eLife

Latest preprint reviews

1. The asymmetric transfers of visual perceptual learning determined by the stability of geometrical invariants

   This article has 5 authors:

   1. Yan Yang
   2. Yan Zhuo
   3. Zhentao Zuo
   4. Tiangang Zhuo
   5. Lin Chen

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This important and unique study proposes a framework to understand and predict generalization in visual perceptual learning in humans based on form invariants. Using behavioral experiments in humans and by training deep networks, the authors offer evidence that the presence of stable invariants in a task leads to faster learning. However, this interpretation is promising but counter-intuitive and incomplete, since there could be possible other confounds such as differing attentional demands that lead to differing patterns of generalization. It can be strengthened through additional experiments and by rejecting alternate explanations.

   Reviewed by eLife

2. Volumetric trans-scale imaging of massive quantity of heterogeneous cell populations in centimeter-wide tissue and embryo

   This article has 12 authors:

   1. Taro Ichimura
   2. Taishi Kakizuka
   3. Yoshitsugu Taniguchi
   4. Satoshi Ejima
   5. Yuki Sato
   6. Keiko Itano
   7. Kaoru Seiriki
   8. Hitoshi Hashimoto
   9. Ko Sugawara
   10. Hiroya Itoga
   11. Shuichi Onami
   12. Takeharu Nagai

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     The important study established a large-scale objective and integrated multiple optical microscopy systems to demonstrate their potential for long-term imaging of the developmental process. The convincing imaging data cover a wide range of biological applications, such as organoids, mouse brains, and quail embryos, but enhancing image quality can further enhance the method's effectiveness. This work will appeal to biologists and imaging technologists focused on long-term imaging of large fields.

   Reviewed by eLife

3. Taste triggers a homeostatic temperature control in hungry flies

   This article has 8 authors:

   1. Yujiro Umezaki
   2. Sergio Hidalgo
   3. Erika Nguyen
   4. Tiffany Nguyen
   5. Jay Suh
   6. Sheena S Uchino
   7. Joanna Chiu
   8. Fumika Hamada

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This paper presents valuable findings that gustation and nutrition might independently influence the preferred environmental temperature in flies. The evidence supporting the main claims is solid and well presented. The finding that flies might thus exhibit a cephalic phase response similar to mammals will be of value for future investigations.

   Reviewed by eLife

4. Linking root-associated fungal and bacterial functions to root economics

   This article has 13 authors:

   1. Ran Wu
   2. Xiaoyue Zeng
   3. M. Luke McCormack
   4. Christopher W. Fernandez
   5. Yin Yang
   6. Hui Guo
   7. Meijie Xi
   8. Yu Liu
   9. Xiangbin Qi
   10. Shuang Liang
   11. Thomas E. Juenger
   12. Roger T. Koide
   13. Weile Chen

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This valuable study advances our understanding of the below-ground resource acquisition strategies of diverse tree species, integrating the roles of both roots and their associated microbes. The support for the conclusions is incomplete owing to the uncertainties or shortcomings associated with the design and statistical analyses. Regardless of these technical issues, this study can be of broad interest for plant and microbial ecologists.

   Reviewed by eLife

5. A myristoyl switch at the plasma membrane triggers cleavage and oligomerization of Mason-Pfizer monkey virus matrix protein

   This article has 8 authors:

   1. Markéta Častorálová
   2. Jakub Sýs
   3. Jan Prchal
   4. Anna Pavlů
   5. Lucie Prokopová
   6. Zina Briki
   7. Martin Hubálek
   8. Tomas Ruml

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This valuable study advances our understanding of how the viral protease in a D-type retrovirus is activated and in particular how the exposure of the myristoyl group is required for processing of the Gag matrix precursor. The supporting evidence is convincing, but the work would benefit from additional data in support of the claims. This manuscript is of interest to retrovirologists and structural biologists.

   Reviewed by eLife

6. Ingestible pills reveal gastric correlates of emotions

   This article has 4 authors:

   1. Giuseppina Porciello
   2. Alessandro Monti
   3. Maria Serena Panasiti
   4. Salvatore Maria Aglioti

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This important study used a novel method to relate gastric acidity to subjective ratings of emotions induced by video clips. The findings are solid but could be strengthened by additional analyses and/or visualization. The findings have broad implications for the field of emotion research and opens new avenues of research for understanding psychosomatic disorders.

   Reviewed by eLife

7. Disruption of awake sharp-wave ripples does not affect memorization of locations in repeated-acquisition spatial memory tasks

   This article has 2 authors:

   1. Lies Deceuninck
   2. Fabian Kloosterman

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This manuscript presents the lack of effect of closed-loop SWR disruption in guiding behavior and remembering the recent past in short-term memory tasks in rats. These negative results may have important theoretical and practical implications in the field of memory and learning. However, while SWR detection methods are carefully validated, the strength of evidence is incomplete and some additional controls are required.

   Reviewed by eLife

8. Experience transforms crossmodal object representations in the anterior temporal lobes

   This article has 7 authors:

   1. Aedan Yue Li
   2. Natalia Ladyka-Wojcik
   3. Heba Qazilbash
   4. Ali Golestani
   5. Dirk B Walther
   6. Chris B Martin
   7. Morgan D Barense

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     The fMRI study is important because it investigates fundamental questions about the neural basis of multimodal binding using an innovative multi-day learning approach. The results provide solid evidence for learning-related changes in the anterior temporal lobe, however, the interpretation of these changes is not straightforward, and the study does not (yet) provide direct evidence for an integrative code. This paper is of potential interest to a broad audience of neuroscientists.

   Reviewed by eLife

9. The interferon-rich skin environment regulates Langerhans cell ADAM17 to promote photosensitivity in lupus

   This article has 25 authors:

   1. Thomas Morgan Li
   2. Victoria Zyulina
   3. Ethan S Seltzer
   4. Marija Dacic
   5. Yurii Chinenov
   6. Andrea R Daamen
   7. Keila R Veiga
   8. Noa Schwartz
   9. David J Oliver
   10. Pamela Cabahug-Zuckerman
   11. Jose Lora
   12. Yong Liu
   13. William D Shipman
   14. William G Ambler
   15. Sarah F Taber
   16. Karen B Onel
   17. Jonathan H Zippin
   18. Mehdi Rashighi
   19. James G Krueger
   20. Niroshana Anandasabapathy
   21. Inez Rogatsky
   22. Ali Jabbari
   23. Carl P Blobel
   24. Peter E Lipsky
   25. Theresa T Lu

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This study presents a useful assessment of the possible role of type I interferons in inhibiting Adam17 protease/sheddase activity and their correlation with decreased Langerhans Cells signature in lesional and nonlesional CLE and murine models as cause of photosensitive lupus. The data were collected and analyzed using a solid methodology. This work will be of interest to scientists interested in photosensitivity in the setting of lupus.

   Reviewed by eLife

10. Coenzyme-Protein Interactions since Early Life

    This article has 5 authors:

    1. Alma Carolina Sanchez-Rocha
    2. Mikhail Makarov
    3. Lukáš Pravda
    4. Marian Novotný
    5. Klára Hlouchová

    This article has been curated by 1 group:

    • Curated by eLife

      eLife Assessment

      This study presents a valuable examination of the prevalence of interactions between amino acids from different periods of Earth's history and coenzymes. While the premise of this work is well founded and the analysis is solid, with more data, the interpretation could change. This manuscript would be of interest to evolutionary biologists and biophysicists.

    Reviewed by eLife