1. Pandemic, Epidemic, Endemic: B Cell Repertoire Analysis Reveals Unique Anti-Viral Responses to SARS-CoV-2, Ebola and Respiratory Syncytial Virus

    This article has 23 authors:
    1. Alexander Stewart
    2. Emma Sinclair
    3. Joseph Chi-Fung Ng
    4. Joselli Silva O’Hare
    5. Audrey Page
    6. Ilaria Serangeli
    7. Christian Margreitter
    8. Federica Orsenigo
    9. Katherine Longman
    10. Cecile Frampas
    11. Catia Costa
    12. Holly-May Lewis
    13. Nora Kasar
    14. Bryan Wu
    15. David Kipling
    16. Peter JM Openshaw
    17. Christopher Chiu
    18. J Kenneth Baillie
    19. Janet T. Scott
    20. Malcolm G. Semple
    21. Melanie J. Bailey
    22. Franca Fraternali
    23. Deborah K. Dunn-Walters

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  2. T Cell Predominant Response to AAV-Spike Protects hACE2 Mice from SARS-CoV-2 Pneumonia

    This article has 22 authors:
    1. Christopher D. Greer
    2. Coral M. Kasden
    3. Leon Morales
    4. Kendall A. Lundgreen
    5. Philip D. Hicks
    6. Lilia J. Carpenter
    7. Cristhian Salas-Quinchucua
    8. Elisia D. Tichy
    9. Albert M. Maguire
    10. Jennifer G. Hoffman
    11. Robin J. Bailey
    12. Shangzhen Zhou
    13. Angela Luo
    14. Steven J. Chomistek
    15. Benjamin W. Kozyak
    16. Charles R. Bridges
    17. Gilad S. Gordon
    18. Geoffrey C. Tabin
    19. Paul F. Bates
    20. Jorge E. Osorio
    21. Jean Bennett
    22. Hansell H. Stedman

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  3. Molecular Basis of a Dominant SARS-CoV-2 Spike-Derived Epitope Presented by HLA-A*02:01 Recognised by a Public TCR

    This article has 9 authors:
    1. Christopher Szeto
    2. Andrea T. Nguyen
    3. Christian A. Lobos
    4. Demetra S. M. Chatzileontiadou
    5. Dhilshan Jayasinghe
    6. Emma J. Grant
    7. Alan Riboldi-Tunnicliffe
    8. Corey Smith
    9. Stephanie Gras

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  4. Durability of SARS-CoV-2-specific T cell responses at 12-months post-infection

    This article has 32 authors:
    1. Zhongyan Lu
    2. Eric D. Laing
    3. Jarina Pena-Damata
    4. Katherine Pohida
    5. Marana S. Tso
    6. Emily C. Samuels
    7. Nusrat J. Epsi
    8. Batsukh Dorjbal
    9. Camille Lake
    10. Stephanie A. Richard
    11. Ryan C. Maves
    12. David A. Lindholm
    13. Julia Rozman
    14. Caroline English
    15. Nikhil Huprikar
    16. Katrin Mende
    17. Rhonda E. Colombo
    18. Christopher J. Colombo
    19. Christopher C. Broder
    20. Anuradha Ganesan
    21. Charlotte A. Lanteri
    22. Brian K. Agan
    23. David Tribble
    24. Mark P. Simons
    25. Clifton L. Dalgard
    26. Paul W. Blair
    27. Josh Chenoweth
    28. Simon D. Pollett
    29. Andrew L. Snow
    30. Timothy H. Burgess
    31. Allison M.W. Malloy
    32. the EPICC COVID-19 Cohort Study Group

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  5. ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology

    This article has 24 authors:
    1. Riem Gawish
    2. Philipp Starkl
    3. Lisabeth Pimenov
    4. Anastasiya Hladik
    5. Karin Lakovits
    6. Felicitas Oberndorfer
    7. Shane JF Cronin
    8. Anna Ohradanova-Repic
    9. Gerald Wirnsberger
    10. Benedikt Agerer
    11. Lukas Endler
    12. Tümay Capraz
    13. Jan W Perthold
    14. Domagoj Cikes
    15. Rubina Koglgruber
    16. Astrid Hagelkruys
    17. Nuria Montserrat
    18. Ali Mirazimi
    19. Louis Boon
    20. Hannes Stockinger
    21. Andreas Bergthaler
    22. Chris Oostenbrink
    23. Josef M Penninger
    24. Sylvia Knapp
    This article has been curated by 1 group:
    • Curated by eLife

      Evaluation Summary:

      To establish a mouse model for the SARS-CoV-2 infection, Gawish and colleagues performed serial passage of a human virus isolate in mice. They show that the mouse-adapted SARS-CoV-2 variant remains dependent on ACE2 for efficient infection and recapitulates some clinical characteristics of COVID-19. In addition, they demonstrate that inhalation of recombinant ACE2 protected mice from mouse COVID-19 suggesting this this model will be useful for the testing of antiviral agents.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 agreed to share their name with the authors.)

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  6. Protection against SARS-CoV-2 Beta Variant in mRNA-1273 Boosted Nonhuman Primates

    This article has 65 authors:
    1. Kizzmekia S. Corbett
    2. Matthew Gagne
    3. Danielle A. Wagner
    4. Sarah O’ Connell
    5. Sandeep R. Narpala
    6. Dillon R. Flebbe
    7. Shayne F. Andrew
    8. Rachel L. Davis
    9. Barbara Flynn
    10. Timothy S. Johnston
    11. Christopher Stringham
    12. Lilin Lai
    13. Daniel Valentin
    14. Alex Van Ry
    15. Zackery Flinchbaugh
    16. Anne P. Werner
    17. Juan I. Moliva
    18. Manjari Sriparna
    19. Sijy O’Dell
    20. Stephen D. Schmidt
    21. Courtney Tucker
    22. Angela Choi
    23. Matthew Koch
    24. Kevin W. Bock
    25. Mahnaz Minai
    26. Bianca M. Nagata
    27. Gabriela S. Alvarado
    28. Amy R. Henry
    29. Farida Laboune
    30. Chaim A. Schramm
    31. Yi Zhang
    32. Lingshu Wang
    33. Misook Choe
    34. Seyhan Boyoglu-Barnum
    35. Wei Shi
    36. Evan Lamb
    37. Saule T. Nurmukhambetova
    38. Samantha J. Provost
    39. Mitzi M. Donaldson
    40. Josue Marquez
    41. John-Paul M. Todd
    42. Anthony Cook
    43. Alan Dodson
    44. Andrew Pekosz
    45. Eli Boritz
    46. Aurélie Ploquin
    47. Nicole Doria-Rose
    48. Laurent Pessaint
    49. Hanne Andersen
    50. Kathryn E. Foulds
    51. John Misasi
    52. Kai Wu
    53. Andrea Carfi
    54. Martha C. Nason
    55. John Mascola
    56. Ian N. Moore
    57. Darin K. Edwards
    58. Mark G. Lewis
    59. Mehul S. Suthar
    60. Mario Roederer
    61. Adrian McDermott
    62. Daniel C. Douek
    63. Nancy J. Sullivan
    64. Barney S. Graham
    65. Robert A. Seder

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  7. Covid-19 vaccine immunogenicity in people living with HIV-1

    This article has 12 authors:
    1. Lauriane Nault
    2. Lorie Marchitto
    3. Guillaume Goyette
    4. Daniel Tremblay-Sher
    5. Claude Fortin
    6. Valérie Martel-Laferrière
    7. Benoît Trottier
    8. Jonathan Richard
    9. Madeleine Durand
    10. Daniel Kaufmann
    11. Andrés Finzi
    12. Cécile Tremblay

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  8. Comparison of Wild Type DNA Sequence of Spike Protein from SARS-CoV-2 with Optimized Sequence on The Induction of Protective Responses Against SARS-Cov-2 Challenge in Mouse Model

    This article has 18 authors:
    1. Sheng Jiang
    2. Shuting Wu
    3. Gan Zhao
    4. Yue He
    5. Linlin Bao
    6. Jiangning Liu
    7. Chuan Qin
    8. Jiawang Hou
    9. Yuan Ding
    10. Alex Cheng
    11. Brian Jiang
    12. John Wu
    13. Jian Yan
    14. Laurent Humeau
    15. Ami Patella
    16. David B. Weiner
    17. Kate Broderick
    18. Bin Wang

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  9. Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants

    This article has 19 authors:
    1. Matthew McCallum
    2. Alexandra C. Walls
    3. Kaitlin R. Sprouse
    4. John E. Bowen
    5. Laura E. Rosen
    6. Ha V. Dang
    7. Anna De Marco
    8. Nicholas Franko
    9. Sasha W. Tilles
    10. Jennifer Logue
    11. Marcos C. Miranda
    12. Margaret Ahlrichs
    13. Lauren Carter
    14. Gyorgy Snell
    15. Matteo Samuele Pizzuto
    16. Helen Y. Chu
    17. Wesley C. Van Voorhis
    18. Davide Corti
    19. David Veesler

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  10. Optimization of Non-Coding Regions Improves Protective Efficacy of an mRNA SARS-CoV-2 Vaccine in Nonhuman Primates

    This article has 31 authors:
    1. Makda S. Gebre
    2. Susanne Rauch
    3. Nicole Roth
    4. Jingyou Yu
    5. Abishek Chandrashekar
    6. Noe B. Mercado
    7. Xuan He
    8. Jinyan Liu
    9. Katherine McMahan
    10. Amanda Martinot
    11. Tori Giffin
    12. David Hope
    13. Shivani Patel
    14. Daniel Sellers
    15. Owen Sanborn
    16. Julia Barrett
    17. Xiaowen Liu
    18. Andrew C. Cole
    19. Laurent Pessaint
    20. Daniel Valentin
    21. Zack Flinchbaugh
    22. Jake Yalley-Ogunro
    23. Jeanne Muench
    24. Renita Brown
    25. Anthony Cook
    26. Elyse Teow
    27. Hanne Andersen
    28. Mark G. Lewis
    29. Stefan O. Mueller
    30. Benjamin Petsch
    31. Dan H. Barouch

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