Immunology

SARS‐CoV‐2 infection activates dendritic cells via cytosolic receptors rather than extracellular TLRs

1. Lieve E.H. van der Donk
2. Julia Eder
3. John L. van Hamme
4. Philip J. M. Brouwer
5. Mitch Brinkkemper
6. Ad C. van Nuenen
7. Marit J. van Gils
8. Rogier W. Sanders
9. Neeltje A. Kootstra
10. Marta Bermejo‐Jambrina
11. Teunis B. H. Geijtenbeek

Reviewed by ScreenIT

Absence of severe COVID-19 in patients with clonal mast cells activation disorders: effective anti-SARS-CoV-2 immune response

1. Julien Rossignol
2. Amani Ouedrani
3. Cristina Bulai Livideanu
4. Stéphane Barete
5. Louis Terriou
6. David Launay
7. Richard Lemal
8. Celine Greco
9. Laurent Frenzel
10. Cecile Meni
11. Christine Bodemere-Skandalis
12. Laura Polivka
13. Anne-Florence Collange
14. Hassiba Hachichi
15. Sonia Bouzourine
16. Djazira Nait Messaoud
17. Mathilde Negretto
18. Laurence Vendrame
19. Marguerite Jambou
20. Marie Gousseff
21. Stéphane Durupt
22. Jean-Christophe Lega
23. Jean-Marc Durand
24. Caroline Gaudy
25. Gandhi Damaj
26. Marie-Pierre Gourin
27. Mohamed Hamidou
28. Laurence Bouillet
29. Edwige Le Mouel
30. Alexandre Maria
31. Patricia Zunic
32. Quentin Cabrera
33. Denis Vincent
34. Christian Lavigne
35. Etienne Riviere
36. Clement Gourguechon
37. Anne Brignier
38. Ludovic Lhermitte
39. Thierry Jo Molina
40. Julie Bruneau
41. Julie Agopian
42. Patrice Dubreuil
43. Dana Ranta
44. Alexandre Mania
45. Michel Arock
46. Isabelle Staropoli
47. Olivier Tournilhac
48. Olivier Lortholary
49. Olivier Schwartz
50. Lucienne Chatenoud
51. Olivier Hermine

Reviewed by ScreenIT

Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity reduces lung inflammation

1. Koen K.A. Van Rompay
2. Katherine J. Olstad
3. Rebecca L. Sammak
4. Joseph Dutra
5. Jennifer K. Watanabe
6. Jodie L. Usachenko
7. Ramya Immareddy
8. Jamin W. Roh
9. Anil Verma
10. Yashavanth Shaan Lakshmanappa
11. Brian A. Schmidt
12. Clara Di Germanio
13. Nabeela Rizvi
14. Mars Stone
15. Graham Simmons
16. Larry J. Dumont
17. A. Mark Allen
18. Sarah Lockwood
19. Rachel E. Pollard
20. Rafael Ramiro de Assis
21. JoAnn L. Yee
22. Peter B. Nham
23. Amir Ardeshir
24. Jesse D. Deere
25. Jean Patterson
26. Aarti Jain
27. Philip L. Felgner
28. Smita S. Iyer
29. Dennis J. Hartigan-O’Connor
30. Michael P. Busch
31. J. Rachel Reader

Reviewed by ScreenIT

Subtle immunological differences in mRNA-1273 and BNT162b2 COVID-19 vaccine induced Fc-functional profiles

1. Paulina Kaplonek
2. Deniz Cizmeci
3. Stephanie Fischinger
4. Ai-ris Collier
5. Todd Suscovich
6. Caitlyn Linde
7. Thomas Broge
8. Colin Mann
9. Fatima Amanat
10. Diana Dayal
11. Justin Rhee
12. Michael de St. Aubin
13. Eric J. Nilles
14. Elon R. Musk
15. Anil S. Menon
16. Erica Ollmann Saphire
17. Florian Krammer
18. Douglas A. Lauffenburger
19. Dan H. Barouch
20. Galit Alter

Reviewed by Rapid Reviews Infectious Diseases, ScreenIT

Microglia and CD206+ border-associated mouse macrophages maintain their embryonic origin during Alzheimer’s disease

1. Xiaoting Wu
2. Takashi Saito
3. Takaomi C Saido
4. Anna M Barron
5. Christiane Ruedl

• Curated by eLife

  Evaluation Summary:

  This study by Wu et al., examined in a mouse model of Alzheimer how the lifespan and kinetics of both border-associated myeloid cells and microglia are affected. Taken together, these data provide evidence on the replenishment of CNS-associated myeloid cells under both steady-state and pathology.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

Reviewed by eLife

Intravenous administration of BCG protects mice against lethal SARS-CoV-2 challenge

1. Kerry L. Hilligan
2. Sivaranjani Namasivayam
3. Chad S. Clancy
4. Danielle O’Mard
5. Sandra D. Oland
6. Shelly J. Robertson
7. Paul J. Baker
8. Ehydel Castro
9. Nicole L. Garza
10. Bernard A.P. Lafont
11. Reed Johnson
12. Franca Ronchese
13. Katrin D. Mayer-Barber
14. Sonja M. Best
15. Alan Sher

Reviewed by ScreenIT

The pigtail macaque (Macaca nemestrina) model of COVID-19 reproduces diverse clinical outcomes and reveals new and complex signatures of disease

1. Alexandra Melton
2. Lara A. Doyle-Meyers
3. Robert V. Blair
4. Cecily Midkiff
5. Hunter J. Melton
6. Kasi Russell-Lodrigue
7. Pyone P. Aye
8. Faith Schiro
9. Marissa Fahlberg
10. Dawn Szeltner
11. Skye Spencer
12. Brandon J. Beddingfield
13. Kelly Goff
14. Nadia Golden
15. Toni Penney
16. Breanna Picou
17. Krystle Hensley
18. Kristin E. Chandler
19. Jessica A. Plante
20. Kenneth S. Plante
21. Scott C. Weaver
22. Chad J. Roy
23. James A. Hoxie
24. Hongmei Gao
25. David C. Montefiori
26. Joseph L. Mankowski
27. Rudolf P. Bohm
28. Jay Rappaport
29. Nicholas J. Maness

Reviewed by ScreenIT

Directing an mRNA-LNP vaccine toward lymph nodes improves humoral and cellular immunity against SARS-CoV-2

1. David M. Francis
2. Runqiang Chen
3. Sahba Khorsandzadeh
4. Qidong Hu
5. Xiaoxuan Lyu
6. Hua Wang
7. Wan-lin Lim
8. Haotian Sun
9. Hui Xie
10. Namir Shaabani
11. Russell Ross
12. Brian Cooley
13. Henry Ji

Reviewed by ScreenIT

An Intranasal OMV-Based Vaccine Induces High Mucosal and Systemic Protecting Immunity Against a SARS-CoV-2 Infection

1. Peter A. van der Ley
2. Afshin Zariri
3. Elly van Riet
4. Dinja Oosterhoff
5. Corine P. Kruiswijk

Reviewed by ScreenIT

The Lambda variant of SARS-CoV-2 has a better chance than the Delta variant to escape vaccines

1. Haolin Liu
2. Pengcheng Wei
3. Qianqian Zhang
4. Katja Aviszus
5. Jared Linderberger
6. John Yang
7. Junfeng Liu
8. Zhongzhou Chen
9. Hassan Waheed
10. Lyndon Reynoso
11. Gregory P. Downey
12. Stephen K. Frankel
13. John Kappler
14. Philippa Marrack
15. Gongyi Zhang

Reviewed by ScreenIT