

Reviewed by Arcadia Science

A Cross-Species Generative Cell Atlas Across 1.5 Billion Years of Evolution: The TranscriptFormer Single-cell Model

1. James D Pearce
2. Sara E Simmonds
3. Gita Mahmoudabadi
4. Lakshmi Krishnan
5. Giovanni Palla
6. Ana-Maria Istrate
7. Alexander Tarashansky
8. Benjamin Nelson
9. Omar Valenzuela
10. Donghui Li
11. Stephen R. Quake
12. Theofanis Karaletsos

Reviewed by Arcadia Science

Antibody affinity engineering using antibody repertoire data and machine learning

1. Lena Erlach
2. Simon Friedensohn
3. Daniel Neumeier
4. Derek M. Mason
5. Sai T. Reddy

Reviewed by Arcadia Science

Random UV Mutagenesis for the production of Chlorella vulgaris mutants with low chlorophyll content for the food industry

1. Ivan N. Ivanov
2. Jiří Kopecký
3. Karolína Štěrbová
4. Pavel Hrouzek
5. Martin Lukeš
6. Kateřina Bišová
7. Setyo Budi Kurniawan

Reviewed by Arcadia Science

The antifungal and other bioactive properties of the volatilome of Streptomyces scabiei

1. Nudzejma Stulanovic
2. Djulia Bensaada
3. Loïc Belde
4. Delphine Adam
5. Marc Hanikenne
6. Jean-François Focant
7. Pierre-Hugues Stefanuto
8. Sébastien Rigali

Reviewed by Arcadia Science

Eukaryotes’ closest relatives are internally simple syntrophic archaea

1. Hiroyuki Imachi
2. Masaru K. Nobu
3. Shun’ichi Ishii
4. Yuga Hirakata
5. Tetsuro Ikuta
6. Yuta Isaji
7. Makoto Miyata
8. Masayuki Miyazaki
9. Yuki Morono
10. Kazuyoshi Murata
11. Satoshi Nakagawa
12. Miyuki Ogawara
13. Satoshi Okada
14. Yumi Saito
15. Sanae Sakai
16. Shigeru Shimamura
17. Yuhei O. Tahara
18. Yoshihiro Takaki
19. Yoshinori Takano
20. Eiji Tasumi
21. Katsuyuki Uematsu
22. Toshihiro Yoshimura
23. Ken Takai

Reviewed by Arcadia Science

Stability vs flexibility: reshaping archaeal membranes in silico

1. Miguel Amaral
2. Felix Frey
3. Xiuyun Jiang
4. Buzz Baum
5. Anđela Šarić

• Curated by eLife

  eLife Assessment

  This important study characterizes the mechanics and stability of bolalipids from archaeal membranes using molecular dynamics simulations. A mesoscale model of bolalipids is presented and evaluated across a series of membrane configurations. The evidence supporting the conclusions is convincing, demonstrating that mixtures of bolalipids and regular bilayer lipids in archaeal membranes enhance fluidity and stability.

Reviewed by Arcadia Science, eLife

Toward De Novo Protein Design from Natural Language

1. Fengyuan Dai
2. Shiyang You
3. Chentong Wang
4. Yuliang Fan
5. Jin Su
6. Chenchen Han
7. Xibin Zhou
8. Jianming Liu
9. Hui Qian
10. Shunzhi Wang
11. Anping Zeng
12. Yajie Wang
13. Hongyuan Lu
14. Fajie Yuan

Reviewed by Arcadia Science

Varicose-projection astrocytes: a reactive phenotype associated with neuropathology

1. Caterina Ciani
2. Giulio Pistorio
3. Simona Giancola
4. Marika Mearelli
5. Francesca Emma Mongelli
6. Delaram Forouzeh
7. Luca Mio
8. Paula Ramos-Gonzalez
9. Carlos Matute
10. Ugne Kuliesiute
11. Sari Elena Dötterer
12. Gediminas Luksys
13. Saulius Rocka
14. Urte Neniskyte
15. Marya Ayub
16. Jean-Marie Graïc
17. Francesco Petrelli
18. Alexei Verkhratsky
19. Nunzio Iraci
20. Fabio Cavaliere
21. Carmen Falcone

Reviewed by Arcadia Science