Immunology

  1. Omicron-specific and bivalent omicron-containing vaccine candidates elicit potent virus neutralisation in the animal model

    1. Asghar Abdoli
    2. Hamidreza Jamshidi
    3. Mohammad Taqavian
    4. Mehdi Lari Baghal
    5. Hasan Jalili

    Reviewed by ScreenIT

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  2. Redox regulation of PTPN22 affects the severity of T-cell-dependent autoimmune inflammation

    1. Jaime James
    2. Yifei Chen
    3. Clara M Hernandez
    4. Florian Forster
    5. Markus Dagnell
    6. Qing Cheng
    7. Amir A Saei
    8. Hassan Gharibi
    9. Gonzalo Fernandez Lahore
    10. Annika Åstrand
    11. Rajneesh Malhotra
    12. Bernard Malissen
    13. Roman A Zubarev
    14. Elias SJ Arnér
    15. Rikard Holmdahl

    • Curated by eLife

      Evaluation summary:

      This paper documents a novel aspect of how T cell activation is regulated by the PTPN22 phosphatase, namely reversible oxidation which transiently reduces the activity of PTPN22 to allow the T cell antigen receptor to drive a strong activation signal. This compelling work adds to our understanding of how an immune response is initiated and provides new insights that could be exploited for the development of new drugs to treat immune-mediated diseases.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 agreed to share their name with the authors.)

    Reviewed by eLife

    5 evaluationsAppears in 1 listLatest version Latest activity

  3. Milk of Cow and Goat, Immunized by Recombinant Protein Vaccine ZF-UZ-VAC2001(Zifivax), Contains Neutralizing Antibodies Against SARS-CoV-2 and Remains Active After Standard Milk Pasteurization

    1. Victoria Garib
    2. Stefani Katsamaki
    3. Shahlo Turdikulova
    4. Yuliya Levitskaya
    5. Nodira Zahidova
    6. Galina Bus
    7. Kristina Karamova
    8. Manona Rakhmedova
    9. Nigora Magbulova
    10. Alexander Bruhov
    11. Firuz Y. Garib
    12. Ibrokhim Y. Abdurakhmonov

    Reviewed by ScreenIT

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  4. Omicron-specific mRNA vaccination alone and as a heterologous booster against SARS-CoV-2

    1. Zhenhao Fang
    2. Lei Peng
    3. Renata Filler
    4. Kazushi Suzuki
    5. Andrew McNamara
    6. Qianqian Lin
    7. Paul A. Renauer
    8. Luojia Yang
    9. Bridget Menasche
    10. Angie Sanchez
    11. Ping Ren
    12. Qiancheng Xiong
    13. Madison Strine
    14. Paul Clark
    15. Chenxiang Lin
    16. Albert I. Ko
    17. Nathan D. Grubaugh
    18. Craig B. Wilen
    19. Sidi Chen

    Reviewed by ScreenIT

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  5. SARS-CoV-2-specific T cells associate with inflammation and reduced lung function in pulmonary post-acute sequalae of SARS-CoV-2

    1. Katherine M. Littlefield
    2. Renée O. Watson
    3. Jennifer M. Schneider
    4. Charles P. Neff
    5. Eiko Yamada
    6. Min Zhang
    7. Thomas B. Campbell
    8. Michael T. Falta
    9. Sarah E. Jolley
    10. Andrew P. Fontenot
    11. Brent E. Palmer

    Reviewed by ScreenIT

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  6. Dam–Infant Rhesus Macaque Pairs to Dissect Age-Dependent Responses to SARS-CoV-2 Infection

    1. Stephanie N Langel
    2. Carolina Garrido
    3. Caroline Phan
    4. Tatianna Travieso
    5. Helene Kirshner
    6. Todd DeMarco
    7. Zhong-Min Ma
    8. J Rachel Reader
    9. Katherine J Olstad
    10. Rebecca L Sammak
    11. Yashavanth Shaan Lakshmanappa
    12. Jamin W Roh
    13. Jennifer Watanabe
    14. Jodie Usachenko
    15. Ramya Immareddy
    16. Rachel Pollard
    17. Smita S Iyer
    18. Sallie Permar
    19. Lisa A Miller
    20. Koen K A Van Rompay
    21. Maria Blasi

    Reviewed by ScreenIT

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  7. Next-generation intranasal Covid-19 vaccine: a polymersome-based protein subunit formulation that provides robust protection against multiple variants of concern and early reduction in viral load of the upper airway in the golden Syrian hamster model

    1. Jian Hang Lam
    2. Devendra Shivhare
    3. Teck Wan Chia
    4. Suet Li Chew
    5. Gaurav Sinsinbar
    6. Ting Yan Aw
    7. Siamy Wong
    8. Shrinivas Venkatraman
    9. Francesca Wei Inng Lim
    10. Pierre Vandepapeliere
    11. Madhavan Nallani

    Reviewed by ScreenIT

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  8. Lyophilized mRNA-lipid nanoparticle vaccines with long-term stability and high antigenicity against SARS-CoV-2

    1. Liangxia Ai
    2. Yafei Li
    3. Li Zhou
    4. Wenrong Yao
    5. Hao Zhang
    6. Zhaoyu Hu
    7. Jinyu Han
    8. Weijie Wang
    9. Junmiao Wu
    10. Pan Xu
    11. Ruiyue Wang
    12. Zhangyi Li
    13. Zhouwang Li
    14. Chengliang Wei
    15. Jianqun Liang
    16. Haobo Chen
    17. Zhimiao Yang
    18. Ming Guo
    19. Zhixiang Huang
    20. Xin Wang
    21. Zhen Zhang
    22. Wenjie Xiang
    23. Dazheng Sun
    24. Lianqiang Xu
    25. Meiyan Huang
    26. Bin Lv
    27. Peiqi Peng
    28. Shangfeng Zhang
    29. Xuhao Ji
    30. Huiyi Luo
    31. Nanping Chen
    32. Jianping Chen
    33. Ke Lan
    34. Yong Hu

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  9. Epigenetic memory of coronavirus infection in innate immune cells and their progenitors

    1. Jin-Gyu Cheong
    2. Arjun Ravishankar
    3. Siddhartha Sharma
    4. Christopher N. Parkhurst
    5. Simon A. Grassmann
    6. Claire K. Wingert
    7. Paoline Laurent
    8. Sai Ma
    9. Lucinda Paddock
    10. Isabella C. Miranda
    11. Emin Onur Karakaslar
    12. Djamel Nehar-Belaid
    13. Asa Thibodeau
    14. Michael J. Bale
    15. Vinay K. Kartha
    16. Jim K. Yee
    17. Minh Y. Mays
    18. Chenyang Jiang
    19. Andrew W. Daman
    20. Alexia Martinez de Paz
    21. Dughan Ahimovic
    22. Victor Ramos
    23. Alexander Lercher
    24. Erik Nielsen
    25. Sergio Alvarez-Mulett
    26. Ling Zheng
    27. Andrew Earl
    28. Alisha Yallowitz
    29. Lexi Robbins
    30. Elyse LaFond
    31. Karissa L. Weidman
    32. Sabrina Racine-Brzostek
    33. He S. Yang
    34. David R. Price
    35. Louise Leyre
    36. André F. Rendeiro
    37. Hiranmayi Ravichandran
    38. Junbum Kim
    39. Alain C. Borczuk
    40. Charles M. Rice
    41. R. Brad Jones
    42. Edward J. Schenck
    43. Robert J. Kaner
    44. Amy Chadburn
    45. Zhen Zhao
    46. Virginia Pascual
    47. Olivier Elemento
    48. Robert E. Schwartz
    49. Jason D. Buenrostro
    50. Rachel E. Niec
    51. Franck J. Barrat
    52. Lindsay Lief
    53. Joseph C. Sun
    54. Duygu Ucar
    55. Steven Z. Josefowicz

    Reviewed by ScreenIT

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  10. Auto-immunoproteomics analysis of COVID-19 ICU patients revealed increased levels of autoantibodies related to the male reproductive system

    1. Frank Schmidt
    2. Houari B. Abdesselem
    3. Karsten Suhre
    4. Nishant N. Vaikath
    5. Muhammad U. Sohail
    6. Maryam Al-Nesf
    7. Ilham Bensmail
    8. Fathima Mashod
    9. Hina Sarwath
    10. Joerg Bernhardt
    11. Stephanie Schaefer-Ramadan
    12. Ti-Myen Tan
    13. Priscilla E. Morris
    14. Edward J. Schenck
    15. David Price
    16. Vidya Mohamed-Ali
    17. Mohammed Al-Maadheed
    18. Abdelilah Arredouani
    19. Julie Decock
    20. Jonathan M. Blackburn
    21. Augustine M. K. Choi
    22. Omar M. El-Agnaf

    Reviewed by ScreenIT

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