Immunology

A B-cell actomyosin arc network couples integrin co-stimulation to mechanical force-dependent immune synapse formation

1. Jia C Wang
2. Yang-In Yim
3. Xufeng Wu
4. Valentin Jaumouille
5. Andrew Cameron
6. Clare M Waterman
7. John H Kehrl
8. John A Hammer

• Curated by eLife

  Evaluation Summary:

  This paper is of interest to immunologists studying mechanisms of lymphocyte activation and scientists in the broader field of cell mechanics. The work provides new insight into the cooperation among receptors, the actin cytoskeleton, and myosin motors that is required for the formation of a B cell immune synapse. The data support the key claims of the manuscript.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 agreed to share their name with the authors.)

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Modulation of immunosuppressant drug treatment to improve SARS-CoV-2 vaccine efficacy in mice

1. Amy V. Paschall
2. Ahmet Ozdilek
3. Sydney L. Briner
4. Melinda A. Brindley
5. Fikri Y. Avci

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A virus-specific monocyte inflammatory phenotype is induced by SARS-CoV2 at the immune-epithelial interface

1. Juliette Leon
2. Daniel A. Michelson
3. Judith Olejnik
4. Kaitavjeet Chowdhary
5. Hyung Suk Oh
6. Adam J. Hume
7. Silvia Galván-Peña
8. Yangyang Zhu
9. Felicia Chen
10. Brinda Vijaykumar
11. Liang Yang
12. Elena Crestani
13. Lael M. Yonker
14. David M. Knipe
15. Elke Mühlberger
16. Christophe Benoist

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Protection of Hamsters Challenged with SARS-CoV-2 Variants of Concern by Two Doses of MVC-COV1901 Vaccine Followed by a Single Dose of Beta Variant Version of MVC-COV1901

1. Tsun-Yung Kuo
2. Chia-En Lien
3. Yi-Jiun Lin
4. Meei-Yun Lin
5. Chung-Chin Wu
6. Wei-Hsuan Tang
7. John D. Campbell
8. Paula Traquina
9. Ya-Shan Chuang
10. Luke Tzu-Chi Liu
11. Jinyi Cheng
12. Charles Chen

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Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody

1. Jonathan L. Torres
2. Gabriel Ozorowski
3. Emanuele Andreano
4. Hejun Liu
5. Jeffrey Copps
6. Giulia Piccini
7. Lorena Donnici
8. Matteo Conti
9. Cyril Planchais
10. Delphine Planas
11. Noemi Manganaro
12. Elisa Pantano
13. Ida Paciello
14. Piero Pileri
15. Timothée Bruel
16. Emanuele Montomoli
17. Hugo Mouquet
18. Olivier Schwartz
19. Claudia Sala
20. Raffaele De Francesco
21. Ian A. Wilson
22. Rino Rappuoli
23. Andrew B. Ward

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Durability of immune responses to the BNT162b2 mRNA vaccine

1. Mehul S. Suthar
2. Prabhu S. Arunachalam
3. Mengyun Hu
4. Noah Reis
5. Meera Trisal
6. Olivia Raeber
7. Sharon Chinthrajah
8. Meredith E. Davis-Gardner
9. Kelly Manning
10. Prakriti Mudvari
11. Eli Boritz
12. Sucheta Godbole
13. Amy R. Henry
14. Daniel C. Douek
15. Peter Halfmann
16. Yoshihiro Kawaoka
17. Scott D. Boyd
18. Mark M. Davis
19. Veronika I. Zarnitsyna
20. Kari Nadeau
21. Bali Pulendran

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SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies

1. S. Momsen Reincke
2. Meng Yuan
3. Hans-Christian Kornau
4. Victor M. Corman
5. Scott van Hoof
6. Elisa Sánchez-Sendin
7. Melanie Ramberger
8. Wenli Yu
9. Yuanzi Hua
10. Henry Tien
11. Marie Luisa Schmidt
12. Tatjana Schwarz
13. Lara Maria Jeworowski
14. Sarah E. Brandl
15. Helle Foverskov Rasmussen
16. Marie A. Homeyer
17. Laura Stöffler
18. Martin Barner
19. Désirée Kunkel
20. Shufan Huo
21. Johannes Horler
22. Niels von Wardenburg
23. Inge Kroidl
24. Tabea M. Eser
25. Andreas Wieser
26. Christof Geldmacher
27. Michael Hoelscher
28. Hannes Gänzer
29. Günter Weiss
30. Dietmar Schmitz
31. Christian Drosten
32. Harald Prüss
33. Ian A. Wilson
34. Jakob Kreye

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Use of eVLP-based vaccine candidates to broaden immunity against SARS-CoV-2 variants

1. Jasminka Bozic
2. Tanvir Ahmed
3. Barthelemy Ontsouka
4. Anne-Catherine Fluckiger
5. Abebaw Diress
6. Tamara Berthoud
7. Xiaoyang Yuan
8. Lanjian Yang
9. Francisco Diaz-Mitoma
10. David E. Anderson
11. Catalina Soare

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A combination of two human neutralizing antibodies prevents SARS-CoV-2 infection in rhesus macaques

1. Ronald R. Cobb
2. Joseph Nkolola
3. Pavlo Gilchuk
4. Abishek Chandrashekar
5. Robert V. House
6. Christopher G. Earnhart
7. Nicole M. Dorsey
8. Svetlana A. Hopkins
9. Doris M. Snow
10. Rita E. Chen
11. Laura A. VanBlargan
12. Manuel Hechenblaikner
13. Brian Hoppe
14. Laura Collins
15. Milan T. Tomic
16. Genevieve H. Nonet
17. Kyal Hackett
18. James C. Slaughter
19. Michael S. Diamond
20. Robert H. Carnahan
21. Dan H. Barouch
22. James E. Crowe

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BNT162b2 vaccination induces durable SARS-CoV-2–specific T cells with a stem cell memory phenotype

1. Gisella Guerrera
2. Mario Picozza
3. Silvia D’Orso
4. Roberta Placido
5. Marta Pirronello
6. Alice Verdiani
7. Andrea Termine
8. Carlo Fabrizio
9. Flavia Giannessi
10. Manolo Sambucci
11. Maria Pia Balice
12. Carlo Caltagirone
13. Antonino Salvia
14. Angelo Rossini
15. Luca Battistini
16. Giovanna Borsellino

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