Microbiology

High efficacy of therapeutic equine hyperimmune antibodies against SARS-CoV-2 variants of concern

1. Andres Moreira-Soto
2. Mauricio Arguedas
3. Hebleen Brenes
4. Willem Buján
5. Eugenia Corrales-Aguilar
6. Cecilia Díaz
7. Ann Echeverri
8. Marietta Flores-Díaz
9. Aarón Gómez
10. Andrés Hernández
11. María Herrera
12. Guillermo León
13. Román Macaya
14. Arne Kühne
15. José Arturo Molina-Mora
16. Javier Mora
17. Alfredo Sanabria
18. Andrés Sánchez
19. Laura Sánchez
20. Álvaro Segura
21. Eduardo Segura
22. Daniela Solano
23. Claudio Soto
24. Jennifer L. Stynoski
25. Mariángela Vargas
26. Mauren Villalta
27. Chantal B E M Reusken
28. Christian Drosten
29. José María Gutiérrez
30. Alberto Alape-Girón
31. Jan Felix Drexler

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Exposure route, sex, and age influence disease outcome in a golden Syrian hamster model of SARS-CoV-2 infection

1. Bryan D. Griffin
2. Bryce M. Warner
3. Mable Chan
4. Emelissa J. Mendoza
5. Nikesh Tailor
6. Logan Banadyga
7. Anders Leung
8. Shihua He
9. Amrit S. Boese
10. Jonathan Audet
11. Wenguang Cao
12. Estella Moffat
13. Lauren Garnett
14. Kevin Tierney
15. Kaylie N. Tran
16. Alixandra Albietz
17. Kathy Manguiat
18. Geoff Soule
19. Alexander Bello
20. Robert Vendramelli
21. Jessica Lin
22. Yvon Deschambault
23. Wenjun Zhu
24. David Safronetz
25. Heidi Wood
26. Samira Mubareka
27. James E. Strong
28. Carissa Embury-Hyatt
29. Darwyn Kobasa

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Linking plasmid-based beta-lactamases to their bacterial hosts using single-cell fusion PCR

1. Peter J Diebold
2. Felicia N New
3. Michael Hovan
4. Michael J Satlin
5. Ilana L Brito

• Curated by eLife

  Evaluation Summary:

  Tracking horizontal gene transfer of mobile resistance genes is exceptionally important in the context of AMR and its burden on public health. An accessible high-throughput technique that provides an alternative to Hi-C or single-cell whole genome sequencing for associating mobile antibiotic resistance genes with their bacterial hosts in complex microbial populations is an important development for the field. The method introduced here, which relies on cellular emulsion and fusion PCR in one step, is an improvement over the previously published epicPCR. In addition, the method can be applied to other studies on complex microbial communities beyond antibiotic resistance.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 agreed to share their name with the authors.)

Reviewed by eLife

UK B.1.1.7 variant exhibits increased respiratory replication and shedding in nonhuman primates

1. K. Rosenke
2. F. Feldmann
3. A. Okumura
4. F. Hansen
5. T. Tang-Huau
6. K. Meade-White
7. B. Kaza
8. B.J. Smith
9. P. W. Hanley
10. J. Lovaglio
11. M. A. Jarvis
12. C. Shaia
13. H. Feldmann

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A nascent polypeptide sequence modulates DnaA translation elongation in response to nutrient availability

1. Michele Felletti
2. Cédric Romilly
3. E Gerhart H Wagner
4. Kristina Jonas

Reviewed by Review Commons

A Combination of Receptor-Binding Domain and N-Terminal Domain Neutralizing Antibodies Limits the Generation of SARS-CoV-2 Spike Neutralization-Escape Mutants

1. Denise Haslwanter
2. M. Eugenia Dieterle
3. Anna Z. Wec
4. Cecilia M. O’Brien
5. Mrunal Sakharkar
6. Catalina Florez
7. Karen Tong
8. C. Garrett Rappazzo
9. Gorka Lasso
10. Olivia Vergnolle
11. Ariel S. Wirchnianski
12. Robert H. Bortz
13. Ethan Laudermilch
14. J. Maximilian Fels
15. Amanda Mengotto
16. Ryan J. Malonis
17. George I. Georgiev
18. Jose A. Quiroz
19. Daniel Wrapp
20. Nianshuang Wang
21. Kathryn E. Dye
22. Jason Barnhill
23. John M. Dye
24. Jason S. McLellan
25. Johanna P. Daily
26. Jonathan R. Lai
27. Andrew S. Herbert
28. Laura M. Walker
29. Kartik Chandran
30. Rohit K. Jangra

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The lag in SARS-CoV-2 genome submissions to GISAID

1. Kishan Kalia
2. Gayatri Saberwal
3. Gaurav Sharma

Reviewed by ScreenIT

An outbreak of SARS-CoV-2 with high mortality in mink (Neovison vison) on multiple Utah farms

1. Chrissy D. Eckstrand
2. Thomas J. Baldwin
3. Kerry A. Rood
4. Michael J. Clayton
5. Jason K. Lott
6. Rebecca M. Wolking
7. Daniel S. Bradway
8. Timothy Baszler

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Second-Generation Antibodies Neutralize Emerging SARS-CoV-2 Variants of Concern

1. Branislav Kovacech
2. Lubica Fialova
3. Peter Filipcik
4. Rostislav Skrabana
5. Monika Zilkova
6. Natalia Paulenka-Ivanovova
7. Andrej Kovac
8. Denisa Palova
9. Gabriela Paulíkova Rolkova
10. Katarina Tomkova
11. Natalia Turic Csokova
12. Karina Markova
13. Michaela Skrabanova
14. Kristina Sinska
15. Neha Basheer
16. Petra Majerova
17. Jozef Hanes
18. Vojtech Parrak
19. Michal Prcina
20. Ondrej Cehlar
21. Martin Cente
22. Juraj Piestansky
23. Michal Fresser
24. Michal Novak
25. Monika Slavikova
26. Kristina Borsova
27. Viktoria Cabanova
28. Bronislava Brejova
29. Tomas Vinař
30. Jozef Nosek
31. Boris Klempa
32. Norbert Zilka
33. Eva Kontsekova

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Intranasal Administration of a Monoclonal Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection

1. Sandro Halwe
2. Alexandra Kupke
3. Kanika Vanshylla
4. Falk Liberta
5. Henning Gruell
6. Matthias Zehner
7. Cornelius Rohde
8. Verena Krähling
9. Michelle Gellhorn Serra
10. Christoph Kreer
11. Michael Klüver
12. Lucie Sauerhering
13. Jörg Schmidt
14. Zheng Cai
15. Fei Han
16. David Young
17. Guangwei Yang
18. Marek Widera
19. Manuel Koch
20. Anke Werner
21. Lennart Kämper
22. Nico Becker
23. Michael S. Marlow
24. Markus Eickmann
25. Sandra Ciesek
26. Felix Schiele
27. Florian Klein
28. Stephan Becker

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