Immunology

A large-scale systematic survey of SARS-CoV-2 antibodies reveals recurring molecular features

1. Yiquan Wang
2. Meng Yuan
3. Jian Peng
4. Ian A. Wilson
5. Nicholas C. Wu

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Potent neutralizing anti-SARS-CoV-2 human antibodies cure infection with SARS-CoV-2 variants in hamster model

1. Maya Imbrechts
2. Wim Maes
3. Louanne Ampofo
4. Nathalie Van den Berghe
5. Bas Calcoen
6. Dominique Van Looveren
7. Winnie Kerstens
8. Madina Rasulova
9. Thomas Vercruysse
10. Sam Noppen
11. Rana Abdelnabi
12. Caroline Foo
13. Kevin Hollevoet
14. Piet Maes
15. Xin Zhang
16. Dirk Jochmans
17. Karen Ven
18. Jeroen Lammertyn
19. Karen Vanhoorelbeke
20. Nico Callewaert
21. Paul De Munter
22. Dominique Schols
23. Hendrik Jan Thibaut
24. Johan Neyts
25. Paul Declerck
26. Nick Geukens

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Distinct SARS-CoV-2 sensing pathways in pDCs driving TLR7-antiviral vs. TLR2-immunopathological responses in COVID-19

1. Renée M. van der Sluis
2. Lamin B. Cham
3. Albert Gris Oliver
4. Kristine R. Gammelgaard
5. Jesper G. Pedersen
6. Manja Idorn
7. Ulvi Ahmadov
8. Sabine Sanches Hernandez
9. Ena Cémalovic
10. Stine H. Godsk
11. Jacob Thyrsted
12. Jesper D. Gunst
13. Silke D. Nielsen
14. Janni J. Jørgensen
15. Tobias Wang Bjerg
16. Anders Laustsen
17. Line S. Reinert
18. David Olagnier
19. Rasmus O. Bak
20. Mads Kjolby
21. Christian K. Holm
22. Martin Tolstrup
23. Søren R. Paludan
24. Lasse S. Kristensen
25. Ole S. Søgaard
26. Martin R. Jakobsen

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Preclinical evaluation of a COVID-19 vaccine candidate based on a recombinant RBD fusion heterodimer of SARS-CoV-2

1. Antonio Barreiro
2. Antoni Prenafeta
3. Gregori Bech-Sabat
4. Mercè Roca
5. Eva Perozo Mur
6. Ricard March
7. Luis González-González
8. Laia Madrenas
9. Júlia Corominas
10. Alex Fernández
11. Alexandra Moros
12. Manuel Cañete
13. Mercè Molas
14. Thais Pentinat-Pelegrin
15. Clara Panosa
16. Alberto Moreno
17. Ester Puigvert Molas
18. Eva Pol Vilarrassa
19. Jordi Palmada
20. Carme Garriga
21. Teresa Prat Cabañas
22. Javier Iglesias-Fernández
23. Júlia Vergara-Alert
24. Cristina Lorca-Oró
25. Núria Roca
26. Leira Fernández-Bastit
27. Jordi Rodon
28. Mònica Pérez
29. Joaquim Segalés
30. Edwards Pradenas
31. Silvia Marfil
32. Benjamin Trinité
33. Raquel Ortiz
34. Bonaventura Clotet
35. Julià Blanco
36. Jorge Díaz Pedroza
37. Rosa Ampudia Carrasco
38. Yaiza Rosales Salgado
39. Jordina Loubat-Casanovas
40. Sara Capdevila Larripa
41. Julia Garcia Prado
42. Jordi Barretina
43. Marta Sisteré-Oró
44. Paula Cebollada Rica
45. Andreas Meyerhans
46. Laura Ferrer

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Identification of a promiscuous conserved CTL epitope within the SARS-CoV-2 spike protein

1. Sheng Jiang
2. Shuting Wu
3. Gan Zhao
4. Yue He
5. Xinrong Guo
6. Zhiyu Zhang
7. Jiawang Hou
8. Yuan Ding
9. Alex Cheng
10. Bin Wang

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Resolving SARS-CoV-2 CD4+ T cell specificity via reverse epitope discovery

1. Mikhail V. Pogorelyy
2. Elisa Rosati
3. Anastasia A. Minervina
4. Robert C. Mettelman
5. Alexander Scheffold
6. Andre Franke
7. Petra Bacher
8. Paul G. Thomas

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A modified porous silicon microparticle promotes mucosal delivery of SARS-CoV-2 antigen and induction of potent and durable systemic and mucosal T helper 1 skewed protective immunity

1. Awadalkareem Adam
2. Qing Shi
3. Binbin Wang
4. Jing Zou
5. Junhua Mai
6. Samantha R Osman
7. Wenzhe Wu
8. Xuping Xie
9. Patricia V Aguilar
10. Xiaoyong Bao
11. Pei-Yong Shi
12. Haifa Shen
13. Tian Wang

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Self-assembling short immunostimulatory duplex RNAs with broad-spectrum antiviral activity

1. Longlong Si
2. Haiqing Bai
3. Crystal Yuri Oh
4. Amanda Jiang
5. Fan Hong
6. Tian Zhang
7. Yongxin Ye
8. Tristan X. Jordan
9. James Logue
10. Marisa McGrath
11. Chaitra Belgur
12. Karina Calderon
13. Atiq Nurani
14. Wuji Cao
15. Kenneth E. Carlson
16. Rachelle Prantil-Baun
17. Steven P. Gygi
18. Dong Yang
19. Colleen B. Jonsson
20. Benjamin R. tenOever
21. Matthew Frieman
22. Donald E. Ingber

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Decidual immune response following COVID-19 during pregnancy varies by timing of maternal SARS-CoV-2 infection

1. Lillian J. Juttukonda
2. Elisha M. Wachman
3. Jeffery Boateng
4. Mayuri Jain
5. Yoel Benarroch
6. Elizabeth S. Taglauer

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Widespread discrepancy in Nnt genotypes and genetic backgrounds complicates granzyme A and other knockout mouse studies

1. Daniel J Rawle
2. Thuy T Le
3. Troy Dumenil
4. Cameron Bishop
5. Kexin Yan
6. Eri Nakayama
7. Phillip I Bird
8. Andreas Suhrbier

• Curated by eLife

  Evaluation Summary:

  This paper is of interest not only for immunologists studying the inflammation, but also for biomedical researchers studying various biological processes using C57BL/6 mice. The data in this paper indicate that genetic differences between C57BL/6 substrains can affect reproducibility and generalizability in a broad range of biological studies with mouse models reported to date.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

Reviewed by eLife