Molecular Biology

Timing of transcription controls the selective translation of newly synthesized mRNAs during acute environmental stress

1. Mostafa Zedan
2. Alexandra P. Schürch
3. Stephanie Heinrich
4. Pablo Aurelio Gómez García
5. Sarah Khawaja
6. Léona Dörries
7. Karsten Weis

Reviewed by PREreview

The Role of Med15 Sequence Features in Transcription Factor Interactions

1. David G. Cooper
2. Shulin Liu
3. Emma Grunkemeyer
4. Jan S. Fassler

Reviewed by Review Commons

Recruitment of the m6A/m6Am demethylase FTO to target RNAs by the telomeric zinc finger protein ZBTB48

1. Syed Nabeel-Shah
2. Shuye Pu
3. Giovanni L. Burke
4. Nujhat Ahmed
5. Ulrich Braunschweig
6. Shaghayegh Farhangmehr
7. Hyunmin Lee
8. Mingkun Wu
9. Zuyao Ni
10. Hua Tang
11. Guoqing Zhong
12. Edyta Marcon
13. Zhaolei Zhang
14. Benjamin J. Blencowe
15. Jack F. Greenblatt

Reviewed by Review Commons

Dissecting translation elongation dynamics through ultra-long tracking of single ribosomes

1. Maximilian F. Madern
2. Sora Yang
3. Olivier Witteveen
4. Marianne Bauer
5. Marvin E. Tanenbaum

Reviewed by PREreview

Eugenol mimics exercise to promote skeletal muscle fiber remodeling and myokine IL-15 expression by activating TRPV1 channel

1. Tengteng Huang
2. Xiaoling Chen
3. Jun He
4. Ping Zheng
5. Yuheng Luo
6. Aimin Wu
7. Hui Yan
8. Bing Yu
9. Daiwen Chen
10. Zhiqing Huang

• Curated by eLife

  eLife assessment

  This useful paper addresses a novel exercise mimetic agent on muscle exercise and performance. While the data provided are interesting, the evidence is incomplete, as much of it is correlative.

Reviewed by eLife

The ASC inflammasome adapter controls the extent of peripheral protein aggregate deposition in inflammation-associated amyloidosis

1. Marco Losa
2. Marc Emmenegger
3. Pierre De Rossi
4. Patrick M Schürch
5. Tetiana Serdiuk
6. Niccolò Pengo
7. Danaëlle Capron
8. Dimitri Bieli
9. Niels J Rupp
10. Manfredi C Carta
11. Karl J Frontzek
12. Veronika Lysenko
13. Regina R Reimann
14. Asvin KK Lakkaraju
15. Mario Nuvolone
16. Gunilla T Westermark
17. K. Peter R. Nilsson
18. Magdalini Polymenidou
19. Alexandre P. A. Theocharides
20. Simone Hornemann
21. Paola Picotti
22. Adriano Aguzzi

Reviewed by Review Commons

Modeling the consequences of age-linked rDNA hypermethylation with dCas9-directed DNA methylation in human cells

1. Yana Blokhina
2. Abigail Buchwalter

Reviewed by Review Commons

Aberrant methylation and expression of TNXB promote chondrocyte apoptosis and extracullar matrix degradation in hemophilic arthropathy via AKT signaling

1. Jiali Chen
2. Qinghe Zeng
3. Xu Wang
4. Rui Xu
5. Weidong Wang
6. Yuliang Huang
7. Qi Sun
8. Wenhua Yuan
9. Pinger Wang
10. Di Chen
11. Peijian Tong
12. Hongting Jin

• Curated by eLife

  eLife assessment

  This important study identifies the TNXB-AKT pathway as a potential mechanism underlying hemophilia-associated cartilage degeneration. The evidence supporting the conclusions is convincing, with murine and human patient evidence as well as genome-wide DNA methylation analysis. This paper would be of interest to cell biologists and biochemists working on the field of musculoskeletal disorders.

Reviewed by eLife

Stomatin-like protein 2 senses oxidative stress through the interaction with phosphatidic acid to promote mitochondrial unfolded protein response

1. Maria Paulina Castelo Rueda
2. Irene Pichler
3. Karolina Musilova
4. Stanislav Kmoch
5. Peter P. Pramstaller
6. Ales Hnizda
7. Andrew A. Hicks
8. Roman Vozdek

Reviewed by Arcadia Science

Lipid-Based Transfection of Zebrafish Embryos: A Robust Protocol for Nucleic Acid Delivery in Zebrafish

1. Aslihan Terzi
2. Tiger Lao
3. Adrian Jacobo

Reviewed by preLights