Latest preprint reviews

  1. SICKO: Systematic Imaging of Caenorhabditis Killing Organisms

    This article has 12 authors:
    1. Luis S Espejo
    2. Samuel Freitas
    3. Vanessa Hofschneider
    4. Leah Chang
    5. Angelo Antenor
    6. Jonah Balsa
    7. Anne Haskins
    8. Destiny DeNicola
    9. Hope Dang
    10. Sage Hamming
    11. Delaney Kelser
    12. George L Sutphin
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This work describes a valuable method, SICKO, for real-time longitudinal quantification of bacterial colonization in the gut of individual C. elegans. The authors present convincing evidence to support the validity of the approach. SICKO provides an experimental framework that will enable progress in our understanding of host-microbe interactions.

    Reviewed by eLife

    This article has 3 evaluationsAppears in 1 listLatest version Latest activity
  2. DDX3 Regulates the Cap‐Independent Translation of the Japanese Encephalitis Virus via Its Interactions with PABP1 and the Untranslated Regions of the Viral Genome

    This article has 14 authors:
    1. Chenxi Li
    2. Linjie Zhang
    3. Chenyang Tang
    4. Xuan Chen
    5. Jing Shi
    6. Qingyu Li
    7. Xue Jiao
    8. Jinyao Guo
    9. Bin Wang
    10. Kefan Bu
    11. Abdul Wahaab
    12. Yuguo Yuan
    13. Ming‐an Sun
    14. Yanhua Li
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This work is a valuable study that presents a detailed analysis of translation, driven by the untranslated regions of the Japanese encephalitis virus. It reports a role for the RNA helicase DDX3 in promoting a cap-independent translation mechanism. The conclusions are based on generally solid evidence, although there are some weaknesses in the overall model based on suboptimal experimental approaches and over-interpretation of some of the data. Addressing deficiencies noted in peer review could elevate the impact of the study.

    Reviewed by eLife

    This article has 5 evaluationsAppears in 1 listLatest version Latest activity
  3. Screening Envelope Genes Across Primate Genomes Reveals Evolution and Diversity Patterns of Endogenous Retroviruses

    This article has 5 authors:
    1. Saili Chabukswar
    2. Nicole Grandi
    3. Elena Soddu
    4. Liang-Tzung Lin
    5. Enzo Tramontano
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      The manuscript provides an important assessment of the number and distribution of different retrovirus env genes present in primate genomes in the form of ancient endogenous retroviruses (ERV loci) and the potential role that viral recombination played in the diversification of retrovirus env genes and their propagation in the primate germline over millions of years. The paper convincingly describes how intermixing/recombination occurs with this viruses, representing a conceptual advance with potentially broad implications.

    Reviewed by eLife

    This article has 7 evaluationsAppears in 1 listLatest version Latest activity
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