Latest preprint reviews

  1. Mechanical imbalance between normal and transformed cells drives epithelial homeostasis through cell competition

    This article has 9 authors:
    1. Praver Gupta
    2. Sayantani Kayal
    3. Nobuyuki Tanimura
    4. Shilpa P Pothapragada
    5. Harish K Senapati
    6. Padmashree Devendran
    7. Yasuyuki Fujita
    8. Dapeng Bi
    9. Tamal Das
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      In this important study, the authors combine innovative experimental approaches, including direct compressibility measurements and traction force analyses, with theoretical modeling to propose that wild-type cells exert compressive forces on softer HRasV12-transformed cells, influencing competition outcomes. The data generally provide solid evidence that transformed epithelial cells exhibit higher compressibility than wild-type cells, a property linked to their compaction during mechanical cell competition. However, the study would benefit from further characterization of how compression affects the behavior of HRasV12 cells and clearer causal links between compressibility and competition outcomes.

    Reviewed by eLife

    This article has 7 evaluationsAppears in 1 listLatest version Latest activity
  2. Neural adaptation to the eye’s optics through phase compensation

    This article has 4 authors:
    1. Antoine Barbot
    2. John T Pirog
    3. Cherlyn J Ng
    4. Geunyoung Yoon
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This paper shows convincingly that the human visual system can recalibrate itself to compensate for phase alterations in an image induced by optical blur. This phenomenon is studied using state-of-the-art adaptive optics approaches that allow the manipulation of the eye's optics while making concurrent psychophysical measurements. The findings are broadly important because they highlight a neural mechanism by which flawed information is used to create seemingly accurate perceptions of the visual environment.

    Reviewed by eLife

    This article has 3 evaluationsAppears in 1 listLatest version Latest activity
Newer Page 188 of 868 Older