Molecular Biology

  1. Thermodynamically coupled biosensors for detecting neutralizing antibodies against SARS-CoV-2 variants

    1. Jason Z. Zhang
    2. Hsien-Wei Yeh
    3. Alexandra C. Walls
    4. Basile I. M. Wicky
    5. Kaitlin R. Sprouse
    6. Laura A. VanBlargan
    7. Rebecca Treger
    8. Alfredo Quijano-Rubio
    9. Minh N. Pham
    10. John C. Kraft
    11. Ian C. Haydon
    12. Wei Yang
    13. Michelle DeWitt
    14. John E. Bowen
    15. Cameron M. Chow
    16. Lauren Carter
    17. Rashmi Ravichandran
    18. Mark H. Wener
    19. Lance Stewart
    20. David Veesler
    21. Michael S. Diamond
    22. Alexander L. Greninger
    23. David M. Koelle
    24. David Baker

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  2. Increased lung cell entry of B.1.617.2 and evasion of antibodies induced by infection and BNT162b2 vaccination

    1. Prerna Arora
    2. Amy Kempf
    3. Inga Nehlmeier
    4. Anzhalika Sidarovich
    5. Nadine Krüger
    6. Luise Graichen
    7. Anna-Sophie Moldenhauer
    8. Martin S. Winkler
    9. Sebastian Schulz
    10. Hans-Martin Jäck
    11. Metodi V. Stankov
    12. Georg M. N. Behrens
    13. Stefan Pöhlmann
    14. Markus Hoffmann

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  3. Influence of viral transport media and freeze-thaw cycling on the sensitivity of qRT-PCR detection of SARS-CoV-2 nucleic acids

    1. Cian Holohan
    2. Sophia Hanarahan
    3. Nathan Feely
    4. Peng Li
    5. John O’Connell
    6. Catherine Moss
    7. Michael Carr
    8. Oya Tagit
    9. Gil U Lee

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. Molecular Dynamics Analysis of Fast-Spreading Severe Acute Respiratory Syndrome Coronavirus 2 Variants and Their Effects on the Interaction with Human Angiotensin-Converting Enzyme 2

    1. Anacleto Silva de Souza
    2. Vitor Martins de Freitas Amorim
    3. Gabriela D. A. Guardia
    4. Felipe R. C. dos Santos
    5. Filipe F. dos Santos
    6. Robson Francisco de Souza
    7. Guilherme de Araujo Juvenal
    8. Yihua Huang
    9. Pingju Ge
    10. Yinan Jiang
    11. Coco Li
    12. Prajwal Paudel
    13. Henning Ulrich
    14. Pedro A. F. Galante
    15. Cristiane Rodrigues Guzzo

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  5. Double-stranded RNA drives SARS-CoV-2 nucleocapsid protein to undergo phase separation at specific temperatures

    1. Christine A Roden
    2. Yifan Dai
    3. Catherine A Giannetti
    4. Ian Seim
    5. Myungwoon Lee
    6. Rachel Sealfon
    7. Grace A McLaughlin
    8. Mark A Boerneke
    9. Christiane Iserman
    10. Samuel A Wey
    11. Joanne L Ekena
    12. Olga G Troyanskaya
    13. Kevin M Weeks
    14. Lingchong You
    15. Ashutosh Chilkoti
    16. Amy S Gladfelter

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. In vitro evaluation of the effect of mutations in primer binding sites on detection of SARS-CoV-2 by RT-qPCR

    1. Fee Zimmermann
    2. Maria Urban
    3. Christian Krüger
    4. Mathias Walter
    5. Roman Wölfel
    6. Katrin Zwirglmaier

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  7. Irradiation of UVC LED at 277 nm inactivates coronaviruses by photodegradation of spike protein

    1. Qunxiang Ong
    2. J. W. Ronnie Teo
    3. Joshua Dela Cruz
    4. Elijah Wee
    5. Winson Wee
    6. Weiping Han

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. MINERVA: A Facile Strategy for SARS-CoV-2 Whole-Genome Deep Sequencing of Clinical Samples

    1. Chen Chen
    2. Jizhou Li
    3. Lin Di
    4. Qiuyu Jing
    5. Pengcheng Du
    6. Chuan Song
    7. Jiarui Li
    8. Qiong Li
    9. Yunlong Cao
    10. X. Sunney Xie
    11. Angela R. Wu
    12. Hui Zeng
    13. Yanyi Huang
    14. Jianbin Wang

    Reviewed by ScreenIT, preLights

    2 evaluationsAppears in 2 listsLatest version Latest activity

  9. A twin UGUA motif directs the balance between gene isoforms through CFIm and the mTORC1 signaling pathway

    1. R Samuel Herron
    2. Alexander K Kunisky
    3. Jessica R Madden
    4. Vivian I Anyaeche
    5. May Z Maung
    6. Hun-Way Hwang

    • Curated by eLife

      eLife assessment

      In this valuable report, the authors explore the connection between mTORC signaling and APA regulated by the CFIm complex. Using a combination of genetic and functional genomics approaches, the study reveals that a twin UGUA motif is a potent cis acting regulation of PAS usage that is recognized by CFIm. Overall, the evidence in general is convincing and supports the conclusions and provides the field with additional mechanistic insight of how signaling connects to APA regulatory machinery.

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity

  10. The short isoform of the host antiviral protein ZAP acts as an inhibitor of SARS-CoV-2 programmed ribosomal frameshifting

    1. Matthias M. Zimmer
    2. Anuja Kibe
    3. Ulfert Rand
    4. Lukas Pekarek
    5. Liqing Ye
    6. Stefan Buck
    7. Redmond P. Smyth
    8. Luka Cicin-Sain
    9. Neva Caliskan

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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