Evaluated articles

Classification of dinosaur footprints using machine learning

1. Michael Jones
2. Jens N. Lallensack
3. Ian Jarman
4. Peter Falkingham
5. Ivo Siekmann

Reviewed by preLights

Actin-based deformations of the nucleus control multiciliated ependymal cell differentiation

1. Marianne Basso
2. Alexia Mahuzier
3. Syed Kaabir Ali
4. Anaïs Marty
5. Marion Faucourt
6. Ana-Maria Lennon-Duménil
7. Ayush Srivastava
8. Michella Khoury Damaa
9. Alexia Bankole
10. Alice Meunier
11. Ayako Yamada
12. Julie Plastino
13. Nathalie Spassky
14. Nathalie Delgehyr

Reviewed by preLights, Arcadia Science

Torpor energetics are related to the interaction between body mass and climate in bats of the family Vespertilionidae

1. Jorge Ayala-Berdon
2. Kevin I. Medina-Bello

Reviewed by preLights

Long range mutual activation establishes Rho and Rac polarity during cell migration

1. Henry De Belly
2. Andreu Fernandez Gallen
3. Evelyn Strickland
4. Dorothy C. Estrada
5. Patrick J. Zager
6. Tamas L. Nagy
7. Janis K Burkhardt
8. Hervé Turlier
9. Orion D. Weiner

Reviewed by preLights

Intracellular diffusion in the cytoplasm increases with cell size in fission yeast

1. Catherine Tan
2. Michael C. Lanz
3. Matthew Swaffer
4. Jan Skotheim
5. Fred Chang

Reviewed by preLights

Deciphering the nanoscale architecture of presynaptic actin using a micropatterned presynapse-on-glass model

1. Sofia Tumminia
2. Louisa Mezache
3. Theresa Wiesner
4. Benoit Vianay
5. Manuel Théry
6. Marie-Jeanne Papandréou
7. Christophe Leterrier

Reviewed by preLights

Golgi compaction facilitates microtubule nucleation to drive adult vertebrate peripheral neuron regeneration

1. Alice E Mortimer
2. Adam J Reid
3. Raman M Das

Reviewed by preLights

Non-disruptive inducible labeling of ER-membrane contact sites using the Lamin B Receptor

1. Laura Downie
2. Nuria Ferrandiz
3. Megan Jones
4. Stephen J. Royle

Reviewed by preLights

HIF1A contributes to the survival of aneuploid and mosaic pre-implantation embryos

1. Estefania Sanchez-Vasquez
2. Marianne E Bronner
3. Magdalena Zernicka-Goetz

• Curated by eLife

  eLife Assessment

  Sanchez-Vasquez et al establish an innovative approach to induce aneuploidy in preimplantation embryos. This important study extends the author's previous publications evaluating the consequences of aneuploidy in the mammalian embryo. In this work, the authors investigate the developmental potential of aneuploid embryos and characterize changes in gene expression profiles under normoxic and hypoxic culture conditions. Using a solid methodology they identify sensitivity to Hif1alpha loss in aneuploid embryos, and in further convincing experiments they assess how levels of DNA damage and DNA repair are altered under hypoxic and normoxic conditions.

Reviewed by eLife, preLights

Global coordination of protrusive forces in migrating immune cells

1. Patricia Reis-Rodrigues
2. Nikola Canigova
3. Mario J. Avellaneda
4. Florian Gaertner
5. Kari Vaahtomeri
6. Michael Riedl
7. Jack Merrin
8. Robert Hauschild
9. Yoshinori Fukui
10. Alba Juanes Garcia
11. Michael Sixt

Reviewed by preLights

Axis reset is rate limiting for onset of whole-body regenerative abilities during planarian development

1. Clare L.T. Booth
2. Brian C. Stevens
3. Clover A. Stubbert
4. Neil T. Kallgren
5. Erin L. Davies

Reviewed by preLights

Multi-pass, single-molecule nanopore reading of long protein strands with single-amino acid sensitivity

1. Keisuke Motone
2. Daphne Kontogiorgos-Heintz
3. Jasmine Wee
4. Kyoko Kurihara
5. Sangbeom Yang
6. Gwendolin Roote
7. Yishu Fang
8. Nicolas Cardozo
9. Jeff Nivala

Reviewed by preLights

Mixed alkyl/aryl phosphonates identify metabolic serine hydrolases as antimalarial targets

1. John M. Bennett
2. Sunil K. Narwal
3. Stephanie Kabeche
4. Daniel Abegg
5. Vandana Thathy
6. Fiona Hackett
7. Tomas Yeo
8. Veronica L. Li
9. Ryan Muir
10. Franco Faucher
11. Scott Lovell
12. Michael J. Blackman
13. Alexander Adibekian
14. Ellen Yeh
15. David A. Fidock
16. Matthew Bogyo

Reviewed by preLights

Integrin conformation-dependent neutrophil slowing obstructs the capillaries of the pre-metastatic lung in a model of breast cancer

1. Frédéric Fercoq
2. Gemma S. Cairns
3. Marco De Donatis
4. John B. G. Mackey
5. Alessia Floerchinger
6. Amanda McFarlane
7. Ximena L. Raffo-Iraolagoitia
8. Declan Whyte
9. Lindsey W. G. Arnott
10. Colin Nixon
11. Robert Wiesheu
12. Anna Kilbey
13. Leah Brown
14. Sarwah Al-Khalidi
15. Jim C. Norman
16. Edward W. Roberts
17. Karen Blyth
18. Seth B. Coffelt
19. Leo M. Carlin

Reviewed by preLights

An updated and expanded characterization of the biological sciences academic job market

1. Brooklynn Flynn
2. Ariangela J. Kozik
3. You Cheng
4. Ada K. Hagan
5. Jennifer Ng
6. Christopher T. Smith
7. Amanda Haage
8. Nafisa M. Jadavji

Reviewed by preLights

Modeling transcriptional profiles of gene perturbation with deep neural network

1. Wenke Liu
2. Xuya Wang
3. D R Mani
4. David Fenyö

Reviewed by preLights

The RNA binding protein HNRNPA2B1 regulates RNA abundance and motor protein activity in neurites

1. Joelle Lo
2. Katherine F. Vaeth
3. Gurprit Bhardwaj
4. Neelanjan Mukherjee
5. Holger A. Russ
6. Jeffrey K. Moore
7. J. Matthew Taliaferro

Reviewed by preLights

Engineered Nanotopographies Induce Transient Openings in the Nuclear Membrane

1. Einollah Sarikhani
2. Vrund Patel
3. Zhi Li
4. Dhivya Pushpa Meganathan
5. Keivan Rahmani
6. Leah Sadr
7. Ryan Hosseini
8. Diether Visda
9. Shivani Shukla
10. Hamed Naghsh‐Nilchi
11. Adarsh Balaji
12. Gillian McMahon
13. Shaoming Chen
14. Johannes Schöneberg
15. Colleen A. McHugh
16. Lingyan Shi
17. Zeinab Jahed

Reviewed by preLights

Pharyngeal neuronal mechanisms governing sour taste perception in Drosophila melanogaster

1. Bhanu Shrestha
2. Jiun Sang
3. Suman Rimal
4. Youngseok Lee

• Curated by eLife

  eLife Assessment

  This is a useful contribution to our understanding of taste perception. The idea that specific receptors function in the pharynx to mediate responses to carboxylic acids is interesting, although the expression analysis is incomplete. Reviewers also have a number of other suggestions for improvement, including the request that authors provide more details about the methodology used. In general, the claims are supported by solid evidence and add to a growing body of literature on this topic.

Reviewed by eLife, preLights

Feedback regulation by the RhoA-specific GEF ARHGEF17 regulates actomyosin network disassembly

1. Vasundhara Rao
2. Benjamin Grädel
3. Lucien Hinderling
4. Jakobus Van Unen
5. Olivier Pertz

Reviewed by preLights