Microbiology

  1. Gas6 drives Zika virus-induced neurological complications in humans and congenital syndrome in immunocompetent mice

    1. Joao Luiz Silva-Filho
    2. Lilian Gomes de Oliveira
    3. Leticia Monteiro
    4. Pierina L. Parise
    5. Nagela G. Zanluqui
    6. Carolina M. Polonio
    7. Carla Longo de Freitas
    8. Daniel A. Toledo-Teixeira
    9. William M. Souza
    10. Najara Bittencourt
    11. Mariene R. Amorim
    12. Julia Forato
    13. Stéfanie Primon Muraro
    14. Gabriela Fabiano de Souza
    15. Matheus Cavalheiro Martini
    16. Karina Bispos-dos-Santos
    17. Carla C. Judice
    18. Maria Laura Costa
    19. Rodrigo N. Angerami
    20. André R. R. Freitas
    21. Mariangela R. Resende
    22. Márcia T. Garcia
    23. Maria Luiza Moretti
    24. The Zika-Unicamp Network
    25. Laurent Renia
    26. Lisa F. P. Ng
    27. Carla V. Rothlin
    28. Fabio TM Costa
    29. Jean Pierre Schatzmann Peron
    30. José Luiz Proença-Modena

    • Curated by eLife

      Evaluation Summary:

      The pathophysiology of Zika virus infection remains an area of high research interest. In this study, the authors use diverse experimental models to examine the potential role of Gas6 in Zika virus infection and associated neurological sequelae.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity

  2. Nsp1 proteins of human coronaviruses HCoV-OC43 and SARS-CoV2 inhibit stress granule formation

    1. Stacia M. Dolliver
    2. Mariel Kleer
    3. Maxwell P. Bui-Marinos
    4. Shan Ying
    5. Jennifer A. Corcoran
    6. Denys A. Khaperskyy

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  3. The highly conserved stem-loop II motif is important for the lifecycle of astroviruses but dispensable for SARS-CoV-2

    1. Andrew B Janowski
    2. Hongbing Jiang
    3. Chika Fujii
    4. Macee C Owen
    5. Traci L Bricker
    6. Tamarand L Darling
    7. Houda H. Harastani
    8. Kuljeet Seehra
    9. Stephen Tahan
    10. Ana Jung
    11. Binita Febles
    12. Joshua A Blatter
    13. Scott A Handley
    14. Bijal A Parikh
    15. Valeria Lulla
    16. Adrianus CM Boon
    17. David Wang

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. A Bacteriophage-Based, Highly Efficacious, Needle- and Adjuvant-Free, Mucosal COVID-19 Vaccine

    1. Jingen Zhu
    2. Swati Jain
    3. Jian Sha
    4. Himanshu Batra
    5. Neeti Ananthaswamy
    6. Paul B. Kilgore
    7. Emily K. Hendrix
    8. Yashoda M. Hosakote
    9. Xiaorong Wu
    10. Juan P. Olano
    11. Adeyemi Kayode
    12. Cristi L. Galindo
    13. Simran Banga
    14. Aleksandra Drelich
    15. Vivian Tat
    16. Chien-Te K. Tseng
    17. Ashok K. Chopra
    18. Venigalla B. Rao

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  5. Removal of clinically relevant SARS-CoV-2 variants by an affinity resin containing Galanthus nivalis agglutinin

    1. Melanie Gooldy
    2. Christelle M. Roux
    3. Steven P. LaRosa
    4. Nicole Spaulding
    5. Charles J. Fisher

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. Structural and functional characteristics of SARS-CoV-2 Omicron subvariant BA.2 spike

    1. Jun Zhang
    2. Weichun Tang
    3. Hailong Gao
    4. Christy L. Lavine
    5. Wei Shi
    6. Hanqin Peng
    7. Haisun Zhu
    8. Krishna Anand
    9. Matina Kosikova
    10. Hyung Joon Kwon
    11. Pei Tong
    12. Avneesh Gautam
    13. Sophia Rits-Volloch
    14. Shaowei Wang
    15. Megan L. Mayer
    16. Duane R. Wesemann
    17. Michael S. Seaman
    18. Jianming Lu
    19. Tianshu Xiao
    20. Hang Xie
    21. Bing Chen

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  7. The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype

    1. G. Tuba Barut
    2. Nico Joel Halwe
    3. Adriano Taddeo
    4. Jenna N. Kelly
    5. Jacob Schön
    6. Nadine Ebert
    7. Lorenz Ulrich
    8. Christelle Devisme
    9. Silvio Steiner
    10. Bettina Salome Trüeb
    11. Bernd Hoffmann
    12. Inês Berenguer Veiga
    13. Nathan Georges François Leborgne
    14. Etori Aguiar Moreira
    15. Angele Breithaupt
    16. Claudia Wylezich
    17. Dirk Höper
    18. Kerstin Wernike
    19. Aurélie Godel
    20. Lisa Thomann
    21. Vera Flück
    22. Hanspeter Stalder
    23. Melanie Brügger
    24. Blandina I. Oliveira Esteves
    25. Beatrice Zumkehr
    26. Guillaume Beilleau
    27. Annika Kratzel
    28. Kimberly Schmied
    29. Sarah Ochsenbein
    30. Reto M. Lang
    31. Manon Wider
    32. Carlos Machahua
    33. Patrick Dorn
    34. Thomas M. Marti
    35. Manuela Funke-Chambour
    36. Andri Rauch
    37. Marek Widera
    38. Sandra Ciesek
    39. Ronald Dijkman
    40. Donata Hoffmann
    41. Marco P. Alves
    42. Charaf Benarafa
    43. Martin Beer
    44. Volker Thiel

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. P681 mutations within the polybasic motif of spike dictate fusogenicity and syncytia formation of SARS CoV-2 variants

    1. Alona Kuzmina
    2. Nofar Atari
    3. Aner Ottolenghi
    4. Dina Korovin
    5. Ido Cohen lass
    6. Benyamin Rosental
    7. Elli Rosenberg
    8. Michal Mandelboim
    9. Ran Taube

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  9. Targeted genomic sequencing with probe capture for discovery and surveillance of coronaviruses in bats

    1. Kevin S Kuchinski
    2. Kara D Loos
    3. Danae M Suchan
    4. Jennifer N Russell
    5. Ashton N Sies
    6. Charles Kumakamba
    7. Francisca Muyembe
    8. Placide Mbala Kingebeni
    9. Ipos Ngay Lukusa
    10. Frida N’Kawa
    11. Joseph Atibu Losoma
    12. Maria Makuwa
    13. Amethyst Gillis
    14. Matthew LeBreton
    15. James A Ayukekbong
    16. Nicole A Lerminiaux
    17. Corina Monagin
    18. Damien O Joly
    19. Karen Saylors
    20. Nathan D Wolfe
    21. Edward M Rubin
    22. Jean J Muyembe Tamfum
    23. Natalie A Prystajecky
    24. David J McIver
    25. Christian E Lange
    26. Andrew DS Cameron

    • Curated by eLife

      Evaluation Summary:

      This work applies hybrid-capture sequencing for coronavirus (CoV) surveillance in bats. Given that bats are a major reservoir for animal-to-human virus spillover events, which have caused several major epidemics/pandemics, this is a very important field of research. The reported hybrid-capture method shows some clear advantages over amplicon-based viral sequencing, which is the established standard in the field. This new approach has clear merits that are well supported by the data presented and is likely to become an important tool in viral surveillance programs that ultimately aim to predict/prevent/prepare for future pandemics. The work will be of interest to microbiologists, particularly those studying viruses or interested in genomics surveillance.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 agreed to share their name with the authors.)

    Reviewed by eLife, ScreenIT

    3 evaluationsAppears in 2 listsLatest version Latest activity

  10. Intrinsic furin-mediated cleavability of the spike S1/S2 site from SARS-CoV-2 variant B.1.1.529 (Omicron)

    1. Bailey Lubinski
    2. Javier A. Jaimes
    3. Gary R. Whittaker

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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