Microbiology

Protection of human ACE2 transgenic Syrian hamsters from SARS CoV-2 variants by human polyclonal IgG from hyper-immunized transchromosomic bovines

1. Theron Gilliland
2. Yanan Liu
3. Rong Li
4. Matthew Dunn
5. Emily Cottle
6. Yutaka Terada
7. Zachary Ryckman
8. Maria Alcorn
9. Shauna Vasilatos
10. Jeneveve Lundy
11. Deanna Larson
12. Hua Wu
13. Thomas Luke
14. Christoph Bausch
15. Kristi Egland
16. Eddie Sullivan
17. Zhongde Wang
18. William B. Klimstra

Reviewed by ScreenIT

A qnr-plasmid allows aminoglycosides to induce SOS in Escherichia coli

1. Anamaria Babosan
2. David Skurnik
3. Anaëlle Muggeo
4. Gerald B Pier
5. Zeynep Baharoglu
6. Thomas Jové
7. Marie-Cécile Ploy
8. Sophie Griveau
9. Fethi Bedioui
10. Sébastien Vergnolle
11. Sophie Moussalih
12. Christophe de Champs
13. Didier Mazel
14. Thomas Guillard

• Curated by eLife

  Evaluation Summary:

  This manuscript describes how a small plasmid containing a quinolone resistance determinant changes the cellular response to sub-inhibitory concentrations of Tobramycin. Authors have found that Escherichia coli cells carrying this plasmid undergo nitrosative stress mediated by two previously uncharacterized genes, which leads to induction of the SOS response, a well described stress response in bacteria. These findings are relevant for readers across the microbiology and genetics fields.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 agreed to share their name with the authors.)

Reviewed by eLife

ADAR mediated A-to-I RNA editing affects SARS-CoV-2 characteristics and fuels its evolution

1. Yulong Song
2. Xiuju He
3. Wenbing Yang
4. Tian Tang
5. Rui Zhang

Reviewed by ScreenIT

Unlike Chloroquine, Mefloquine Inhibits SARS-CoV-2 Infection in Physiologically Relevant Cells

1. Carolina Q. Sacramento
2. Natalia Fintelman-Rodrigues
3. Suelen S. G. Dias
4. Jairo R. Temerozo
5. Aline de Paula D. Da Silva
6. Carine S. da Silva
7. Camilla Blanco
8. André C. Ferreira
9. Mayara Mattos
10. Vinicius C. Soares
11. Filipe Pereira-Dutra
12. Milene Dias Miranda
13. Debora F. Barreto-Vieira
14. Marcos Alexandre N. da Silva
15. Suzana S. Santos
16. Mateo Torres
17. Otávio Augusto Chaves
18. Rajith K. R. Rajoli
19. Alberto Paccanaro
20. Andrew Owen
21. Dumith Chequer Bou-Habib
22. Patrícia T. Bozza
23. Thiago Moreno L. Souza

Reviewed by ScreenIT

Comparison of heat-inactivated and infectious SARS-CoV-2 across indoor surface materials shows comparable RT-qPCR viral signal intensity and persistence

1. Rodolfo A. Salido
2. Victor J. Cantú
3. Alex E. Clark
4. Sandra L. Leibel
5. Anahid Foroughishafiei
6. Anushka Saha
7. Abbas Hakim
8. Alhakam Nouri
9. Alma L. Lastrella
10. Anelizze Castro-Martínez
11. Ashley Plascencia
12. Bhavika Kapadia
13. Bing Xia
14. Christopher Ruiz
15. Clarisse A. Marotz
16. Daniel Maunder
17. Elijah S. Lawrence
18. Elizabeth W. Smoot
19. Emily Eisner
20. Evelyn S. Crescini
21. Laura Kohn
22. Lizbeth Franco Vargas
23. Marisol Chacón
24. Maryann Betty
25. Michal Machnicki
26. Min Yi Wu
27. Nathan A. Baer
28. Pedro Belda-Ferre
29. Peter De Hoff
30. Phoebe Seaver
31. R. Tyler Ostrander
32. Rebecca Tsai
33. Shashank Sathe
34. Stefan Aigner
35. Sydney C. Morgan
36. Toan T. Ngo
37. Tom Barber
38. Willi Cheung
39. Aaron F. Carlin
40. Gene W. Yeo
41. Louise C. Laurent
42. Rebecca Fielding-Miller
43. Rob Knight

Reviewed by ScreenIT

The SARS-CoV-2 Reproduction Number R0 in Cats

1. Jose L. Gonzales
2. Mart C. M. de Jong
3. Nora M. Gerhards
4. Wim H. M. Van der Poel

Reviewed by ScreenIT

The in vitro and in vivo potency of CT-P59 against Delta and its associated variants of SARS-CoV-2

1. Dong-Kyun Ryu
2. Hye-Min Woo
3. Bobin Kang
4. Hanmi Noh
5. Jong-In Kim
6. Ji-Min Seo
7. Cheolmin Kim
8. Minsoo Kim
9. Jun-Won Kim
10. Nayoung Kim
11. Pyeonghwa Jeon
12. Hansaem Lee
13. Jeong-Sun Yang
14. Kyung-Chang Kim
15. Joo-Yeon Lee
16. Min-Ho Lee
17. Sang-Seok Oh
18. Hyo-Young Chung
19. Ki-Sung Kwon
20. Soo-Young Lee

Reviewed by ScreenIT

The Plasmodium NOT1-G paralogue is an essential regulator of sexual stage maturation and parasite transmission

1. Kevin J. Hart
2. B. Joanne Power
3. Kelly T. Rios
4. Aswathy Sebastian
5. Scott E. Lindner

Reviewed by Review Commons

CRISPR screens for host factors critical for infection by SARS-CoV-2 variants of concern identify GATA6 as a central modulator of ACE2

1. Ma’ayan Israeli
2. Yaara Finkel
3. Yfat Yahalom-Ronen
4. Nir Paran
5. Theodor Chitlaru
6. Ofir Israeli
7. Inbar Cohen-Gihon
8. Moshe Aftalion
9. Reut Falach
10. Uri Elia
11. Ital Nemet
12. Limor Kliker
13. Michal Mandelboim
14. Adi Beth-Din
15. Tomer Israely
16. Ofer Cohen
17. Noam Stern-Ginossar
18. Adi Bercovich-Kinori

Reviewed by ScreenIT

Key Substitutions in the Spike Protein of SARS-CoV-2 Variants Can Predict Resistance to Monoclonal Antibodies, but Other Substitutions Can Modify the Effects

1. Sabrina Lusvarghi
2. Wei Wang
3. Rachel Herrup
4. Sabari Nath Neerukonda
5. Russell Vassell
6. Lisa Bentley
7. Ann E. Eakin
8. Karl J. Erlandson
9. Carol D. Weiss

Reviewed by ScreenIT