eLife

Latest preprint reviews

1. We couldn't get details of this article at this time:
   10.1101/2024.02.18.580792

2. We couldn't get details of this article at this time:
   10.1101/2024.06.18.599556

3. Endogenous FGFs drive ERK-dependent cell fate patterning in 2D human gastruloids

   This article has 9 authors:

   1. Kyoung Jo
   2. Zong-Yuan Liu
   3. Gauri Patel
   4. Zhiyuan Yu
   5. LiAng Yao
   6. Seth Teague
   7. Craig Johnson
   8. Jason Spence
   9. Idse Heemskerk

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This work is an important contribution to understanding the role of FGF signaling in the induction of primitive-like cells in a 2D system of human gastrulation. The authors provide compelling evidence showing that endogenous FGF ligands, acting through FGF receptors localized basolaterally, are determinant in the acquisition of specific cell fates. These observations will be of broad relevance to the FGF field.

   Reviewed by eLife

4. A multiscale model of striatum microcircuit dynamics

   This article has 4 authors:

   1. Federico Tesler
   2. Alexander Kozlov
   3. Sten Grillner
   4. Alain Destexhe

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This study is potentially valuable, however currently its findings are incomplete, in that the paper's promise to deliver multiscale models that further our understanding of striatal function remains largely unfulfilled. A major weakness is that the findings are not integrated well within the rich landscape of existing striatal network modeling literature. Another major weakness is that the model is explored only in overly simplified scenarios and with limited comparison to data.

   Reviewed by eLife

5. We couldn't get details of this article at this time:
   10.1101/2023.11.17.567545

6. The title and authors for this article are not available from our external data provider yet:
   10.48550/arxiv.2404.07102v3

7. We couldn't get details of this article at this time:
   10.1101/2024.06.13.598779

8. Kynurenine monooxygenase blockade reduces endometriosis-like lesions, improves visceral hyperalgesia, and rescues mice from a negative behavioural phenotype in experimental endometriosis

   This article has 22 authors:

   1. Ben Higgins
   2. Ioannis Simitsidellis
   3. Xiaozhong Zheng
   4. Frances Collins
   5. Natalie ZM Homer
   6. Scott G Denham
   7. Joanna P Simpson
   8. Mike Millar
   9. Lyndsey Boswell
   10. Hee Y Lee
   11. Yeon G Kim
   12. Kyung H Park
   13. Larry C Park
   14. Patrick J Sweeney
   15. Gerard Feraille
   16. Alessandro Taddei
   17. David Chagras
   18. Thierry Alvarez
   19. Scott P Webster
   20. Andrew Horne
   21. Philippa TK Saunders
   22. Damian J Mole

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This useful study holds importance within the focused scope of endometriosis treatment, providing initial evidence of a potential new therapeutic target. The strength of the evidence is solid, as the methods, data, and analyses support the authors' conclusions regarding the specific aims. The study provides promising preliminary evidence of KMO implication in endometriosis, but it falls short of establishing a strong rationale for proposing KNS898 as a treatment for endometriosis given the limitations in evidence and mechanistic insights.

   Reviewed by eLife

9. We couldn't get details of this article at this time:
   10.1101/2024.05.13.593697

10. We couldn't get details of this article at this time:
    10.1101/2024.05.03.589936