Latest preprint reviews

  1. Suggestion of creatine as a new neurotransmitter by approaches ranging from chemical analysis and biochemistry to electrophysiology

    This article has 8 authors:
    1. Xiling Bian
    2. Jiemin Zhu
    3. Xiaobo Jia
    4. Wenjun Liang
    5. Sihan Yu
    6. Zhiqiang Li
    7. Wenxia Zhang
    8. Yi Rao
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This study presents valuable observations on a potential role of creatine (Cr) as a novel neurotransmitter. While the data provide compelling evidence that Cr is present in synaptic vesicles, the evidence that Cr is synaptically released and binds to a post-synaptic receptor is incomplete, as no receptor is described. With further evidence, these results will be of wide interest to the field of neuroscience.

    Reviewed by eLife

    This article has 18 evaluationsAppears in 1 listLatest version Latest activity
  2. Rapid cloning-free mutagenesis of new SARS-CoV-2 variants using a novel reverse genetics platform

    This article has 10 authors:
    1. Enja Tatjana Kipfer
    2. David Hauser
    3. Martin J Lett
    4. Fabian Otte
    5. Lorena Urda
    6. Yuepeng Zhang
    7. Christopher MR Lang
    8. Mohamed Chami
    9. Christian Mittelholzer
    10. Thomas Klimkait
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This study describes CLEVER, an improved method for fast and efficient rescue and mutagenesis of SARS-CoV2. While the principle of this method is not new, this work significantly improves upon existing protocols, providing an important advancement in the field of viral infectious clones. Convincing proof-of-concept experiments were performed that demonstrate the utility and efficiency of the method.

    Reviewed by eLife

    This article has 6 evaluationsAppears in 1 listLatest version Latest activity
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