Immunology

Mucosal and systemic responses to SARS-CoV-2 vaccination in infection naïve and experienced individuals

1. Mohammad M. Sajadi
2. Amber Myers
3. James Logue
4. Saman Saadat
5. Narjes Shokatpour
6. James Quinn
7. Michelle Newman
8. Megan Deming
9. Zahra Rikhtegaran Tehrani
10. Maryam Karimi
11. Abdolrahim Abbasi
12. Mike Shlyak
13. Matthew B. Frieman
14. Shane Crotty
15. Anthony D. Harris

Reviewed by ScreenIT

Potential cross-protection against SARS-CoV-2 from previous exposure to bovine coronavirus

1. Lana Bazan Peters Querne
2. Fernanda Zettel Bastos
3. Breno Castello Branco Beirão

Reviewed by ScreenIT

High temporal resolution systems profiling reveals distinct patterns of interferon response after Covid-19 mRNA vaccination and SARS-CoV2 infection

1. Darawan Rinchai
2. Sara Deola
3. Gabriele Zoppoli
4. Basirudeen Syed Ahamed Kabeer
5. Sara Taleb
6. Igor Pavlovski
7. Selma Maacha
8. Giusy Gentilcore
9. Mohammed Toufiq
10. Lisa Mathew
11. Li Liu
12. Fazulur Rehaman Vempalli
13. Ghada Mubarak
14. Stephan Lorenz
15. Irene Sivieri
16. Gabriella Cirmena
17. Chiara Dentone
18. Paola Cuccarolo
19. Daniele Roberto Giacobbe
20. Federico Baldi
21. Alberto Garbarino
22. Benedetta Cigolini
23. Paolo Cremonesi
24. Michele Bedognetti
25. Alberto Ballestrero
26. Matteo Bassetti
27. Boris P. Hejblum
28. Tracy Augustine
29. Nicholas Van Panhuys
30. Rodolphe Thiebaut
31. Ricardo Branco
32. Tracey Chew
33. Maryam Shojaei
34. Kirsty Short
35. Carl Feng
36. PREDICT-19 consortium
37. Susu M. Zughaier
38. Andrea De Maria
39. Benjamin Tang
40. Ali Ait Hssain
41. Davide Bedognetti
42. Jean-Charles Grivel
43. Damien Chaussabel

Reviewed by ScreenIT

SARS-CoV-2 T cell responses are expected to remain robust against Omicron

1. Syed Faraz Ahmed
2. Ahmed Abdul Quadeer
3. Matthew R. McKay

Reviewed by ScreenIT

Th2 single-cell heterogeneity and clonal distribution at distant sites in helminth-infected mice

1. Daniel Radtke
2. Natalie Thuma
3. Christine Schülein
4. Philipp Kirchner
5. Arif B Ekici
6. Kilian Schober
7. David Voehringer

• Curated by eLife

  Evaluation Summary:

  A well written and informative study that uses scRNA-seq to examine Th2 biology in worm infections. It offers a unique angle for better defining Th2 heterogeneity and differentiation in vivo.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 and Reviewer #3 agreed to share their name with the authors.)

Reviewed by eLife

Integrative analysis of scRNA-seq and scATAC-seq revealed transit-amplifying thymic epithelial cells expressing autoimmune regulator

1. Takahisa Miyao
2. Maki Miyauchi
3. S Thomas Kelly
4. Tommy W Terooatea
5. Tatsuya Ishikawa
6. Eugene Oh
7. Sotaro Hirai
8. Kenta Horie
9. Yuki Takakura
10. Houko Ohki
11. Mio Hayama
12. Yuya Maruyama
13. Takao Seki
14. Hiroto Ishii
15. Haruka Yabukami
16. Masaki Yoshida
17. Azusa Inoue
18. Asako Sakaue-Sawano
19. Atsushi Miyawaki
20. Masafumi Muratani
21. Aki Minoda
22. Nobuko Akiyama
23. Taishin Akiyama

• Curated by eLife

  Evaluation Summary:

  The present work by Miyao and Miyauchi et al. provides new insights into the heterogeneity of mTEC. With single-cell approaches and the Fucci2a mouse model, they have found a proliferating mTEC sub-population that may be a precursor of mature mTECs expressing the Aire gene. The findings are potentially important for the field.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

Reviewed by eLife

The T cell receptor repertoire reflects the dynamics of the immune response to vaccination

1. Kevin Mohammed
2. Austin Meadows
3. Saboor Hekmaty
4. Sandra Hatem
5. Viviana Simon
6. Anitha D. Jayaprakash
7. Ravi Sachidanandam

Reviewed by ScreenIT