Latest preprint reviews

  1. Dynamic organization of visual cortical networks inferred from massive spiking datasets

    This article has 3 authors:
    1. Colin Graber
    2. Yurii Vlasov
    3. Alexander Schwing
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      The authors describe a model for tracking time-varying functional connectivity between neurons from multi-electrode spike recordings. This is an interesting and potentially useful approach to an open problem in neural data analysis, and could be an essential tool for investigating the neural code from large-scale in-vivo recordings of spiking activity. However, the evidence is incomplete: systematic comparisons with existing methods and/or demonstration of its utility relative to conventional methods are essential to demonstrate the usefulness of the method.

    Reviewed by eLife

    This article has 7 evaluationsAppears in 1 listLatest version Latest activity
  2. Staphylococcus aureus counters organic acid anion-mediated inhibition of peptidoglycan cross-linking through robust alanine racemase activity

    This article has 11 authors:
    1. Sasmita Panda
    2. Yahani P Jayasinghe
    3. Dhananjay D Shinde
    4. Emilio Bueno
    5. Amanda Stastny
    6. Blake P Bertrand
    7. Sujata S Chaudhari
    8. Tammy Kielian
    9. Felipe Cava
    10. Donald R Ronning
    11. Vinai C Thomas
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      In this useful study, the authors present convincing evidence linking the enzyme D-alanine-D-alanine ligase (Ddl), crucial for cell wall fortification, to organic acid exposure in Staphylococcus aureus. While it's established that organic acids impede bacterial growth, the researchers reveal a novel coping mechanism where S. aureus maintains elevated levels of D-alanine, the substrate for Ddl, to counteract this inhibition. This discovery illuminates a bacterial strategy for organic acid tolerance, offering new insights for microbiologists and potentially informing future antimicrobial approaches.

    Reviewed by eLife, Arcadia Science

    This article has 8 evaluationsAppears in 3 listsLatest version Latest activity
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