HHMI Transparent and Accountable Peer Review Training Pilot PREreviews

Structural basis for CCR6 modulation by allosteric antagonists

1. David Jonathan Wasilko
2. Brian S. Gerstenberger
3. Kathleen A. Farley
4. Wei Li
5. Jennifer Alley
6. Mark E. Schnute
7. Ray J. Unwalla
8. Jorge Victorino
9. Kimberly K. Crouse
10. Ru Ding
11. Parag V. Sahasrabudhe
12. Fabien Vincent
13. Richard K. Frisbie
14. Alpay Dermenci
15. Andrew Flick
16. Chulho Choi
17. Gary Chinigo
18. James J. Mousseau
19. John I. Trujillo
20. Philippe Nuhant
21. Prolay Mondal
22. Vincent Lombardo
23. Daniel Lamb
24. Barbara J. Hogan
25. Gurdeep Singh Minhas
26. Elena Segala
27. Christine Oswald
28. Ian W. Windsor
29. Seungil Han
30. Mathieu Rappas
31. Robert M. Cooke
32. Matthew F. Calabrese
33. Gabriel Berstein
34. Atli Thorarensen
35. Huixian Wu

Reviewed by PREreview

REL2 overexpression in the Anopheles gambiae midgut causes major transcriptional changes but fails to induce an immune response

1. Astrid Hoermann
2. Paolo Capriotti
3. Giuseppe Del Corsano
4. Maria Grazia Inghilterra
5. Tibebu Habtewold
6. Julia A. Cai
7. Gauri Sachiko Saini
8. Huong Nguyen
9. Nikolai Windbichler
10. George K. Christophides

Reviewed by PREreview

Mitochondrial ATP synthesis is essential for efficient gametogenesis in Plasmodium falciparum

1. Penny C Sparkes
2. Mufuliat Toyin Famodimu
3. Eduardo Alves
4. Eric Springer
5. Jude Przyborski
6. Michael J Delves

Reviewed by PREreview

Newly synthesized mRNA selectively escapes translational repression following acute stress

1. Mostafa Zedan
2. Alexandra P. Schürch
3. Stephanie Heinrich
4. Pablo Aurelio Gómez García
5. Sarah Khawaja
6. Karsten Weis

Reviewed by PREreview

Aging represses lung tumorigenesis and alters tumor suppression

1. Emily G. Shuldiner
2. Saswati Karmakar
3. Min K. Tsai
4. Jess D. Hebert
5. Yuning J. Tang
6. Laura Andrejka
7. Minwei Wang
8. Colin R. Detrick
9. Hongchen Cai
10. Rui Tang
11. Dmitri A. Petrov
12. Monte M. Winslow

Reviewed by PREreview

Potential pandemic risk of circulating swine H1N2 influenza viruses

1. Valerie Le Sage
2. Nicole C. Rockey
3. Kevin R. McCarthy
4. Andrea J. French
5. Meredith J. Shephard
6. Ryan McBride
7. Jennifer E. Jones
8. Sydney G. Walter
9. Joshua D. Doyle
10. Lingqing Xu
11. Dominique J. Barbeau
12. Shengyang Wang
13. Sheila A. Frizzell
14. Lora H. Rigatti
15. Michael M. Myerburg
16. James C. Paulson
17. Anita K. McElroy
18. Tavis K. Anderson
19. Amy L. Vincent Baker
20. Seema S. Lakdawala

Reviewed by PREreview

Indels allow antiviral proteins to evolve functional novelty inaccessible by missense mutations

1. Jeannette L. Tenthorey
2. Serena del Banco
3. Ishrak Ramzan
4. Hayley Klingenberg
5. Chang Liu
6. Michael Emerman
7. Harmit S. Malik

Reviewed by PREreview

Cryo-EM structure and biochemical analysis of human chemokine receptor CCR8

1. Qi Peng
2. Haihai Jiang
3. Xinyu Cheng
4. Na Wang
5. Sili Zhou
6. Yuting Zhang
7. Tingting Yang
8. Yixiang Chen
9. Wei Zhang
10. Sijia Lv
11. Weiwei Nan
12. JianFei Wang
13. Guo-Huang Fan
14. Jian Li
15. Jin Zhang

Reviewed by PREreview

Genetic architecture of inbreeding depression may explain its persistence in a population of wild red deer

1. Anna M. Hewett
2. Susan E. Johnston
3. Alison Morris
4. Sean Morris
5. Josephine M. Pemberton

Reviewed by PREreview

Unraveling the genetic legacy of commercial whaling in bowhead whales and narwhals

1. Evelien de Greef
2. Claudio Müller
3. Matt J. Thorstensen
4. Steven H. Ferguson
5. Cortney A. Watt
6. Marianne Marcoux
7. Stephen D. Petersen
8. Colin J. Garroway

Reviewed by PREreview

Deep mutational scanning reveals functional constraints and antigenic variability of Lassa virus glycoprotein complex

1. Caleb R. Carr
2. Katharine H. D. Crawford
3. Michael Murphy
4. Jared G. Galloway
5. Hugh K. Haddox
6. Frederick A. Matsen
7. Kristian G. Andersen
8. Neil P. King
9. Jesse D. Bloom

Reviewed by PREreview

Divergent mechanisms of steroid inhibition in the human ρ1 GABA _A receptor

1. Chen Fan
2. John Cowgill
3. Rebecca J. Howard
4. Erik Lindahl

Reviewed by PREreview

Full-length direct RNA sequencing uncovers stress-granule dependent RNA decay upon cellular stress

1. Showkat A. Dar
2. Sulochan Malla
3. Vlastimil Martinek
4. Matthew J. Payea
5. Christopher T. Lee
6. Jessica Martin
7. Aditya J. Khandeshi
8. Jennifer L. Martindale
9. Cedric Belair
10. Manolis Maragkakis

• Curated by eLife

  eLife assessment

  This valuable study describes mRNA shortening during cellular stress and interestingly observes that this shortening is dependent on localization in stress granules. Surprisingly, this mRNA shortening does not appear to require the shortening of polyA tails. These are in principle novel findings, but the evidence for them is currently incomplete. Additional experiments would help bolster confidence in how the authors interpret their data.

Reviewed by PREreview, eLife

Cytoplasmic protein-free mRNA induces stress granules by two G3BP1/2-dependent mechanisms

1. Sean J. Ihn
2. Laura Farlam-Williams
3. Alexander F. Palazzo
4. Hyun O. Lee

Reviewed by PREreview

Virion morphology and on-virus spike protein structures of diverse SARS-CoV-2 variants

1. Zunlong Ke
2. Thomas P. Peacock
3. Jonathan C. Brown
4. Carol M. Sheppard
5. Tristan I. Croll
6. Abhay Kotecha
7. Daniel H. Goldhill
8. Wendy S. Barclay
9. John A.G. Briggs

Reviewed by PREreview