eLife

Latest preprint reviews

1. We couldn't get details of this article at this time:
   10.1101/2024.08.22.609218

2. We couldn't get details of this article at this time:
   10.1101/2024.07.02.601674

3. We couldn't get details of this article at this time:
   10.1101/2023.06.26.546519

4. We couldn't get details of this article at this time:
   10.1101/2024.07.17.602099

5. We couldn't get details of this article at this time:
   10.1101/2024.07.26.605364

6. We couldn't get details of this article at this time:
   10.1101/2024.11.13.623404

7. We couldn't get details of this article at this time:
   10.1101/2024.11.05.622032

8. Reconstruction of functional olfactory sensory tissue from embryonic nasal stem cells

   This article has 3 authors:

   1. Kazuya Suzuki
   2. Fumi Wagai
   3. Mototsugu Eiraku

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This manuscript presents a valuable study utilizing an in vitro organoid system to recapitulate the developmental process of the olfactory epithelium. The authors provided solid evidence indicating that a combination of niche factors can induce organoid development and give rise to multiple cell types. However, the calcium imaging part of the study could be seen as a limitation.

   Reviewed by eLife

9. p53 engagement is a hallmark of an unfolded protein response in the nucleus of mammalian cells

   This article has 2 authors:

   1. Joseph H Park
   2. Thomas J Wandless

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This paper presents useful findings that misfolded proteins in the nucleus can impair proteasomal degradation and activate p53. The results supporting the findings are largely solid, but incomplete. The manuscript could be strengthened by including more quantitative data analyses and additional experimentation/discussions on the mechanism of p53 activation by misfolded nuclear proteins. The work will be interesting primarily to scientists studying protein homeostasis.

   Reviewed by eLife

10. We couldn't get details of this article at this time:
    10.1101/2024.09.03.24312808