Bioengineering

  1. Targeting sex determination to suppress mosquito populations

    1. Ming Li
    2. Nikolay P Kandul
    3. Ruichen Sun
    4. Ting Yang
    5. Elena D Benetta
    6. Daniel J Brogan
    7. Igor Antoshechkin
    8. Héctor M Sánchez C
    9. Yinpeng Zhan
    10. Nicolas A DeBeaubien
    11. YuMin M Loh
    12. Matthew P Su
    13. Craig Montell
    14. John M Marshall
    15. Omar S Akbari

    • Curated by eLife

      eLife assessment

      This valuable paper builds on a method, previously conceptualized and validated, of genetic control for insect populations. The method, called pgSIT, uses integrated CRISPR-Cas9 based constructs to generate, in certain combinations of genotypes, mutations that cause both male sterility and female inviability. Release of such genotypes in sufficiently large numbers can lead to an inundation of a local insect population with sterile males and this can lead to localised population suppression, which represents an effective method of control for problematic insect populations. The data are convincing and will be of interest to anyone working on vector control strategies.

    Reviewed by eLife

    9 evaluationsAppears in 1 listLatest version Latest activity

  2. Synergistic induction of blood-brain barrier properties

    1. Gergő Porkoláb
    2. Mária Mészáros
    3. Anikó Szecskó
    4. Judit P. Vigh
    5. Fruzsina R. Walter
    6. Ricardo Figueiredo
    7. Ildikó Kálomista
    8. Zsófia Hoyk
    9. Gaszton Vizsnyiczai
    10. Ilona Gróf
    11. Jeng-Shiung Jan
    12. Fabien Gosselet
    13. Melinda K. Pirity
    14. Monika Vastag
    15. Natalie Hudson
    16. Matthew Campbell
    17. Szilvia Veszelka
    18. Mária A. Deli

    Reviewed by PREreview

    1 evaluationAppears in 2 listsLatest version Latest activity

  3. Delivery Strategies for Skin: Comparison of Nanoliter Jets, Needles and Topical Solutions

    1. Katharina Cu
    2. Ruchi Bansal
    3. Samir Mitragotri
    4. David Fernandez Rivas

    Reviewed by PREreview

    1 evaluationAppears in 1 listLatest version Latest activity

  4. Two-Photon Targeted, Quad Whole-Cell Patch-Clamping Robot

    1. Gema I Vera Gonzalez
    2. Phatsimo O Kgwarae
    3. Simon R Schultz

    Reviewed by Arcadia Science

    2 evaluationsAppears in 1 listLatest version Latest activity

  5. Zero-shot learning enables instant denoising and super-resolution in optical fluorescence microscopy

    1. Chang Qiao
    2. Yunmin Zeng
    3. Quan Meng
    4. Xingye Chen
    5. Haoyu Chen
    6. Tao Jiang
    7. Rongfei Wei
    8. Jiabao Guo
    9. Wenfeng Fu
    10. Huaide Lu
    11. Di Li
    12. Yuwang Wang
    13. Hui Qiao
    14. Jiamin Wu
    15. Dong Li
    16. Qionghai Dai

    Reviewed by Arcadia Science

    1 evaluationAppears in 1 listLatest version Latest activity

  6. Molecular de-extinction of antibiotics enabled by deep learning

    1. Fangping Wan
    2. Marcelo D. T. Torres
    3. Jacqueline Peng
    4. Cesar de la Fuente-Nunez

    Reviewed by Arcadia Science

    1 evaluationAppears in 1 listLatest version Latest activity

  7. Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors

    1. Lampros Mavrommatis
    2. Hyun-Woo Jeong
    3. Urs Kindler
    4. Gemma Gomez-Giro
    5. Marie-Cecile Kienitz
    6. Martin Stehling
    7. Olympia E Psathaki
    8. Dagmar Zeuschner
    9. M Gabriele Bixel
    10. Dong Han
    11. Gabriela Morosan-Puopolo
    12. Daniela Gerovska
    13. Ji Hun Yang
    14. Jeong Beom Kim
    15. Marcos J Arauzo-Bravo
    16. Jens C Schwamborn
    17. Stephan A Hahn
    18. Ralf H Adams
    19. Hans R Schöler
    20. Matthias Vorgerd
    21. Beate Brand-Saberi
    22. Holm Zaehres

    • Curated by eLife

      eLife assessment

      The authors develop a cell culture system for studies of muscle tissue development and homeostasis. They convincingly validate a novel 3D cell model. Their thorough molecular and functional characterization will make this useful for future workers in the field.

    Reviewed by eLife

    7 evaluationsAppears in 1 listLatest version Latest activity

  8. Acidic nanoparticles restore lysosomal acidification and rescue metabolic dysfunction in pancreatic β-cells under lipotoxic condition

    1. Chih Hung Lo
    2. Lance M. O’Connor
    3. Gavin Wen Zhao Loi
    4. Eka Norfaishanty Saipuljumri
    5. Jonathan Indajang
    6. Kaitlynn M. Lopes
    7. Orian S. Shirihai
    8. Mark W. Grinstaff
    9. Jialiu Zeng

    Reviewed by PREreview

    1 evaluationAppears in 2 listsLatest version Latest activity

  9. Production of extracellular polymeric substances in granular sludge under selection for Accumulibacter and Competibacter

    1. Lorena B. Guimarães
    2. Nina R. Gubser
    3. Yuemei Lin
    4. Jure Zlópasa
    5. Simon Felz
    6. Sergio Tomás Martínez
    7. Mario Pronk
    8. Thomas R. Neu
    9. Morten K. D. Dueholm
    10. Mads Albertsen
    11. Rejane H. R. da Costa
    12. Per Halkjær Nielsen
    13. Mark C. M. van Loosdrecht
    14. David G. Weissbrodt

    Reviewed by Arcadia Science

    15 evaluationsAppears in 1 listLatest version Latest activity

  10. Bio-friendly long-term subcellular dynamic recording by self-supervised image enhancement microscopy

    1. Guoxun Zhang
    2. Xiaopeng Li
    3. Yuanlong Zhang
    4. Xiaofei Han
    5. Xinyang Li
    6. Jinqiang Yu
    7. Boqi Liu
    8. Jiamin Wu
    9. Li Yu
    10. Qionghai Dai

    Reviewed by Arcadia Science

    101 evaluationsAppears in 1 listLatest version Latest activity
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