Bioengineering

  1. Automated cell annotation in multi-cell images using an improved CRF_ID algorithm

    1. Hyun Jee Lee
    2. Jingting Liang
    3. Shivesh Chaudhary
    4. Sihoon Moon
    5. Zikai Yu
    6. Taihong Wu
    7. He Liu
    8. Myung-Kyu Choi
    9. Yun Zhang
    10. Hang Lu

    • Curated by eLife

      eLife Assessment

      This Research Advance describes a valuable image analysis method to identify individual neurons within a ‎population of fluorescently labeled cells in the nematode C. elegans. The findings are solid and the method succeeds to identify cells with high precision. The method will be be of interest to the C. elegans research community.

    Reviewed by eLife

    11 evaluationsAppears in 1 listLatest version Latest activity

  2. Endo-Lysosome-Targeted Nanoparticle Delivery of Antiviral Therapy for Coronavirus Infections

    1. Anton Petcherski
    2. Brett M Tingley
    3. Andrew Martin
    4. Sarah Adams
    5. Alexandra J Brownstein
    6. Ross A Steinberg
    7. Byourak Shabane
    8. Jennifer Ngo
    9. Corey Osto
    10. Gustavo Garcia
    11. Michaela Veliova
    12. Vaithilingaraja Arumugaswami
    13. Aaron H Colby
    14. Orian S Shirihai
    15. Mark W Grinstaff

    Reviewed by Review Commons

    6 evaluationsAppears in 1 listLatest version Latest activity

  3. The vascularised chamber device significantly enhances the survival of transplanted liver organoids

    1. Denis D. Shi
    2. Evelyn Makris
    3. Yi-Wen Gerrand
    4. Pu-Han Lo
    5. George C. Yeoh
    6. Wayne A. Morrison
    7. Geraldine M. Mitchell
    8. Kiryu K. Yap

    • Curated by eLife

      eLife assessment

      This solid manuscript describes a preclinical model to assess different methods of infusion of organoids for clinical applications. This is an important and timely study with practical implications beyond a single subfield. The methods described, including the analysis, broadly support the claims although there are some areas for improvement.

    Reviewed by eLife

    3 evaluationsAppears in 1 listLatest version Latest activity

  4. Technical upgrade of an open-source liquid handler to support bacterial colony screening

    1. Irene del Olmo
    2. Pablo Yubero
    3. Álvaro Gómez-Luengo
    4. Juan Nogales
    5. David R. Espeso

    Reviewed by Arcadia Science

    3 evaluationsAppears in 1 listLatest version Latest activity

  5. Targeting sex determination to suppress mosquito populations

    1. Ming Li
    2. Nikolay P Kandul
    3. Ruichen Sun
    4. Ting Yang
    5. Elena D Benetta
    6. Daniel J Brogan
    7. Igor Antoshechkin
    8. Héctor M Sánchez C
    9. Yinpeng Zhan
    10. Nicolas A DeBeaubien
    11. YuMin M Loh
    12. Matthew P Su
    13. Craig Montell
    14. John M Marshall
    15. Omar S Akbari

    • Curated by eLife

      eLife assessment

      This valuable paper builds on a method, previously conceptualized and validated, of genetic control for insect populations. The method, called pgSIT, uses integrated CRISPR-Cas9 based constructs to generate, in certain combinations of genotypes, mutations that cause both male sterility and female inviability. Release of such genotypes in sufficiently large numbers can lead to an inundation of a local insect population with sterile males and this can lead to localised population suppression, which represents an effective method of control for problematic insect populations. The data are convincing and will be of interest to anyone working on vector control strategies.

    Reviewed by eLife

    9 evaluationsAppears in 1 listLatest version Latest activity

  6. Synergistic induction of blood–brain barrier properties

    1. Gergő Porkoláb
    2. Mária Mészáros
    3. Anikó Szecskó
    4. Judit P. Vigh
    5. Fruzsina R. Walter
    6. Ricardo Figueiredo
    7. Ildikó Kálomista
    8. Zsófia Hoyk
    9. Gaszton Vizsnyiczai
    10. Ilona Gróf
    11. Jeng-Shiung Jan
    12. Fabien Gosselet
    13. Melinda K. Pirity
    14. Monika Vastag
    15. Natalie Hudson
    16. Matthew Campbell
    17. Szilvia Veszelka
    18. Mária A. Deli

    Reviewed by PREreview

    1 evaluationAppears in 2 listsLatest version Latest activity

  7. Delivery Strategies for Skin: Comparison of Nanoliter Jets, Needles and Topical Solutions

    1. Katharina Cu
    2. Ruchi Bansal
    3. Samir Mitragotri
    4. David Fernandez Rivas

    Reviewed by PREreview

    1 evaluationAppears in 1 listLatest version Latest activity

  8. Two-Photon Targeted, Quad Whole-Cell Patch-Clamping Robot

    1. Gema I Vera Gonzalez
    2. Phatsimo O Kgwarae
    3. Simon R Schultz

    Reviewed by Arcadia Science

    2 evaluationsAppears in 1 listLatest version Latest activity

  9. Zero-shot learning enables instant denoising and super-resolution in optical fluorescence microscopy

    1. Chang Qiao
    2. Yunmin Zeng
    3. Quan Meng
    4. Xingye Chen
    5. Haoyu Chen
    6. Tao Jiang
    7. Rongfei Wei
    8. Jiabao Guo
    9. Wenfeng Fu
    10. Huaide Lu
    11. Di Li
    12. Yuwang Wang
    13. Hui Qiao
    14. Jiamin Wu
    15. Dong Li
    16. Qionghai Dai

    Reviewed by Arcadia Science

    1 evaluationAppears in 1 listLatest version Latest activity

  10. Deep-learning-enabled antibiotic discovery through molecular de-extinction

    1. Fangping Wan
    2. Marcelo D. T. Torres
    3. Jacqueline Peng
    4. Cesar de la Fuente-Nunez

    Reviewed by Arcadia Science

    1 evaluationAppears in 1 listLatest version Latest activity
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