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  1. Comparative analysis of multiplexed in situ gene expression profiling technologies

    This article has 2 authors:
    1. Austin Hartman
    2. Rahul Satija
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      Hartman et al.'s important research examines six commonly utilized imaging-based multiplexed transcriptomic techniques and introduces a novel specificity metric, "MECR," to streamline platform evaluations. The authors highlight the crucial influence of cell segmentation methodologies on outcomes, offering insight into the field. Nonetheless, the substantiation for the principal assertions remains incomplete, as the comparisons across platforms seem uneven due to variations in gene panels.

    Reviewed by eLife

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