Latest preprint reviews

  1. Brain-imaging evidence for compression of binary sound sequences in human memory

    This article has 4 authors:
    1. Fosca Al Roumi
    2. Samuel Planton
    3. Liping Wang
    4. Stanislas Dehaene
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This article brings to bear a useful, extensive set of behavioral methods and neural data to report that activity in numerous cortical regions robustly covaries with the complexity of tone sequences encoded in memory. In its current state, the findings are solid but deserve further analysis to arrive at more convincing conclusions.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  2. Discovery and biological evaluation of a potent small molecule CRM1 inhibitor for its selective ablation of extranodal NK/T cell lymphoma

    This article has 11 authors:
    1. He Liu
    2. Meisuo Liu
    3. Xibao Tian
    4. Haina Wang
    5. Jiujiao Gao
    6. Hanrui Li
    7. Zhehuan Zhao
    8. Yu Liu
    9. Caigang Liu
    10. Xuan Chen
    11. Yongliang Yang
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This study reports a valuable finding on the discovery and evaluation of a potent small molecule inhibitor for CRM1 that may be important to treat extranodal NK/T cell lympohma (ENKTL). The evidence supporting the claims of the authors is solid that reflects an important finding for novel CRM1 inhibitors to treat ENKTL, although additional experimental evidence is needed. The work will be of interest to cancer biologists working on ENKTL.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  3. Cystatin F (Cst7) drives sex-dependent changes in microglia in an amyloid-driven model of Alzheimer’s disease

    This article has 15 authors:
    1. Michael JD Daniels
    2. Lucas Lefevre
    3. Stefan Szymkowiak
    4. Alice Drake
    5. Laura McCulloch
    6. Makis Tzioras
    7. Jack Barrington
    8. Owen R Dando
    9. Xin He
    10. Mehreen Mohammad
    11. Hiroki Sasaguri
    12. Takashi Saito
    13. Takaomi C Saido
    14. Tara L Spires-Jones
    15. Barry W McColl
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This study presents a valuable finding on the function of the gene Cst7 in sex-divergent pathological changes in microglia in a mouse model of AB-driven Alzheimer's disease. The evidence supporting the claims of the authors is solid, although the study would be strengthened by validation of some of the key differentially expressed genes identified in RNA-sequencing experiments, and the inclusion of key controls and additional timepoints to address whether Cst7 drives disease progression or is simply upregulated as a result. The work will be of interest to neuroimmunologists and neuroscientists working on microglia and neurodegenerative disease.

    Reviewed by eLife

    This article has 5 evaluationsAppears in 1 listLatest version Latest activity
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