eLife

Latest preprint reviews

1. We couldn't get details of this article at this time:
   10.1101/2021.10.25.465687

2. We couldn't get details of this article at this time:
   10.1101/2023.03.10.532069

3. An in vitro model for vitamin A transport across the human blood–brain barrier

   This article has 2 authors:

   1. Chandler B Est
   2. Regina M Murphy

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This fundamental work substantially advances our understanding of retinol transport through the blood-brain barrier. The evidence supporting the conclusions is compelling, with rigorous biochemical assays. In general, the work is of broad interest to cell biologists, biochemists and neuroscientists.

   Reviewed by eLife

4. Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization

   This article has 65 authors:

   1. Van Thien Chi Nguyen
   2. Trong Hieu Nguyen
   3. Nhu Nhat Tan Doan
   4. Thi Mong Quynh Pham
   5. Giang Thi Huong Nguyen
   6. Thanh Dat Nguyen
   7. Thuy Thi Thu Tran
   8. Duy Long Vo
   9. Thanh Hai Phan
   10. Thanh Xuan Jasmine
   11. Van Chu Nguyen
   12. Huu Thinh Nguyen
   13. Trieu Vu Nguyen
   14. Thi Hue Hanh Nguyen
   15. Le Anh Khoa Huynh
   16. Trung Hieu Tran
   17. Quang Thong Dang
   18. Thuy Nguyen Doan
   19. Anh Minh Tran
   20. Viet Hai Nguyen
   21. Vu Tuan Anh Nguyen
   22. Le Minh Quoc Ho
   23. Quang Dat Tran
   24. Thi Thu Thuy Pham
   25. Tan Dat Ho
   26. Bao Toan Nguyen
   27. Thanh Nhan Vo Nguyen
   28. Thanh Dang Nguyen
   29. Dung Thai Bieu Phu
   30. Boi Hoan Huu Phan
   31. Thi Loan Vo
   32. Thi Huong Thoang Nai
   33. Thuy Trang Tran
   34. My Hoang Truong
   35. Ngan Chau Tran
   36. Trung Kien Le
   37. Thanh Huong Thi Tran
   38. Minh Long Duong
   39. Hoai Phuong Thi Bach
   40. Van Vu Kim
   41. The Anh Pham
   42. Duc Huy Tran
   43. Trinh Ngoc An Le
   44. Truong Vinh Ngoc Pham
   45. Minh Triet Le
   46. Dac Ho Vo
   47. Thi Minh Thu Tran
   48. Minh Nguyen Nguyen
   49. Thi Tuong Vi Van
   50. Anh Nhu Nguyen
   51. Thi Trang Tran
   52. Vu Uyen Tran
   53. Minh Phong Le
   54. Thi Thanh Do
   55. Thi Van Phan
   56. Hong-Dang Luu Nguyen
   57. Duy Sinh Nguyen
   58. Van Thinh Cao
   59. Thanh-Thuy Thi Do
   60. Dinh Kiet Truong
   61. Hung Sang Tang
   62. Hoa Giang
   63. Hoai-Nghia Nguyen
   64. Minh-Duy Phan
   65. Le Son Tran

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This study provides insights into the early detection of malignancies with noninvasive methods by developing a framework, which assesses methylation, CNA, and other genomic features. They established a solid model in discriminating malignancies from healthy controls, as well as the ability to distinguish tumor of origin. This important study will demonstrate its practical impacts in the clinic and other researchers of the field.

   Reviewed by eLife

5. We couldn't get details of this article at this time:
   10.1101/2022.07.02.498564

6. Context-Aware Amino Acid Embedding Advances Analysis of TCR-Epitope Interactions

   This article has 4 authors:

   1. Pengfei Zhang
   2. Seojin Bang
   3. Michael Cai
   4. Heewook Lee

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This study provides an important tool for predicting binding between immune cells receptors and antigens based on protein sequence data. The analysis convincingly showed the tool's effectiveness in both supervised TCR binding prediction and unsupervised clustering, surpassing existing methods in accuracy and reducing annotation costs. This study will be of interest to immunologists and computational biologists.

   Reviewed by eLife

7. We couldn't get details of this article at this time:
   10.1101/2023.05.24.542083

8. We couldn't get details of this article at this time:
   10.1101/2022.10.24.513503

9. Regulation of store-operated Ca2+ entry by IP3 receptors independent of their ability to release Ca2+

   This article has 8 authors:

   1. Pragnya Chakraborty
   2. Bipan Kumar Deb
   3. Vikas Arige
   4. Thasneem Musthafa
   5. Sundeep Malik
   6. David I Yule
   7. Colin W Taylor
   8. Gaiti Hasan

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     In this manuscript, Chakraborty et al address the role of IP3R1 in regulating store-operated calcium entry in neurons and neural progenitors. Long-standing observations in non-neuronal cells have shown that IP3Rs are not required for SOCE. In contrast to those findings, this manuscript determines that in neuronal cells, knockdown of IP3R1 suppresses SOCE by disrupting ER-plasma membrane contact sites. The paper supports a novel role for IP3R1 as a tether in promoting membrane contact sites which would have broad implications for a range of physiological processes including SOCE and lipid metabolism.

   Reviewed by eLife

10. We couldn't get details of this article at this time:
    10.1101/2023.04.04.535463