Evaluated articles

Changes of Small Non-coding RNAs by Severe Acute Respiratory Syndrome Coronavirus 2 Infection

1. Wenzhe Wu
2. Eun-Jin Choi
3. Binbin Wang
4. Ke Zhang
5. Awadalkareem Adam
6. Gengming Huang
7. Leo Tunkle
8. Philip Huang
9. Rohit Goru
10. Isabella Imirowicz
11. Leanne Henry
12. Inhan Lee
13. Jianli Dong
14. Tian Wang
15. Xiaoyong Bao

Reviewed by ScreenIT

Temporal associations of B and T cell immunity with robust vaccine responsiveness in a 16-week interval BNT162b2 regimen

1. Manon Nayrac
2. Mathieu Dubé
3. Gérémy Sannier
4. Alexandre Nicolas
5. Lorie Marchitto
6. Olivier Tastet
7. Alexandra Tauzin
8. Nathalie Brassard
9. Raphaël Lima-Barbosa
10. Guillaume Beaudoin-Bussières
11. Dani Vézina
12. Shang Yu Gong
13. Mehdi Benlarbi
14. Romain Gasser
15. Annemarie Laumaea
16. Jérémie Prévost
17. Catherine Bourassa
18. Gabrielle Gendron-Lepage
19. Halima Medjahed
20. Guillaume Goyette
21. Gloria-Gabrielle Ortega-Delgado
22. Mélanie Laporte
23. Julia Niessl
24. Laurie Gokool
25. Chantal Morrisseau
26. Pascale Arlotto
27. Jonathan Richard
28. Justin Bélair
29. Alexandre Prat
30. Cécile Tremblay
31. Valérie Martel-Laferrière
32. Andrés Finzi
33. Daniel E. Kaufmann

Reviewed by ScreenIT

Reduced sera neutralization to Omicron SARS-CoV-2 by both inactivated and protein subunit vaccines and the convalescents

1. Xin Zhao
2. Dedong Li
3. Wenjing Ruan
4. Rong Zhang
5. Anqi Zheng
6. Shitong Qiao
7. Xinlei Zheng
8. Yingze Zhao
9. Zhihai Chen
10. Lianpan Dai
11. Pengcheng Han
12. George F. Gao

Reviewed by ScreenIT

Possible Cross-Reactivity of Feline and White-Tailed Deer Antibodies against the SARS-CoV-2 Receptor Binding Domain

1. Trevor J. Hancock
2. Peyton Hickman
3. Niloo Kazerooni
4. Melissa Kennedy
5. Stephen A. Kania
6. Michelle Dennis
7. Nicole Szafranski
8. Richard Gerhold
9. Chunlei Su
10. Tom Masi
11. Stephen Smith
12. Tim E. Sparer

Reviewed by ScreenIT

SARS-COV-2 Omicron variant predicted to exhibit higher affinity to ACE-2 receptor and lower affinity to a large range of neutralizing antibodies, using a rapid computational platform

1. Adam Zemla
2. Thomas Desautels
3. Edmond Y. Lau
4. Fangqiang Zhu
5. Kathryn T. Arrildt
6. Brent W. Segelke
7. Shankar Sundaram
8. Daniel Faissol

Reviewed by ScreenIT

A Computational Dissection of Spike protein of SARS-CoV-2 Omicron Variant

1. Zaira Rehman
2. Massab Umair
3. Aamer Ikram
4. Muhammad Salman
5. Syed Adnan Haider
6. Muhammad Ammar

Reviewed by ScreenIT

Modeling and predicting the overlap of B- and T-cell receptor repertoires in healthy and SARS-CoV-2 infected individuals

1. Maria Ruiz Ortega
2. Natanael Spisak
3. Thierry Mora
4. Aleksandra M. Walczak

• Curated by eLife

  Evaluation Summary:

  This work is potentially very important to dissect the immune repertoire of T/B cells, which is one of the most critical/difficult parts for the adaptive immune system to achieve antigen specificity. These conclusions and proposed methods will require additional experimental support and further validation in different disease conditions.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 agreed to share their name with the authors.)

Reviewed by eLife, ScreenIT

Key benefits of dexamethasone and antibody treatment in COVID-19 hamster models revealed by single-cell transcriptomics

1. Emanuel Wyler
2. Julia M. Adler
3. Kathrin Eschke
4. G. Teixeira Alves
5. Stefan Peidli
6. Fabian Pott
7. Julia Kazmierski
8. Laura Michalick
9. Olivia Kershaw
10. Judith Bushe
11. Sandro Andreotti
12. Peter Pennitz
13. Azza Abdelgawad
14. Dylan Postmus
15. Christine Goffinet
16. Jakob Kreye
17. S Momsen Reincke
18. Harald Prüss
19. Nils Blüthgen
20. Achim D. Gruber
21. Wolfgang M. Kuebler
22. Martin Witzenrath
23. Markus Landthaler
24. Geraldine Nouailles
25. Jakob Trimpert

Reviewed by ScreenIT

Pre-clinical evaluation of antiviral activity of nitazoxanide against SARS-CoV-2

1. Jean-Sélim Driouich
2. Maxime Cochin
3. Franck Touret
4. Paul-Rémi Petit
5. Magali Gilles
6. Grégory Moureau
7. Karine Barthélémy
8. Caroline Laprie
9. Thanaporn Wattanakul
10. Palang Chotsiri
11. Richard M. Hoglund
12. Joel Tarning
13. Laurent Fraisse
14. Peter Sjö
15. Charles E. Mowbray
16. Fanny Escudié
17. Ivan Scandale
18. Eric Chatelain
19. Xavier de Lamballerie
20. Caroline Solas
21. Antoine Nougairède

Reviewed by ScreenIT

Modeling the dynamics of within-host viral infection and evolution predicts quasispecies distributions and phase boundaries separating distinct classes of infections

1. Greyson R. Lewis
2. Wallace F. Marshall
3. Barbara A. Jones

Reviewed by ScreenIT

Structure prediction of the druggable fragments in SARS-CoV-2 untranslated regions

1. Julita Gumna
2. Maciej Antczak
3. Ryszard W. Adamiak
4. Janusz M. Bujnicki
5. Shi-Jie Chen
6. Feng Ding
7. Pritha Ghosh
8. Jun Li
9. Sunandan Mukherjee
10. Chandran Nithin
11. Katarzyna Pachulska-Wieczorek
12. Almudena Ponce-Salvatierra
13. Mariusz Popenda
14. Joanna Sarzynska
15. Tomasz Wirecki
16. Dong Zhang
17. Sicheng Zhang
18. Tomasz Zok
19. Eric Westhof
20. Marta Szachniuk
21. Zhichao Miao
22. Agnieszka Rybarczyk

Reviewed by ScreenIT

In vitro and computational analysis of the putative furin cleavage site (RRARS) in the divergent spike protein of the rodent coronavirus AcCoV-JC34 (sub-genus luchacovirus)

1. Annette Choi
2. Deanndria T. Singleton
3. Alison E. Stout
4. Jean K. Millet
5. Gary R. Whittaker

Reviewed by ScreenIT

Human Genetic Variants Associated with COVID-19 Severity are Enriched in Immune and Epithelium Regulatory Networks

1. Zhanying Feng
2. Xianwen Ren
3. Zhana Duren
4. Yong Wang

Reviewed by ScreenIT

The rise and fall of SARS-CoV-2 variants and the mutational profile of Omicron

1. Tanner Wiegand
2. Aidan McVey
3. Anna Nemudraia
4. Artem Nemudryi
5. Blake Wiedenheft

Reviewed by ScreenIT

Disrupted Peyer’s Patch Microanatomy in COVID-19 Including Germinal Centre Atrophy Independent of Local Virus

1. Silvia C. Trevelin
2. Suzanne Pickering
3. Katrina Todd
4. Cynthia Bishop
5. Michael Pitcher
6. Jose Garrido Mesa
7. Lucia Montorsi
8. Filomena Spada
9. Nedyalko Petrov
10. Anna Green
11. Manu Shankar-Hari
12. Stuart J.D. Neil
13. Jo Spencer

Reviewed by ScreenIT

Variable loss of antibody potency against SARS-CoV-2 B.1.1.529 (Omicron)

1. Daniel J. Sheward
2. Changil Kim
3. Roy A. Ehling
4. Alec Pankow
5. Xaquin Castro Dopico
6. Darren Martin
7. Sai Reddy
8. Joakim Dillner
9. Gunilla B. Karlsson Hedestam
10. Jan Albert
11. Ben Murrell

Reviewed by ScreenIT

SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization

1. Dhiraj Mannar
2. James W. Saville
3. Zehua Sun
4. Xing Zhu
5. Michelle M. Marti
6. Shanti S. Srivastava
7. Alison M. Berezuk
8. Steven Zhou
9. Katharine S. Tuttle
10. Michele D. Sobolewski
11. Andrew Kim
12. Benjamin R. Treat
13. Priscila Mayrelle Da Silva Castanha
14. Jana L. Jacobs
15. Simon M. Barratt-Boyes
16. John W. Mellors
17. Dimiter S. Dimitrov
18. Wei Li
19. Sriram Subramaniam

Reviewed by ScreenIT

ACE2-containing defensosomes serve as decoys to inhibit SARS-CoV-2 infection

1. Krystal L. Ching
2. Maren de Vries
3. Juan Gago
4. Kristen Dancel-Manning
5. Joseph Sall
6. William J. Rice
7. Clea Barnett
8. Alireza Khodadadi-Jamayran
9. Aristotelis Tsirigos
10. Feng-Xia Liang
11. Lorna E. Thorpe
12. Bo Shopsin
13. Leopoldo N. Segal
14. Meike Dittmann
15. Victor J. Torres
16. Ken Cadwell

Reviewed by ScreenIT

Neutrophil profiles of pediatric COVID-19 and multisystem inflammatory syndrome in children

1. Brittany P. Boribong
2. Thomas J. LaSalle
3. Yannic C. Bartsch
4. Felix Ellett
5. Maggie E. Loiselle
6. Jameson P. Davis
7. Anna L.K. Gonye
8. David B. Sykes
9. Soroush Hajizadeh
10. Johannes Kreuzer
11. Shiv Pillai
12. Wilhelm Haas
13. Andrea G. Edlow
14. Alessio Fasano
15. Galit Alter
16. Daniel Irimia
17. Moshe Sade-Feldman
18. Lael M. Yonker

Reviewed by ScreenIT

How effective is vaccination protection?

1. Milan Batista
2. Aleksej Turnšek

Reviewed by ScreenIT