Bioengineering

  1. Stable nebulization and muco‐trapping properties of regdanvimab/ IN ‐006 support its development as a potent, dose‐saving inhaled therapy for COVID ‐19

    1. Morgan D. McSweeney
    2. Ian Stewart
    3. Zach Richardson
    4. Hyunah Kang
    5. Yoona Park
    6. Cheolmin Kim
    7. Karthik Tiruthani
    8. Whitney Wolf
    9. Alison Schaefer
    10. Priya Kumar
    11. Harendra Aurora
    12. Jeff Hutchins
    13. Jong Moon Cho
    14. Anthony J. Hickey
    15. Soo Young Lee
    16. Samuel K. Lai

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  2. Modular capsid decoration boosts adenovirus vaccine-induced humoral immunity against SARS-CoV-2

    1. Matthew D.J. Dicks
    2. Louisa M. Rose
    3. Rebecca A. Russell
    4. Lesley A.H. Bowman
    5. Carl Graham
    6. Jose M. Jimenez-Guardeño
    7. Katie J. Doores
    8. Michael H. Malim
    9. Simon J. Draper
    10. Mark Howarth
    11. Sumi Biswas

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  3. Mosaic receptor-binding domain nanoparticles induce protective immunity against SARS-CoV-2 challenges

    1. Dan Bi Lee
    2. Hyojin Kim
    3. Ju Hwan Jeong
    4. Ui soon Jang
    5. You Yeon Chang
    6. Seokbeom Roh
    7. Hyunbum Jeon
    8. Eun Jeong Kim
    9. Su Yeon Han
    10. Jin Young Maeng
    11. Stefan Magez
    12. Magdalena Radwanska
    13. Ji Young Mun
    14. Hyun Sik Jun
    15. Gyudo Lee
    16. Min-Suk Song
    17. Hye-Ra Lee
    18. Mi Sook Chung
    19. Yun Hee Baek
    20. Kyung Hyun Kim

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. Biomechanical Dependence of SARS-CoV-2 Infections

    1. Alexandra Paul
    2. Sachin Kumar
    3. Tamer S. Kaoud
    4. Madison R. Pickett
    5. Amanda L. Bohanon
    6. Janet Zoldan
    7. Kevin N. Dalby
    8. Sapun H. Parekh

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  5. Engineering defensin α‐helix to produce high‐affinity SARS‐CoV ‐2 spike protein binding ligands

    1. Leonardo Antônio Fernandes
    2. Anderson Albino Gomes
    3. Beatriz Gomes Guimarães
    4. Maria de Lourdes Borba Magalhães
    5. Partha Ray
    6. Gustavo Felippe da Silva

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. Preclinical Establishment of a Divalent Vaccine against SARS-CoV-2

    1. Zsofia Hevesi
    2. Daniela Anna Gerges
    3. Sebastian Kapps
    4. Raimundo Freire
    5. Sophie Schmidt
    6. Daniela D. Pollak
    7. Klaus Schmetterer
    8. Tobias Frey
    9. Rita Lang
    10. Wolfgang Winnicki
    11. Alice Schmidt
    12. Tibor Harkany
    13. Ludwig Wagner

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  7. Human cardiac organoids to model COVID‐19 cytokine storm induced cardiac injuries

    1. Dimitrios C. Arhontoulis
    2. Charles M. Kerr
    3. Dylan Richards
    4. Kelsey Tjen
    5. Nathaniel Hyams
    6. Jefferey A. Jones
    7. Kristine Deleon‐Pennell
    8. Donald Menick
    9. Hanna Bräuninger
    10. Diana Lindner
    11. Dirk Westermann
    12. Ying Mei

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. Genetically engineered insects with sex-selection and genetic incompatibility enable population suppression

    1. Ambuj Upadhyay
    2. Nathan R Feltman
    3. Adam Sychla
    4. Anna Janzen
    5. Siba R Das
    6. Maciej Maselko
    7. Michael Smanski

    • Curated by eLife

      Evaluation Summary:

      This paper is of interest to entomologists caring for genetic pest control or molecular biologists following synthetic biology. The authors describe a fruit fly strain that combines constructs that establish both repressible female-lethality and genetic incompatibility based on CRISPR transactivation. They show that this strain has high penetrance for these two traits and that it can suppress wild-type flies when released into cycling cage populations. The paper is thus a neat technology demonstration for a genetic control strategy possibly applicable to other insects including pests or disease vectors.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 agreed to share their name with the authors.)

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity

  9. Nanoformulated Remdesivir with Extremely Low Content of Poly(2‐oxazoline)‐Based Stabilizer for Aerosol Treatment of COVID‐19

    1. Jacob D. Ramsey
    2. Ian E. Stewart
    3. Emily A. Madden
    4. Chaemin Lim
    5. Duhyeong Hwang
    6. Mark T. Heise
    7. Anthony J. Hickey
    8. Alexander V. Kabanov

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  10. Targeting SARS-CoV-2 infection through CAR-T like bispecific T cell engagers incorporating ACE2

    1. Mikail Dogan
    2. Lina Kozhaya
    3. Lindsey Placek
    4. Fatih Karabacak
    5. Mesut Yigit
    6. Derya Unutmaz

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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