Latest preprint reviews

  1. Selective loss of Nkx2.1 -lineage neurons in the lateral septum alters the balance between novelty seeking and threat avoidance

    This article has 12 authors:
    1. Miguel Turrero García
    2. Diana N. Tran
    3. Ralph E. Peterson
    4. Leena A. Ibrahim
    5. Christopher M. Reid
    6. Sarah M. Hanson
    7. Yuqi Ren
    8. Fiona Dale-Huang
    9. Yajun Xie
    10. Sarah K. Stegmann
    11. Steve Vu
    12. Corey C. Harwell
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This important study integrates mouse genetics with sequencing, electrophysiological and behavioral tools to uncover the behavioral role and molecular profile of a developmentally defined subpopulation in the lateral septum. The data collected and analyzed are convincing, highlighting the role of this subpopulation in threat avoidance and stress, providing a framework by which developmental origin is linked to mature neuronal function. The work will be of interest to biologists and neuroscientists working on development and behavior.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  2. Topological structure in human spatial representation revealed through drawing

    This article has 4 authors:
    1. Mahwish Kittur
    2. Agnes Zhang
    3. Nessa V. Bryce
    4. Sami R. Yousif
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This important paper provides evidence that visual representations, as observed through drawing, preferentially preserve topological features over metric features. Across three experiments with different age groups and creative converging methods, they demonstrate that holes and T-junctions are relatively preserved as compared to topologically irrelevant L-junctions, and Euclidian features like length or precise angle. Together, these data provide convincing evidence for topology as an organizing principle for spatial representation, but the work would be strengthened by considering a broader range of topological features, or by ruling out alternative accounts, like preserved memory for complex features, motor production limitations, or noisy compression, that may produce a similar pattern without a topological prior.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
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