Immunology

  1. Neutralizing antibody-independent immunity to SARS-CoV-2 in hamsters and hACE-2 transgenic mice immunized with a RBD/Nucleocapsid fusion protein

    1. Julia T. Castro
    2. Marcílio J. Fumagalli
    3. Natalia S. Hojo-Souza
    4. Patrick Azevedo
    5. Natalia Salazar
    6. Bruna Rattis
    7. Simone G. Ramos
    8. Lídia Faustino
    9. Gregório G. Almeida
    10. Livia I. Oliveira
    11. Tomas G. Marçal
    12. Marconi Augusto
    13. Rubens Magalhães
    14. Bruno Cassaro
    15. Gabriela Burle
    16. Daniel Doro
    17. Jorge Kalil
    18. Edson Durigon
    19. Andrés Salazar
    20. Otávia Caballero
    21. Alexandre Machado
    22. João S. Silva
    23. Flávio da Fonseca
    24. Ana Paula Fernandes
    25. Santuza R. Teixeira
    26. Ricardo T. Gazzinelli

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  2. Synthetic multiantigen MVA vaccine COH04S1 protects against SARS-CoV-2 in Syrian hamsters and non-human primates

    1. Flavia Chiuppesi
    2. Vu H. Nguyen
    3. Yoonsuh Park
    4. Heidi Contreras
    5. Veronica Karpinski
    6. Katelyn Faircloth
    7. Jenny Nguyen
    8. Mindy Kha
    9. Daisy Johnson
    10. Joy Martinez
    11. Angelina Iniguez
    12. Qiao Zhou
    13. Teodora Kaltcheva
    14. Paul Frankel
    15. Swagata Kar
    16. Ankur Sharma
    17. Hanne Andersen
    18. Mark G. Lewis
    19. Yuriy Shostak
    20. Felix Wussow
    21. Don J. Diamond

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  3. Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display

    1. Shiho Tanaka
    2. C. Anders Olson
    3. Christopher O. Barnes
    4. Wendy Higashide
    5. Marcos Gonzalez
    6. Justin Taft
    7. Ashley Richardson
    8. Marta Martin-Fernandez
    9. Dusan Bogunovic
    10. Priyanthi N.P. Gnanapragasam
    11. Pamela J. Bjorkman
    12. Patricia Spilman
    13. Kayvan Niazi
    14. Shahrooz Rabizadeh
    15. Patrick Soon-Shiong

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. A model of preferential pairing between epithelial and dendritic cells in thymic antigen transfer

    1. Matouš Vobořil
    2. Jiří Březina
    3. Tomáš Brabec
    4. Jan Dobeš
    5. Ondřej Ballek
    6. Martina Dobešová
    7. Jasper Manning
    8. Richard S Blumberg
    9. Dominik Filipp

    • Curated by eLife

      Evaluation Summary:

      This manuscript will be of interest to immunologists studying mechanisms of thymic central tolerance. The study elegantly makes use of multiple genetic mouse models to generate data supporting the conclusion that different dendritic cell subsets in the thymus capture self-antigens from distinct subsets of thymic epithelial cells. However, some key conclusions are not entirely novel, and the final model, as currently presented, draws from only selective analyses and thus may not accurately reflect the antigen transfer between thymic epithelial cell and dendritic cell subsets that promote central tolerance.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 agreed to share their name with the authors.)

    Reviewed by eLife

    5 evaluationsAppears in 1 listLatest version Latest activity

  5. Design of T cell epitope-based vaccine candidate for SARS-CoV-2 targeting nucleocapsid and spike protein escape variants

    1. Gabriel Jabbour
    2. Samantha Rego
    3. Vincent Nguyenkhoa
    4. Sivanesan Dakshanamurthy

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. Immune recall improves antibody durability and breadth to SARS-CoV-2 variants

    1. Yuezhou Chen
    2. Pei Tong
    3. Noah Whiteman
    4. Ali Sanjari Moghaddam
    5. Mehrdad Zarghami
    6. Adam Zuiani
    7. Shaghayegh Habibi
    8. Avneesh Gautam
    9. Keerti
    10. Caihong Bi
    11. Tianshu Xiao
    12. Yongfei Cai
    13. Bing Chen
    14. Donna Neuberg
    15. Duane R. Wesemann

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  7. Intranasal administration of a VLP-based vaccine against COVID-19 induces neutralizing antibodies against SARS-CoV-2 and Variants of Concerns

    1. Dominik A. Rothen
    2. Pascal S. Krenger
    3. Aleksandra Nonic
    4. Ina Balke
    5. Anne-Cathrine S. Vogt
    6. Xinyue Chang
    7. Alessandro Manenti
    8. Fabio Vedovi
    9. Gunta Resevica
    10. Senta M. Walton
    11. Andris Zeltins
    12. Emanuele Montomoli
    13. Monique Vogel
    14. Martin F. Bachmann
    15. Mona O. Mohsen

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. A Thermostable Oral SARS-CoV-2 Vaccine Induces Mucosal and Protective Immunity

    1. Bertrand Bellier
    2. Alicia Saura
    3. Lucas A. Luján
    4. Cecilia R. Molina
    5. Hugo D. Luján
    6. David Klatzmann

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  9. SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans

    1. Philip A. Mudd
    2. Anastasia A. Minervina
    3. Mikhail V. Pogorelyy
    4. Jackson S. Turner
    5. Wooseob Kim
    6. Elizaveta Kalaidina
    7. Jan Petersen
    8. Aaron J. Schmitz
    9. Tingting Lei
    10. Alem Haile
    11. Allison M. Kirk
    12. Robert C. Mettelman
    13. Jeremy Chase Crawford
    14. Thi H.O. Nguyen
    15. Louise C. Rowntree
    16. Elisa Rosati
    17. Katherine A. Richards
    18. Andrea J. Sant
    19. Michael K. Klebert
    20. Teresa Suessen
    21. William D. Middleton
    22. Jeremie H. Estepp
    23. Stacey Schultz-Cherry
    24. Maureen A. McGargill
    25. Aditya Gaur
    26. James Hoffman
    27. Motomi Mori
    28. Li Tang
    29. Elaine Tuomanen
    30. Richard Webby
    31. Randall T. Hayden
    32. Hana Hakim
    33. Diego R. Hijano
    34. Kim J. Allison
    35. E. Kaitlynn Allen
    36. Resha Bajracharya
    37. Walid Awad
    38. Lee-Ann Van de Velde
    39. Brandi L. Clark
    40. Taylor L. Wilson
    41. Aisha Souquette
    42. Ashley Castellaw
    43. Ronald H. Dallas
    44. Ashleigh Gowen
    45. Thomas P. Fabrizio
    46. Chun-Yang Lin
    47. David C. Brice
    48. Sean Cherry
    49. Ericka Kirkpatrick Roubidoux
    50. Valerie Cortez
    51. Pamela Freiden
    52. Nicholas Wohlgemuth
    53. Kendall Whitt
    54. Joshua Wolf
    55. Sharlene A. Teefey
    56. Jane A. O’Halloran
    57. Rachel M. Presti
    58. Katherine Kedzierska
    59. Jamie Rossjohn
    60. Paul G. Thomas
    61. Ali H. Ellebedy

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  10. Targeted isolation of diverse human protective broadly neutralizing antibodies against SARS-like viruses

    1. Wan-ting He
    2. Rami Musharrafieh
    3. Ge Song
    4. Katharina Dueker
    5. Longping V. Tse
    6. David R. Martinez
    7. Alexandra Schäfer
    8. Sean Callaghan
    9. Peter Yong
    10. Nathan Beutler
    11. Jonathan L. Torres
    12. Reid M. Volk
    13. Panpan Zhou
    14. Meng Yuan
    15. Hejun Liu
    16. Fabio Anzanello
    17. Tazio Capozzola
    18. Mara Parren
    19. Elijah Garcia
    20. Stephen A. Rawlings
    21. Davey M. Smith
    22. Ian A. Wilson
    23. Yana Safonova
    24. Andrew B. Ward
    25. Thomas F. Rogers
    26. Ralph S. Baric
    27. Lisa E. Gralinski
    28. Dennis R. Burton
    29. Raiees Andrabi

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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