Microbiology

  1. Near-native state imaging by cryo-soft-X-ray tomography reveals remodelling of multiple cellular organelles during HSV-1 infection

    1. Kamal L. Nahas
    2. Viv Connor
    3. Katharina M. Scherer
    4. Clemens F. Kaminski
    5. Maria Harkiolaki
    6. Colin M. Crump
    7. Stephen C. Graham

    Reviewed by Review Commons

    4 evaluationsAppears in 2 listsLatest version Latest activity

  2. The SARS-CoV-2 Cellular Receptor ACE2 is expressed in Oropharyngeal Cells and is modulated in vitro by the Bacterial Lysate Lantigen B

    1. Caterina Pizzimenti
    2. Antonella D’Agostino
    3. Paola Pirrello
    4. Alessia Ruiba
    5. Giovanni Melioli

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  3. Cell cycle independent role of cyclin D3 in host restriction of SARS-CoV-2 infection

    1. Ravi K. Gupta
    2. Petra Mlcochova

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. ORF6 protein of SARS-CoV-2 inhibits TRIM25 mediated RIG-I ubiquitination to mitigate type I IFN induction

    1. Oyahida Khatun
    2. Mansi Sharma
    3. Rohan Narayan
    4. Shashank Tripathi

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  5. SARS-CoV-2 Evolution and Patient Immunological History Shape the Breadth and Potency of Antibody-Mediated Immunity

    1. Maria Manali
    2. Laura A Bissett
    3. Julien A R Amat
    4. Nicola Logan
    5. Sam Scott
    6. Ellen C Hughes
    7. William T Harvey
    8. Richard Orton
    9. Emma C Thomson
    10. Rory N Gunson
    11. Mafalda Viana
    12. Brian Willett
    13. Pablo R Murcia

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. Reaction Conditions Promoting the Specific Detection of SARS-CoV-2 NendoU Enzymatic Activity

    1. Nodar Makharashvili
    2. James O. McNamara

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  7. SARS-CoV-2 Omicron subvariants evolved to promote further escape from MHC-I recognition

    1. Miyu Moriyama
    2. Carolina Lucas
    3. Valter Silva Monteiro
    4. Yale SARS-CoV-2 Genomic Surveillance Initiative
    5. Akiko Iwasaki

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. Neutralisation sensitivity of SARS-CoV-2 omicron subvariants to therapeutic monoclonal antibodies

    1. Daichi Yamasoba
    2. Yusuke Kosugi
    3. Izumi Kimura
    4. Shigeru Fujita
    5. Keiya Uriu
    6. Jumpei Ito
    7. Kei Sato

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  9. Soluble MAC is primarily released from MAC-resistant bacteria that potently convert complement component C5

    1. Dennis J Doorduijn
    2. Marie V Lukassen
    3. Marije FL van 't Wout
    4. Vojtech Franc
    5. Maartje Ruyken
    6. Bart W Bardoel
    7. Albert JR Heck
    8. Suzan HM Rooijakkers

    • Curated by eLife

      Evaluation Summary:

      The soluble membrane attack complex (sMAC) is generated from complement activation and contains the complement proteins C5b, C6, C7, C8, C9 together with the regulatory proteins clusterin and vitronectin. Despite intense interest in sMAC, the mechanisms regulating its formation remain poorly understood. In this manuscript the authors demonstrate that sMAC is formed when complement is activated on bacteria that are resistant to killing by MAC pores.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 agreed to share their name with the authors.)

    Reviewed by eLife

    3 evaluationsAppears in 1 listLatest version Latest activity

  10. Gas6 drives Zika virus-induced neurological complications in humans and congenital syndrome in immunocompetent mice

    1. Joao Luiz Silva-Filho
    2. Lilian G. de Oliveira
    3. Leticia Monteiro
    4. Pierina L. Parise
    5. Nagela G. Zanluqui
    6. Carolina M. Polonio
    7. Carla L. de Freitas
    8. Daniel A. Toledo-Teixeira
    9. William M. de Souza
    10. Najara Bittencourt
    11. Mariene R. Amorim
    12. Julia Forato
    13. Stéfanie P. Muraro
    14. Gabriela F. de Souza
    15. Matheus C. Martini
    16. Karina Bispo-dos-Santos
    17. Aline Vieira
    18. Carla C. Judice
    19. Glaucia M. Pastore
    20. Eliana Amaral
    21. Renato Passini Junior
    22. Helaine M.B.P. Mayer-Milanez
    23. Carolina C. Ribeiro-do-Valle
    24. Roseli Calil
    25. João Renato Bennini Junior
    26. Giuliane J. Lajos
    27. Albina Altemani
    28. Marcos T. Nolasco da Silva
    29. Ana Carolina Coan
    30. Maria Francisca Colella-Santos
    31. Andrea P.B. von Zuben
    32. Marco Aurélio R. Vinolo
    33. Clarice Weis Arns
    34. Rodrigo Ramos Catharino
    35. Maria Laura Costa
    36. Rodrigo N. Angerami
    37. André R.R. Freitas
    38. Mariangela R. Resende
    39. Márcia T. Garcia
    40. Maria Luiza Moretti
    41. Laurent Renia
    42. Lisa F.P. Ng
    43. Carla V. Rothlin
    44. Fabio T.M. Costa
    45. Jean Pierre Schatzmann Peron
    46. José Luiz Proença-Modena

    • Curated by eLife

      Evaluation Summary:

      The pathophysiology of Zika virus infection remains an area of high research interest. In this study, the authors use diverse experimental models to examine the potential role of Gas6 in Zika virus infection and associated neurological sequelae.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity
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