Latest preprint reviews

  1. Different treatment durations of loperamide in preventing pyrotinib-induced diarrhea: A randomized, parallel-group sub-study of the phase II PHAEDRA trial

    This article has 22 authors:
    1. Changjun Wang
    2. Yan Lin
    3. Ying Xu
    4. Feng Mao
    5. Jinghong Guan
    6. Xuejing Wang
    7. Yanna Zhang
    8. Xiaohui Zhang
    9. Songjie Shen
    10. Ying Zhong
    11. Bo Pan
    12. Li Peng
    13. Xin Huang
    14. Xi Cao
    15. Ru Yao
    16. Xintong Zhou
    17. Zecheng He
    18. Yuhan Liu
    19. Jie Lang
    20. Chenggang Li
    21. Yidong Zhou
    22. Qiang Sun
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This study presents a useful finding for the prevention of diarrhea with loperamide in patients with early HER2-positive breast cancer treated with nab-paclitaxel in combination with pyrotinib. The evidence supporting the claims of the authors is somewhat incomplete. The enrollment of patients as a control group who have not received prophylactic treatment for diarrhea would have strengthened the study, and the addition of double-blinding for the assessment of treatment may be necessary. The work will be of interest to scientists working in the field of clinical breast cancer treatment.

    Reviewed by eLife

    This article has 3 evaluationsAppears in 1 listLatest version Latest activity
  2. The inevitability and superfluousness of cell types in spatial cognition

    This article has 3 authors:
    1. Xiaoliang Luo
    2. Robert M Mok
    3. Bradley C Love
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This important study demonstrates that some degree of spatial tuning (e.g., place cells) and ability to decode spatial location emerges in sufficiently complex systems trained to process visual information. This intriguing observation challenges existing approaches and findings used in the study of spatial navigation. However, the strength of evidence regarding the nature and quality of spatial tuning, its compatibility with experimental data, and the overall interpretation of the study remains incomplete. This work will be of interest to the research community of spatial navigation.

    Reviewed by eLife

    This article has 9 evaluationsAppears in 1 listLatest version Latest activity
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