Evaluated articles

Temporal constraints on enhancer usage shape the regulation of limb gene transcription

1. Raquel Rouco
2. Antonella Rauseo
3. Guillaume Sapin
4. Olimpia Bompadre
5. Fabrice Darbellay
6. Guillaume Andrey

Reviewed by preLights

OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide

1. Hugo Sepulveda
2. Xiang Li
3. Xiaojing Yue
4. J. Carlos Angel
5. Leo J. Arteaga-Vazquez
6. Caitlin Brown
7. Melina Brunelli
8. Natasha Jansz
9. Fabio Puddu
10. Jamie Scotcher
11. Páidí Creed
12. Patrick Kennedy
13. Cindy Manriquez
14. Samuel A Myers
15. Robert Crawford
16. Geoffrey J. Faulkner
17. Anjana Rao

Reviewed by preLights

Transcriptional profiling of human brain cortex identifies novel lncRNA-mediated networks dysregulated in amyotrophic lateral sclerosis

1. Alessandro Palma
2. Monica Ballarino

Reviewed by preLights

Structural basis of respiratory complexes adaptation to cold temperatures

1. Young-Cheul Shin
2. Pedro Latorre-Muro
3. Amina Djurabekova
4. Oleksii Zdorevskyi
5. Christopher F. Bennett
6. Nils Burger
7. Kangkang Song
8. Chen Xu
9. Vivek Sharma
10. Maofu Liao
11. Pere Puigserver

Reviewed by preLights

Clusters of lineage-specific genes are anchored by ZNF274 in repressive perinucleolar compartments

1. Martina Begnis
2. Julien Duc
3. Sandra Offner
4. Delphine Grun
5. Shaoline Sheppard
6. Olga Rosspopoff
7. Didier Trono

Reviewed by preLights

RIPK3 coordinates RHIM domain-dependent inflammatory transcription in neurons

1. Sigal B. Kofman
2. Lan H. Chu
3. Joshua M. Ames
4. Suny Dayane Chavarria
5. Katrina Lichauco
6. Brian P. Daniels
7. Andrew Oberst

Reviewed by preLights

Synergistic olfactory processing for social plasticity in desert locusts

1. Inga Petelski
2. Yannick Günzel
3. Sercan Sayin
4. Susanne Kraus
5. Einat Couzin-Fuchs

Reviewed by preLights

A long non-coding RNA at the cortex locus controls adaptive colouration in butterflies

1. Luca Livraghi
2. Joseph J. Hanly
3. Elizabeth Evans
4. Charlotte J. Wright
5. Ling S. Loh
6. Anyi Mazo-Vargas
7. Kiana Kamrava
8. Alexander Carter
9. Eva S.M. van der Heijden
10. Robert D. Reed
11. Riccardo Papa
12. Chris D. Jiggins
13. Arnaud Martin

Reviewed by preLights

Actin polymerization drives lumen formation in a human epiblast model

1. Dhiraj Indana
2. Andrei Zakharov
3. Youngbin Lim
4. Alexander R. Dunn
5. Nidhi Bhutani
6. Vivek B. Shenoy
7. Ovijit Chaudhuri

Reviewed by preLights

Plasmodium RON11 triggers biogenesis of the merozoite rhoptry pair and is essential for erythrocyte invasion

1. David Anaguano
2. Opeoluwa Adewale-Fasoro
3. Grace S. Vick
4. Sean Yanik
5. James Blauwkamp
6. Manuel A. Fierro
7. Sabrina Absalon
8. Prakash Srinivasan
9. Vasant Muralidharan

Reviewed by preLights

A complex Plasmodium falciparum cryptotype circulating at low frequency across the African continent

1. Olivo Miotto
2. Alfred Amambua-Ngwa
3. Lucas Amenga-Etego
4. Muzamil M Abdel Hamid
5. Ishag Adam
6. Enoch Aninagyei
7. Tobias Apinjoh
8. Gordon A Awandare
9. Philip Bejon
10. Gwladys I Bertin
11. Marielle Bouyou-Akotet
12. Antoine Claessens
13. David J Conway
14. Umberto D’Alessandro
15. Mahamadou Diakite
16. Abdoulaye Djimdé
17. Arjen M Dondorp
18. Patrick Duffy
19. Rick M Fairhurst
20. Caterina I Fanello
21. Anita Ghansah
22. Deus Ishengoma
23. Mara Lawniczak
24. Oumou Maïga-Ascofaré
25. Sarah Auburn
26. Anna Rosanas-Urgell
27. Varanya Wasakul
28. Nina FD White
29. Jacob Almagro-Garcia
30. Richard D Pearson
31. Sonia Goncalves
32. Cristina Ariani
33. Zbynek Bozdech
34. William Hamilton
35. Victoria Simpson
36. Dominic P Kwiatkowski

Reviewed by preLights

Spatial transcriptomics elucidates medulla niche supporting germinal center response in myasthenia gravis thymoma

1. Yoshiaki Yasumizu
2. Makoto Kinoshita
3. Martin Jinye Zhang
4. Daisuke Motooka
5. Koichiro Suzuki
6. Daisuke Okuzaki
7. Satoshi Nojima
8. Soichiro Funaki
9. Yasushi Shintani
10. Naganari Ohkura
11. Eiichi Morii
12. Tatsusada Okuno
13. Hideki Mochizuki

Reviewed by preLights

Holimap: an accurate and efficient method for solving stochastic gene network dynamics

1. Chen Jia
2. Ramon Grima

Reviewed by preLights

Unlocking the secrets of kangaroo locomotor energetics: Postural adaptations underpin increased tendon stress in hopping kangaroos

1. Lauren H. Thornton
2. Taylor J.M. Dick
3. John R. Hutchinson
4. Glen A. Lichtwark
5. Craig P. McGowan
6. Jonas Rubenson
7. Alexis Wiktorowicz-Conroy
8. Christofer J. Clemente

• Curated by eLife

  eLife assessment

  This valuable biomechanical analysis of kangaroo kinematics and kinetics across a range of hopping speeds and masses is a step towards understanding a long-standing problem in locomotion biomechanics: the mechanism for how, unlike other mammals, kangaroos are able to increase hopping speed without a concomitant increase in metabolic cost. Based on their suggestion that kangaroo posture changes with speed increase tendon stress/strain and hence elastic energy storage/return, the authors imply (but do not show quantitatively or qualitatively) that the greater tendon elastic energy storage/return counteracts the increased cost of generating muscular force at faster speeds and allows for the invariance in metabolic cost. The methods are impressive, but there is currently only limited evidence for increased tendon stress/strain at faster speeds, and the support for any conclusion metabolic energy expenditure is inadequate.

Reviewed by eLife, preLights

Aurora B controls microtubule stability to regulate abscission dynamics in stem cells

1. Snježana Kodba
2. Amber Öztop
3. Eri van Berkum
4. Malina K. Iwanski
5. Wilco Nijenhuis
6. Lukas C. Kapitein
7. Agathe Chaigne

Reviewed by preLights

Evolution of tandem repeats in putative CSP to enhance its function: A recent and exclusive event in Plasmodium vivax in India

1. Manoswini Dash
2. Veena Pande
3. Aparup Das
4. Abhinav Sinha

Reviewed by preLights

A tension-induced morphological transition shapes the avian extra-embryonic territory

1. Arthur Michaut
2. Alexander Chamolly
3. Aurélien Villedieu
4. Francis Corson
5. Jérôme Gros

Reviewed by preLights

A choroid plexus apocrine secretion mechanism shapes CSF proteome and embryonic brain development

1. Ya’el Courtney
2. Joshua P. Head
3. Elizabeth D. Yimer
4. Neil Dani
5. Frederick B. Shipley
6. Towia A. Libermann
7. Maria K. Lehtinen

Reviewed by preLights

A revised single-cell transcriptomic atlas of Xenopus embryo reveals new differentiation dynamics

1. Kseniya Petrova
2. Maksym Tretiakov
3. Aleksandr Kotov
4. Anne H. Monsoro-Burq
5. Leonid Peshkin

Reviewed by preLights

Epithelial Folding Irreversibility is Controlled by Elastoplastic Transition via Mechanosensitive Actin Bracket Formation

1. Aki Teranishi
2. Misato Mori
3. Rihoko Ichiki
4. Satoshi Toda
5. Go Shioi
6. Satoru Okuda

Reviewed by preLights