Latest preprint reviews

  1. Ice nucleation proteins self-assemble into large fibres to trigger freezing at near 0 °C

    This article has 10 authors:
    1. Thomas Hansen
    2. Jocelyn Lee
    3. Naama Reicher
    4. Gil Ovadia
    5. Shuaiqi Guo
    6. Wangbiao Guo
    7. Jun Liu
    8. Ido Braslavsky
    9. Yinon Rudich
    10. Peter L Davies
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This valuable study provides molecular-level insights into the functional mechanism of bacterial ice-nucleating proteins, detailing electrostatic interactions in the domain architecture of multimeric assemblies. The evidence supporting the claims of the authors is solid, with results from protein engineering experiments, functional assays, and cryo-electron tomography, while the proposed structural model of protein self-assembly remains hypothetical. The work is of broad interest to researchers in the fields of protein structural biology, biochemistry, and biophysics, with implications in microbial ecology and atmospheric glaciation.

    Reviewed by eLife

    This article has 9 evaluationsAppears in 1 listLatest version Latest activity
  2. Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications

    This article has 19 authors:
    1. Riham Ayoubi
    2. Joel Ryan
    3. Michael S Biddle
    4. Walaa Alshafie
    5. Maryam Fotouhi
    6. Sara Gonzalez Bolivar
    7. Vera Ruiz Moleon
    8. Peter Eckmann
    9. Donovan Worrall
    10. Ian McDowell
    11. Kathleen Southern
    12. Wolfgang Reintsch
    13. Thomas M Durcan
    14. Claire Brown
    15. Anita Bandrowski
    16. Harvinder Virk
    17. Aled M Edwards
    18. Peter McPherson
    19. Carl Laflamme
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      Antibodies are some of the most critical tools in biomedical research. However, their quality and specificity vary significantly. This fundamental study provides guidelines for how the quality of an antibody should be assessed and recorded and provides compelling data on the selected antibodies. This paper will be of interest to researchers working in experimental cell biology.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
Newer Page 423 of 871 Older