Molecular Biology

  1. Molecular analysis of binding region of an ACE2 as a receptor for SARS-CoV-2 between humans and mammals

    1. Takuma Hayashi
    2. Kaoru Aboko
    3. Masaki Mandan
    4. Nobuo Yaegashi
    5. Ikuo Konishi

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  2. SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation

    1. Katharina Schubert
    2. Evangelos D. Karousis
    3. Ahmad Jomaa
    4. Alain Scaiola
    5. Blanca Echeverria
    6. Lukas-Adrian Gurzeler
    7. Marc Leibundgut
    8. Volker Thiel
    9. Oliver Mühlemann
    10. Nenad Ban

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  3. 6-Thioguanine blocks SARS-CoV-2 replication by inhibition of PLpro

    1. Caleb D. Swaim
    2. Varun Dwivedi
    3. Yi-Chieh Perng
    4. Xu Zhao
    5. Larissa A. Canadeo
    6. Houda H. Harastani
    7. Tamarand L. Darling
    8. Adrianus C.M. Boon
    9. Deborah J. Lenschow
    10. Viraj Kulkarni
    11. Jon M. Huibregtse

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  4. A Fast and Accessible Method for the Isolation of RNA, DNA, and Protein To Facilitate the Detection of SARS-CoV-2

    1. Jose Carlos Ponce-Rojas
    2. Michael S. Costello
    3. Duncan A. Proctor
    4. Kenneth S. Kosik
    5. Maxwell Z. Wilson
    6. Carolina Arias
    7. Diego Acosta-Alvear

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  5. Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM

    1. Cong Xu
    2. Yanxing Wang
    3. Caixuan Liu
    4. Chao Zhang
    5. Wenyu Han
    6. Xiaoyu Hong
    7. Yifan Wang
    8. Qin Hong
    9. Shutian Wang
    10. Qiaoyu Zhao
    11. Yalei Wang
    12. Yong Yang
    13. Kaijian Chen
    14. Wei Zheng
    15. Liangliang Kong
    16. Fangfang Wang
    17. Qinyu Zuo
    18. Zhong Huang
    19. Yao Cong

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  6. SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response

    1. Jessie Huang
    2. Adam J. Hume
    3. Kristine M. Abo
    4. Rhiannon B. Werder
    5. Carlos Villacorta-Martin
    6. Konstantinos-Dionysios Alysandratos
    7. Mary Lou Beermann
    8. Chantelle Simone-Roach
    9. Jonathan Lindstrom-Vautrin
    10. Judith Olejnik
    11. Ellen L. Suder
    12. Esther Bullitt
    13. Anne Hinds
    14. Arjun Sharma
    15. Markus Bosmann
    16. Ruobing Wang
    17. Finn Hawkins
    18. Eric J. Burks
    19. Mohsan Saeed
    20. Andrew A. Wilson
    21. Elke Mühlberger
    22. Darrell N. Kotton

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  7. Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2

    1. Youngchang Kim
    2. Jacek Wower
    3. Natalia Maltseva
    4. Changsoo Chang
    5. Robert Jedrzejczak
    6. Mateusz Wilamowski
    7. Soowon Kang
    8. Vlad Nicolaescu
    9. Glenn Randall
    10. Karolina Michalska
    11. Andrzej Joachimiak

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  8. In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges

    1. Beata Turoňová
    2. Mateusz Sikora
    3. Christoph Schürmann
    4. Wim J. H. Hagen
    5. Sonja Welsch
    6. Florian E. C. Blanc
    7. Sören von Bülow
    8. Michael Gecht
    9. Katrin Bagola
    10. Cindy Hörner
    11. Ger van Zandbergen
    12. Jonathan Landry
    13. Nayara Trevisan Doimo de Azevedo
    14. Shyamal Mosalaganti
    15. Andre Schwarz
    16. Roberto Covino
    17. Michael D. Mühlebach
    18. Gerhard Hummer
    19. Jacomine Krijnse Locker
    20. Martin Beck

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  9. Elucidation of the antiviral mechanism of cystine and theanine through transcriptome analysis of mice and comparison with COVID-19 gene set data

    1. Akira Mitsui
    2. Ryosei Sakai
    3. Kiyoshi Miwa
    4. Susumu Shibahara
    5. Shigekazu Kurihara
    6. Kenji Nagao

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  10. Extremes of age are associated with differences in the expression of selected pattern recognition receptor genes and ACE2, the receptor for SARS-CoV-2: implications for the epidemiology of COVID-19 disease

    1. Stephen W. Bickler
    2. David M. Cauvi
    3. Kathleen M. Fisch
    4. James M. Prieto
    5. Alicia G. Sykes
    6. Hariharan Thangarajah
    7. David A. Lazar
    8. Romeo C. Ignacio
    9. Dale R. Gerstmann
    10. Allen F. Ryan
    11. Philip E. Bickler
    12. Antonio De Maio

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