Microbiology

Phylogenetic analysis of human parainfluenza type 3 virus strains responsible for the outbreak during the COVID-19 pandemic in Seoul, South Korea

1. Ha Nui Kim
2. Soo-Young Yoon
3. Chae Seung Lim
4. Chang Kyu Lee
5. Jung Yoon

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Pulmonary lesions following inoculation with the SARS-CoV-2 Omicron BA.1 (B.1.1.529) variant in Syrian golden hamsters

1. Melanie Rissmann
2. Danny Noack
3. Debby van Riel
4. Katharina S. Schmitz
5. Rory D. de Vries
6. Peter van Run
7. Mart M. Lamers
8. Corine H. Geurts van Kessel
9. Marion P. G. Koopmans
10. Ron A. M. Fouchier
11. Thijs Kuiken
12. Bart L. Haagmans
13. Barry Rockx

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Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model

1. Peter A. C. Wing
2. Maria Prange-Barczynska
3. Amy Cross
4. Stefania Crotta
5. Claudia Orbegozo Rubio
6. Xiaotong Cheng
7. James M. Harris
8. Xiaodong Zhuang
9. Rachel L. Johnson
10. Kathryn A. Ryan
11. Yper Hall
12. Miles W. Carroll
13. Fadi Issa
14. Peter Balfe
15. Andreas Wack
16. Tammie Bishop
17. Francisco J. Salguero
18. Jane A. McKeating

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Vascular dysregulation following SARS-CoV-2 infection involves integrin signalling through a VE-Cadherin mediated pathway

1. Danielle Nader
2. Steve Kerrigan

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The SARS-CoV-2 Delta variant induces an antibody response largely focused on class 1 and 2 antibody epitopes

1. Allison J. Greaney
2. Rachel T. Eguia
3. Tyler N. Starr
4. Khadija Khan
5. Nicholas Franko
6. Jennifer K. Logue
7. Sandra M. Lord
8. Cate Speake
9. Helen Y. Chu
10. Alex Sigal
11. Jesse D. Bloom

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Immunization with recombinant accessory protein-deficient SARS-CoV-2 protects against lethal challenge and viral transmission

1. Chengjin Ye
2. Jun-Gyu Park
3. Kevin Chiem
4. Piyush Dravid
5. Anna Allué-Guardia
6. Andreu Garcia-Vilanova
7. Amit Kapoor
8. Mark R. Walter
9. James J. Kobie
10. Richard K. Plemper
11. Jordi B. Torrelles
12. Luis Martinez-Sobrido

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A broad and potent neutralization epitope in SARS-related coronaviruses

1. Meng Yuan
2. Xueyong Zhu
3. Wan-ting He
4. Panpan Zhou
5. Chengzi I. Kaku
6. Tazio Capozzola
7. Connie Y. Zhu
8. Xinye Yu
9. Hejun Liu
10. Wenli Yu
11. Yuanzi Hua
12. Henry Tien
13. Linghang Peng
14. Ge Song
15. Christopher A. Cottrell
16. William R. Schief
17. David Nemazee
18. Laura M. Walker
19. Raiees Andrabi
20. Dennis R. Burton
21. Ian A. Wilson

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Tracking SARS-CoV-2 Omicron diverse spike gene mutations identifies multiple inter-variant recombination events

1. Junxian Ou
2. Wendong Lan
3. Xiaowei Wu
4. Tie Zhao
5. Biyan Duan
6. Peipei Yang
7. Yi Ren
8. Lulu Quan
9. Wei Zhao
10. Donald Seto
11. James Chodosh
12. Zhen Luo
13. Jianguo Wu
14. Qiwei Zhang

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Development of a ferritin-based nanoparticle vaccine against the SARS-CoV-2 Omicron variant

1. Wanbo Tai
2. Benjie Chai
3. Shengyong Feng
4. Xinyu Zhuang
5. Jun Ma
6. Mujia Pang
7. Lin Pan
8. Zi Yang
9. Mingyao Tian
10. Gong Cheng

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Reconstitution of surface lipoprotein translocation through the Slam translocon

1. Minh Sang Huynh
2. Yogesh Hooda
3. Yuzi Raina Li
4. Maciej Jagielnicki
5. Christine Chieh-Lin Lai
6. Trevor F Moraes

• Curated by eLife

  Evaluation Summary:

  This work provides new insights into how surface-exposed lipoproteins of Gram-negative bacteria reach their destination in the outer membrane. Authors find that the outer membrane protein complex Slam serves as a translocon for the lipoproteins and the periplasmic chaperone Skp mediates their targeting to Slam. This work may contribute to the elucidation of host invasion mechanisms by pathogenic bacteria, in which surface lipoproteins play an important role.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

Reviewed by eLife