Microbiology

Microfluidic Droplet-Assisted Single-Cell Raman Sorting for High-Throughput Screening of Functional Lignin-Degrading Microbes

1. Tingting Jia
2. Manling Zhang
3. Huicheng Chen
4. Ling Lu
5. Lin Wang
6. Yunhua Wang
7. Guoxia Zheng

Reviewed by Arcadia Science

Early Pregnancy Marks Significant Shifts in the Oral Microbiome

1. Shani Finkelstein
2. Sigal Frishman
3. Sondra Turjeman
4. Oshrit Shtossel
5. Evgeny Tikhonov
6. Meital Nuriel-Ohayon
7. Yishay Pinto
8. Polina Popova
9. Alexandra S. Tkachuk
10. Elena A. Vasukova
11. Anna D. Anopova
12. Evgenii A. Pustozerov
13. Tatiana M. Pervunina
14. Elena N. Grineva
15. Moshe Hod
16. Betty Schwartz
17. Eran Hadar
18. Omry Koren
19. Yoram Louzoun

Reviewed by Arcadia Science

Stress granules formed during different RNA virus infections show remarkable plasticity and substantial virus-specific differences in their formation and composition

1. Reto M. Lang
2. Silvio Steiner
3. Jenna Kelly
4. Anne-Christine Uldry
5. Pratik Dave
6. Sophie Braga-Lagache
7. Jeffrey Chao
8. Manfred Heller
9. Volker Thiel

Reviewed by preLights

Tretinoin, a Vitamin A derivative, exerts antiviral effects against Chikungunya virus infection through the nuclear retinoid receptor signaling pathways

1. Soumyajit Ghosh
2. Chandan Mahish
3. Archana Mahapatra
4. Tathagata Mukherjee
5. Pratima Kumari
6. Bijita Bhowmick
7. Saikat De
8. Udvas Ghorai
9. Rajshree Rajmohan Jena
10. Seema Pradhan
11. Subhasis Chattopadhyay
12. Soma Chattopadhyay

Reviewed by PREreview

Ultra-deep long-read metagenomics captures diverse taxonomic and biosynthetic potential of soil microbes

1. Caner Bağcı
2. Timo Negri
3. Elena Buena Atienza
4. Caspar Gross
5. Stephan Ossowski
6. Nadine Ziemert

Reviewed by GigaScience

Research advance: Unexpected plasticity in the life cycle of Trypanosoma brucei

1. Carina Praisler
2. Jaime N Lisack
3. Anna Sophie Kreis
4. Laura Hauf
5. Johanna Krenzer
6. Fabian Imdahl
7. Markus Engstler

• Curated by eLife

  eLife Assessment

  The manuscript concerns a fundamental and controversial question in Trypanosoma brucei biology and the parasite life cycle, providing further evidence that slender bloodstream forms can indeed infect Tsetse flies. The study is solid in design and execution, and addresses several criticisms made of the authors' earlier work. Nevertheless, some of the main conclusions are only partially supported: one issue is how, precisely, a "slender" bloodstream form is defined, and discrepancies with some results from other laboratories remain unexplained.

Reviewed by eLife

From ecology to evolution: plasmid- and colicin-mediated persistence of antibiotic resistant Escherichia coli in gulls

1. Michaela Ruzickova
2. Jana Palkovicova
3. Kristina Nesporova
4. Marketa Rysava
5. Rene Pariza
6. Simon Krejci
7. Ivan Literak
8. Monika Dolejska

Reviewed by PREreview

Discovery of a potent anti-Zika virus benzamide series targeting the viral protein NS4B

1. Donghoon Chung
2. Yuka Otsuka
3. Eunjung Kim
4. Sultan Ullah
5. Nicole M. Kennedy
6. Khac Huy Ngo
7. Jinjoo Kang
8. Reece Tomlison
9. Brian Alejandro
10. Koji Barnaby
11. Jeffery Miller
12. Justin Shumate
13. Chwee Fang Teo
14. Yaw Bia Tan
15. Che Shin Chew
16. CongBao Kang
17. Dahai Luo
18. Louis Scampavia
19. Timothy P. Spicer
20. Thomas D. Bannister

Reviewed by PREreview

Environmental and Maternal Imprints on Infant Gut Metabolic Programming

1. Kine Eide Kvitne
2. Celeste Allaband
3. Jennifer C. Onuora
4. Daniela Perry
5. Simone Zuffa
6. Lucas Patel
7. Vincent Charron-Lamoureux
8. Ipsita Mohanty
9. Kristija Sejane
10. Abubaker Patan
11. Abdullah Al Mahmud
12. Tahmeed Ahmed
13. Diego G. Bassani
14. Antonio González
15. Davidson H. Hamer
16. Rashidul Haque
17. Benjamin Ho
18. Md Iqbal Hossain
19. Mohammad Shahidul Islam
20. Daniel McDonald
21. Lisa G. Pell
22. Huma Qamar
23. Daniel E. Roth
24. Samir Saha
25. Prakesh S. Shah
26. Md Muniruzzaman Siddiqui
27. Shafiqul Alam Sarker
28. Shamima Sultana
29. Sydney Thomas
30. Lindsey A. Burnett
31. Shirley M. Tsunoda
32. Lars Bode
33. Pieter C. Dorrestein
34. Rob Knight

Reviewed by preLights

Roles of the membrane-binding motif and the C-terminal domain of RNase E in localization and diffusion in E. coli

1. Laura Troyer
2. Yu-Huan Wang
3. Shobhna Shobhna
4. Seunghyeon Kim
5. Brooke Ramsey
6. Jeechul Woo
7. Emad Tajkhorshid
8. Sangjin Kim

• Curated by eLife

  eLife Assessment

  This valuable study uses single-molecule imaging to characterize factors controlling the localization, mobility, and function of RNase E in E. coli, a key bacterial ribonuclease central to mRNA catabolism. The supporting evidence for the differential roles of RNAse E's membrane targeting sequence (MTS) and the C-terminal domain (CTD) to RNAse E's diffusion and membrane association is convincing. It provides insight into how RNAse E shapes the spatiotemporal organization of RNA processing in bacterial cells. This interdisciplinary work will be of interest to cell biologists, microbiologists, biochemists, and biophysicists.

Reviewed by eLife