Latest preprint reviews

  1. Parvalbumin interneuron ErbB4 controls ongoing network oscillations and olfactory behaviors in mice

    This article has 7 authors:
    1. Bin Hu
    2. Chi Geng
    3. Feng Guo
    4. Ying Liu
    5. Ran Wang
    6. You-Ting Chen
    7. Xiao-Yu Hou
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This study provides useful information on the potential role of ERbB4 expression in parvalbumin-positive cells on olfactory behaviour and circuit dynamics in the olfactory bulb. The question is timely and novel, and findings could shed light on the critical role that ErbB4 may play in modulating olfactory bulb cell function and olfactory perception. Although the authors use a comprehensive set of experiments for their analysis, the evidence is incomplete as many of the experiments are underpowered and the model for selective knockout of ErbB4 in olfactory parvalbumin cells is not validated.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  2. MED26-enriched condensates drive erythropoiesis through modulating transcription pausing

    This article has 20 authors:
    1. Shicong Zhu
    2. Xiaoting Zhang
    3. Na Li
    4. Xinying Zhao
    5. Man Li
    6. Si Xie
    7. Qiuyu Yue
    8. Yunfeng Li
    9. Dong Li
    10. Fan Wu
    11. Zile Zhang
    12. Ziqi Feng
    13. Yiyang Zhang
    14. Wonhyung Choi
    15. Xinyi Jia
    16. Yuelin Deng
    17. Qi Hu
    18. Xingyun Yao
    19. Xiaofei Gao
    20. Hsiang-Ying Lee
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      The study is important to show the role of MED26 in red cell formation. Linking transcription pausing with erythropoiesis is a key discovery. The data are solid although there are still spaces to improve. The in vivo data are limited by specificity concerns on their Cre model. Having RNA-seq, using more erythroid markers such as band3 and a4-integrin, and orthogonal validation with iPSC-erythropoiesis model will improve the study.

    Reviewed by eLife

    This article has 5 evaluationsAppears in 1 listLatest version Latest activity
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