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  1. BMP signalling facilitates transit amplification in the developing chick and human cerebellum

    This article has 5 authors:
    1. Victoria Rook
    2. Parthiv Haldipur
    3. Kathleen J Millen
    4. Thomas Butts
    5. Richard J Wingate
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This study investigates BMP signaling mechanisms in the developing chick cerebellum to better understand germinal layer formation, cellular amplification and neuronal differentiation. The data from human tissue is compelling and lends support to the possible links of these processes to medulloblastoma, although this study does raise exciting questions regarding the generalized role of BMP signaling during normal development and malignant growth. Overall, this is an important study with beautifully presented findings.

    Reviewed by eLife

    This article has 7 evaluationsAppears in 1 listLatest version Latest activity
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