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  1. The glycoprotein quality control factor Malectin promotes coronavirus replication and viral protein biogenesis

    This article has 2 authors:
    1. Jonathan P Davies
    2. Lars Plate
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This is an important study that utilizes proteomic and genetic approaches to identify the glycoprotein quality control factor malectin as a pro-viral host protein involved in the replication of coronavirus. The evidence supporting this conclusion is convincing, although continued elucidation of the mechanistic basis of malectin-mediated viral replication would further strengthen these findings. This work will be of interest to cell biologists studying the molecular mechanisms of glycoprotein quality control and virologists studying the host-pathogen interactions.

    Reviewed by eLife

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