Neuroscience

Population encoding of stimulus features along the visual hierarchy

1. Luciano Dyballa
2. Andra M. Rudzite
3. Mahmood S. Hoseini
4. Mishek Thapa
5. Michael P. Stryker
6. Greg D. Field
7. Steven W. Zucker

Reviewed by PREreview

Molecular consequences of peripheral Influenza A infection on cell populations in the murine hypothalamus

1. René Lemcke
2. Christine Egebjerg
3. Nicolai T Berendtsen
4. Kristoffer L Egerod
5. Allan R Thomsen
6. Tune H Pers
7. Jan P Christensen
8. Birgitte R Kornum

• Curated by eLife

  eLife assessment

  This important study combines experiments and computational approaches to understand the effects of influenza H1N1 infection on hypothalamic cells. The methodology and analysis are solid and raise questions around how a respiratory virus affects the central nervous system.

Reviewed by eLife

Glial Draper signaling triggers cross-neuron plasticity in bystander neurons after neuronal cell death

1. Yupu Wang
2. Ruiling Zhang
3. Sihao Huang
4. Parisa Tajalli-Tehrani Valverde
5. Meike Lobb-Rabe
6. James Ashley
7. Lalanti Venkatasubramanian
8. Robert A. Carrillo

Reviewed by preLights

Microglia Regulate Sleep via Calcium-Dependent Modulation of Norepinephrine Transmission

1. Chenyan Ma
2. Bing Li
3. Daniel Silverman
4. Xinlu Ding
5. Anan Li
6. Chi Xiao
7. Ganghua Huang
8. Kurtresha Worden
9. Sandra Muroy
10. Wei Chen
11. Zhengchao Xu
12. Chak Foon Tso
13. Yixuan Huang
14. Yufan Zhang
15. Qingming Luo
16. Kaoru Saijo
17. Yang Dan

Reviewed by Arcadia Science

Dynamic corticothalamic modulation of the somatosensory thalamocortical circuit during wakefulness

1. Elaida D. Dimwamwa
2. Aurélie Pala
3. Vivek Chundru
4. Nathaniel C. Wright
5. Garrett B. Stanley

Reviewed by Arcadia Science

Objective assessment of visual attention in toddlerhood

1. E. Braithwaite
2. V. Kyriakopoulou
3. L. Mason
4. A. Davidson
5. N. Tusor
6. N. Harper
7. M. Earl
8. S. Datoo-Partridge
9. A. Young
10. A. Chew
11. S. Falconer
12. Joseph V Hajnal
13. M.H. Johnson
14. C. Nosarti
15. A.D. Edwards
16. E.J.H. Jones

• Curated by eLife

  eLife assessment

  This study, based on a large-scale data set and established behavioural tasks, has the potential to provide a valuable contribution to the literature if the authors could combine and correlate their behavioural evaluations with neural data and/or clinical assessments. As a standalone dataset, however, the current study appears incomplete because it does not go beyond merely replicating existing findings in a large cohort of children. In order to elevate their study, the authors are encouraged to publish their full dataset and explore the relationship between behavioural and neural or clinical data.

Reviewed by eLife

Atypical cognitive training-induced learning and brain plasticity and their relation to insistence on sameness in children with autism

1. Jin Liu
2. Hyesang Chang
3. Daniel A Abrams
4. Julia Boram Kang
5. Lang Chen
6. Miriam Rosenberg-Lee
7. Vinod Menon

• Curated by eLife

  eLife assessment

  This is an important study on learning strategy differences in autism vs typically developing controls. The study identifies similar learning rates but different learning strategies. The evidence provided by the authors is convincing, relying on well-done tasks and fMRI analyses.

Reviewed by eLife

Reward contingency gates selective cholinergic suppression of amygdala neurons

1. Eyal Y Kimchi
2. Anthony Burgos-Robles
3. Gillian A Matthews
4. Tatenda Chakoma
5. Makenzie Patarino
6. Javier C Weddington
7. Cody Siciliano
8. Wannan Yang
9. Shaun Foutch
10. Renee Simons
11. Ming-fai Fong
12. Miao Jing
13. Yulong Li
14. Daniel B Polley
15. Kay M Tye

• Curated by eLife

  eLife assessment

  This valuable manuscript examines the role of basal forebrain cholinergic (ACh) projection neurons and their inputs to the basolateral amygdala (BLA) and effects on BLA activity during reward seeking. The manuscript provides compelling evidence that ACh may have different effects on network activity in the BLA depending on the state of the network during reward engagement, whereas behavioural data indicating that these ACh neurons/inputs are involved in uncued reward seeking specifically is somewhat less complete. The paper will be of interest to those studying amygdala circuitry, reward processing, and neuromodulation broadly defined.

Reviewed by eLife

Gaze patterns and brain activations in humans and marmosets in the Frith-Happé theory-of-mind animation task

1. Audrey Dureux
2. Alessandro Zanini
3. Janahan Selvanayagam
4. Ravi S Menon
5. Stefan Everling

• Curated by eLife

  eLife assessment

  This study provides useful findings regarding the capacity for mental state attribution on the Frith-Happé task in a highly social non-human primate species, the marmoset. The methods are solid, integrating validated brain imaging and eye-tracking techniques, however, the theoretical analysis is incomplete due to the omission of a "goal-directed condition." The inclusion of the goal-directed condition would enable a stronger interpretation of the findings and would be of broad interest to neuroscientists working in social and affective sciences.

Reviewed by eLife

Neural circuit mechanisms for transforming learned olfactory valences into wind-oriented movement

1. Yoshinori Aso
2. Daichi Yamada
3. Daniel Bushey
4. Karen L Hibbard
5. Megan Sammons
6. Hideo Otsuna
7. Yichun Shuai
8. Toshihide Hige

• Curated by eLife

  eLife assessment

  This study provides important new insights into how learning affects behavior in the Drosophila model. Using a combination of connectomics, neurophysiology, and behavioral analysis, a small group of neurons in the Drosophila brain that integrates learned odor valences and promotes odor tracking by driving upwind orientation and movement is described. The study's conclusion is supported by convincing evidence and rigorous quantitative analysis. Insights from the neural circuit mechanism that translates learning-induced plasticity into appropriate behavioral actions will be of broad interest to neuroscientists.

Reviewed by eLife