Latest preprint reviews

  1. Multiomics reveals gut dysbiosis contributes to fatty acid dysmetabolism in early phase of acute myocardial infarction

    This article has 30 authors:
    1. Yong Fan
    2. Jiajun Ying
    3. Ning Huangfu
    4. Kewan He
    5. Teng Hu
    6. Pengpeng Su
    7. Xintao Hu
    8. Hequn He
    9. Wei Liang
    10. Junsong Liu
    11. Jinsong Cheng
    12. Shiqi Wang
    13. Ruochi Zhao
    14. Hengyi Mao
    15. Fuwei He
    16. Jia Su
    17. Honglin Zhou
    18. Zhenwei Li
    19. Xiaohong Fei
    20. Xiafei Sun
    21. Peipei Wang
    22. Minfang Guan
    23. Weiping Du
    24. Shaoyi Lin
    25. Yong Wang
    26. Fangkun Yang
    27. Renyuan Fang
    28. Ziqing Kong
    29. Xiaomin Chen
    30. Hanbin Cui
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This study provides valuable information about the microbiome and metabolome, and their correlation with acute myocardial infarction. However, the relationship established between these variables is limited to a correlation, and therefore the strength of the evidence is incomplete.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  2. Apoptotic caspases cleave DRP1 to promote mitochondrial fusion and anti-viral immune responses

    This article has 6 authors:
    1. Yujie Fang
    2. Zihan Guan
    3. Xiangtao Zhu
    4. Zhenqiong Guan
    5. Shufen Li
    6. Ke Peng
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This manuscript describes an unexpected role of cellular caspases in cleaving Drp1, a protein involved in mitochondrial fission, in virus-infected cells. Drp1 cleavage augments mitochondrial fission, reinforcing MAVS-dependent type-1 IFN response against multiple viruses. The findings presented in this manuscript are important and the strength of evidence is solid. Additional studies may allow for more robust mechanistic substantiation of the proposed model.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  3. Structural epitope profiling identifies antibodies associated with critical COVID-19 and long COVID

    This article has 37 authors:
    1. Patrick KA Kearns
    2. Charles Dixon
    3. Mihaly Badonyi
    4. Kim Lee
    5. Rafal Czapiewski
    6. Olivia Fleming
    7. Prajitha Nadukkandy
    8. Lukas Gerasimivicius
    9. Rinal Sahputra
    10. Bethany Potts
    11. Sam Benton
    12. Jacky Guy
    13. Scott Neilson
    14. Helen Wise
    15. Sara Jenks
    16. Kate Templeton
    17. CIRCO
    18. Christina Dold
    19. Teresa Lambe
    20. Andrew Pollard
    21. Alexander J Mentzer
    22. Julian C Knight
    23. COMBAT
    24. Susanna Dunachie
    25. Paul Klenerman
    26. Eleanor Barnes
    27. Alan Carson
    28. Laura McWhirter
    29. Tracy Hussell
    30. Rennos Fragkoudis
    31. Susan Rosser
    32. David Cavanagh
    33. Graeme Cowan
    34. Madhvi Menon
    35. Joseph A Marsh
    36. Dirk A Kleinjan
    37. Nick Gilbert
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This study provides novel insights into COVID-19 immune responses by using the delta of the normalised accessible surface area (DASA) to map IgM responses to the SARS-CoV-2 Membrane protein M1-subtype across multiple European cohorts. The evidence supporting the findings is solid, with thorough validation and comprehensive analysis, although additional clarity on T-independent B cell reactions and the impact of comorbidities would further strengthen the conclusions. The methods and data presented are valuable for advancing diagnostic and prognostic tools for COVID-19, particularly in the context of long COVID.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
Newer Page 247 of 869 Older