eLife

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1. We couldn't get details of this article at this time:
   10.1101/2023.02.09.527927

2. We couldn't get details of this article at this time:
   10.1101/2023.07.21.550081

3. Opposing chemosensory functions of closely related gustatory receptors

   This article has 2 authors:

   1. Ji-Eun Ahn
   2. Hubert Amrein

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This valuable study focuses on the role of the Gr28 family of insect chemoreceptors. Using the Drosophila larva, the authors show that taste neurons expressing different members of this family of bitter taste receptors trigger opposite behavior – attraction and repulsion. They establish the minimal bitter taste receptor subunit composition needed in these neurons to mediate the repulsion of bitter tastants. The evidence presented is convincing, using well-validated and controlled tools and experiments.

   Reviewed by eLife

4. We couldn't get details of this article at this time:
   10.1101/2023.05.15.540723

5. We couldn't get details of this article at this time:
   10.1101/2023.04.03.535429

6. Mechanical coupling coordinates microtubule growth

   This article has 6 authors:

   1. Bonnibelle K Leeds
   2. Katelyn F Kostello
   3. Yuna Y Liu
   4. Christian R Nelson
   5. Sue Biggins
   6. Charles L Asbury

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     In this technically advanced and important piece of work, the authors study the coordination of microtubule growth in kinetochore fibers using force spectroscopy and numerical simulations. With compelling evidence the authors address the question of how microtubules, which naturally exhibit variable growth rates, can coordinate their behavior by mechanical coupling so as to function as a single unit in generating forces during chromosome segregation.

   Reviewed by eLife

7. We couldn't get details of this article at this time:
   10.1101/2022.12.07.519534

8. We couldn't get details of this article at this time:
   10.1101/2023.06.25.546468

9. Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays

   This article has 13 authors:

   1. Xueyang Pan
   2. Albert N Alvarez
   3. Mengqi Ma
   4. Shenzhao Lu
   5. Michael W Crawford
   6. Lauren C Briere
   7. Oguz Kanca
   8. Shinya Yamamoto
   9. David A Sweetser
   10. Jenny L Wilson
   11. Ruth J Napier
   12. Jonathan N Pruneda
   13. Hugo J Bellen

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     The authors establish a Drosophila model to assess the severity of disease-linked alleles of Uba5. Using both in vivo and in vitro experiments, this valuable study demonstrates the alleles fall into mild, intermediate, and severe classes, with convincing evidence to support their conclusion. This well-executed study establishes a model for further characterization of Uba5-related phenotypes in a powerful model system.

   Reviewed by eLife

10. Multiomics analyses reveal dynamic bioenergetic pathways and functional remodeling of the heart during intermittent fasting

    This article has 26 authors:

    1. Thiruma V Arumugam
    2. Asfa Alli-Shaik
    3. Elisa A Liehn
    4. Sharmelee Selvaraji
    5. Luting Poh
    6. Vismitha Rajeev
    7. Yoonsuk Cho
    8. Yongeun Cho
    9. Jongho Kim
    10. Joonki Kim
    11. Hannah LF Swa
    12. David Tan Zhi Hao
    13. Chutima Rattanasopa
    14. David Yang-Wei Fann
    15. David Castano Mayan
    16. Gavin Yong-Quan Ng
    17. Sang-Ha Baik
    18. Karthik Mallilankaraman
    19. Mathias Gelderblom
    20. Grant R Drummond
    21. Christopher G Sobey
    22. Brian K Kennedy
    23. Roshni R Singaraja
    24. Mark P Mattson
    25. Dong-Gyu Jo
    26. Jayantha Gunaratne

    This article has been curated by 1 group:

    • Curated by eLife

      eLife assessment

      This study provides a useful catalog of the cardiac proteome and transcriptome in response to intermittent fasting. Although mechanistic integration is limited, the technical aspects have been executed in a solid way, and sufficient evidence is provided to support the main conclusions. Future work can build on this study to expand our understanding of the relationship between dietary perturbations and cardiac function.

    Reviewed by eLife