Immunology

SARS-CoV-2 mRNA-vaccine candidate; COReNAPCIN®, induces robust humoral and cellular immunity in mice and non-human primates

1. Reza Alimohammadi
2. Meysam Porgoo
3. Mohamad Eftekhary
4. Seyed Hossein Kiaie
5. Ehsan Ansari Dezfouli
6. Maryam Dehghani
7. Kaveh Nasrollahi
8. Talieh Malekshahabi
9. Maryam Heidari
10. Sedigheh Pouya
11. Masoumeh Alimohammadi
12. Dorsa Sattari Khavas
13. Mohammad Sadra Modaresi
14. Mohammad Hossein Ghasemi
15. Hamed Ramyar
16. Fatemeh Mohammadipour
17. Fateme Hamzelouei
18. Ahmadreza Mofayezi
19. Seyed Saeed Mottaghi
20. Amirhosein Rahmati
21. Mohsen Razzaznian
22. Vista Tirandazi
23. Mahdi Tat
24. Fatemeh Borzouee
25. Hossein Sadeghi
26. Melika Haji Mohammadi
27. Leila Rastegar
28. Seyed Milad Safar Sajadi
29. Hossein Ehsanbakhsh
30. Hamed Bazmbar
31. Zeinab Baghernejadan
32. Maedeh Shams Nouraei
33. Pouya Pazooki
34. Mina Pahlavanneshan
35. Khadijeh Alishah
36. Fateme Nasiri
37. Neda Mokhberian
38. Seyedeh Shima Mohammadi
39. Shima Akar
40. Hamidreza Niknam
41. Marzieh Azizi
42. Mohammad Ajoudanian
43. Mohammad Hossein Moteallehi-Ardakani
44. Seyed Ali Mousavi Shaegh
45. Reihaneh Ramezani
46. Vahid Salimi
47. Reza Moazzami
48. Seyed Mahmoud Hashemi
49. Somaye Dehghanizadeh
50. Vahid Khoddami

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Highly Thermotolerant SARS-CoV-2 Vaccine Elicits Neutralising Antibodies against Delta and Omicron in Mice

1. Petrus Jansen van Vuren
2. Alexander J. McAuley
3. Michael J. Kuiper
4. Nagendrakumar Balasubramanian Singanallur
5. Matthew P. Bruce
6. Shane Riddell
7. Sarah Goldie
8. Shruthi Mangalaganesh
9. Simran Chahal
10. Trevor W. Drew
11. Kim R. Blasdell
12. Mary Tachedjian
13. Leon Caly
14. Julian D. Druce
15. Shahbaz Ahmed
16. Mohammad Suhail Khan
17. Sameer Kumar Malladi
18. Randhir Singh
19. Suman Pandey
20. Raghavan Varadarajan
21. Seshadri S. Vasan

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Potent universal-coronavirus therapeutic activity mediated by direct respiratory administration of a Spike S2 domain-specific human neutralizing monoclonal antibody

1. Michael S. Piepenbrink
2. Jun-Gyu Park
3. Ashlesha Desphande
4. Andreas Loos
5. Chengjin Ye
6. Madhubanti Basu
7. Sanghita Sarkar
8. David Chauvin
9. Jennifer Woo
10. Philip Lovalenti
11. Nathaniel B. Erdmann
12. Paul A. Goepfert
13. Vu L. Truong
14. Richard A. Bowen
15. Mark R. Walter
16. Luis Martinez-Sobrido
17. James J. Kobie

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Soluble P2X7 receptor is elevated in the plasma of COVID-19 patients and correlates with disease severity

1. Julio García-Villalba
2. Laura Hurtado-Navarro
3. Alejandro Peñín-Franch
4. Cristina Molina-López
5. Laura Martínez-Alarcón
6. Diego Angosto-Bazarra
7. Alberto Baroja-Mazo
8. Pablo Pelegrín

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Soluble Signal Inhibitory Receptor on Leukocytes-1 Is Released from Activated Neutrophils by Proteinase 3 Cleavage

1. Helen J von Richthofen
2. Geertje H A Westerlaken
3. Doron Gollnast
4. Sjanna Besteman
5. Eveline M Delemarre
6. Karlijn Rodenburg
7. Petra Moerer
8. Daphne A C Stapels
9. Anand K Andiappan
10. Olaf Rötzschke
11. Stefan Nierkens
12. Helen L Leavis
13. Louis J Bont
14. Suzan H M Rooijakkers
15. Linde Meyaard

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Immunogenicity of an Ad26-based SARS-CoV-2 Omicron Vaccine in Naïve Mice and SARS-CoV-2 Spike Pre-immune Hamsters

1. Maarten Swart
2. Adriaan de Wilde
3. Sonja Schmit-Tillemans
4. Johan Verspuij
5. Chenandly Daal
6. Ying Choi
7. Aditya Perkasa
8. Eleni Kourkouta
9. Issam Tahiri
10. Michel Mulders
11. Ana Izquierdo Gil
12. Leacky Muchene
13. Jarek Juraszek
14. Jort Vellinga
15. Jerome Custers
16. Rinke Bos
17. Hanneke Schuitemaker
18. Frank Wegmann
19. Ramon Roozendaal
20. Harmjan Kuipers
21. Roland Zahn

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Antigen experience relaxes the organisational structure of the T cell receptor repertoire

1. Michal Mark
2. Shlomit Reich-Zeliger
3. Erez Greenstein
4. Dan Reshef
5. Asaf Madi
6. Benny Chain
7. Nir Friedman

• Curated by eLife

  Evaluation Summary:

  This study will be of interest for the fields of T cell immunology and computational biology. It represents a careful descriptive study of the T cell repertoires of young and old mice, quantifying the relationships between naive, regulatory, effector and memory subsets. It represents a first step and would benefit from additional analyses and interpretations.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #3 agreed to share their name with the authors.)

Reviewed by eLife

Immunological memory to Common Cold Coronaviruses assessed longitudinally over a three-year period

1. Esther Dawen Yu
2. Tara M. Narowski
3. Eric Wang
4. Emily Garrigan
5. Jose Mateus
6. April Frazier
7. Daniela Weiskopf
8. Alba Grifoni
9. Lakshmanane Premkumar
10. Ricardo da Silva Antunes
11. Alessandro Sette

Reviewed by ScreenIT

Intranasal Immunization with a Proteosome-Adjuvanted SARS-CoV2 Spike Protein-Based Vaccine is Immunogenic and Efficacious in Mice & Hamsters

1. Felicity C. Stark
2. Bassel Akache
3. Lise Deschatelets
4. Anh Tran
5. Matthew Stuible
6. Yves Durocher
7. Michael J. McCluskie
8. Gerard Agbayani
9. Renu Dudani
10. Blair A. Harrison
11. Tyler M. Renner
12. Shawn R. Makinen
13. Jegarubee Bavananthasivam
14. Diana Duque
15. Martin Gagne
16. Joseph Zimmermann
17. C. David Zarley
18. Terrence R. Cochrane
19. Martin Handfield

Reviewed by ScreenIT

Rapid Hypermutation B Cell Trajectory Recruits Previously Primed B Cells Upon Third SARS-Cov-2 mRNA Vaccination

1. Lisa Paschold
2. Bianca Klee
3. Cornelia Gottschick
4. Edith Willscher
5. Sophie Diexer
6. Christoph Schultheiß
7. Donjete Simnica
8. Daniel Sedding
9. Matthias Girndt
10. Michael Gekle
11. Rafael Mikolajczyk
12. Mascha Binder

Reviewed by ScreenIT