Immunology

  1. Simultaneous analysis of antigen‐specific B and T cells after SARS‐CoV‐2 infection and vaccination

    1. Krista L. Newell
    2. Mitchell J. Waldran
    3. Stephen J. Thomas
    4. Timothy P. Endy
    5. Adam T. Waickman

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  2. SARS-CoV-2 variants of concern remain dependent on IFITM2 for efficient replication in human lung cells

    1. Rayhane Nchioua
    2. Annika Schundner
    3. Dorota Kmiec
    4. Caterina Prelli Bozzo
    5. Fabian Zech
    6. Lennart Koepke
    7. Alexander Graf
    8. Stefan Krebs
    9. Helmut Blum
    10. Manfred Frick
    11. Konstantin M. J. Sparrer
    12. Frank Kirchhoff

    Reviewed by ScreenIT

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  3. Overriding impaired FPR chemotaxis signaling in diabetic neutrophil stimulates infection control in murine diabetic wound

    1. Ruchi Roy
    2. Janet Zayas
    3. Sunil K Singh
    4. Kaylee Delgado
    5. Stephen J Wood
    6. Mohamed F Mohamed
    7. Dulce M Frausto
    8. Yasmeen A Albalawi
    9. Thea P Price
    10. Ricardo Estupinian
    11. Eileena F Giurini
    12. Timothy M Kuzel
    13. Andrew Zloza
    14. Jochen Reiser
    15. Sasha H Shafikhani

    • Curated by eLife

      Evaluation Summary:

      This work is of interest to scientists studying pathogenesis-associated neutrophil dysfunction. Roy et al. investigated impaired wound healing associated with infected diabetic wounds, a major clinical problem. The data reveal substantial alterations in the functional competence of diabetic or glucose-exposed neutrophils to react to chemotactic signals and provide potential therapeutic strategies to improve neutrophil fitness and improve wound healing. Conclusions are supported by the data but the study, in its current stage, needs further analysis.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 agreed to share their name with the authors.)

    Reviewed by eLife

    5 evaluationsAppears in 1 listLatest version Latest activity

  4. Omicron BA.1 and BA.2 variants increase the interactions of SARS-CoV-2 spike glycoprotein with ACE2

    1. Mert Golcuk
    2. Ahmet Yildiz
    3. Mert Gur

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  5. A zebrafish model of COVID-19-associated cytokine storm syndrome reveals differential proinflammatory activities of Spike proteins of SARS-CoV-2 variants of concern

    1. Sylwia D. Tyrkalska
    2. Alicia Martínez-López
    3. Ana B. Arroyo
    4. Francisco J. Martínez-Morcillo
    5. Sergio Candel
    6. Diana García-Moreno
    7. Pablo Mesa-del-Castillo
    8. María L. Cayuela
    9. Victoriano Mulero

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. Secreted ORF8 induces monocytic pro-inflammatory cytokines through NLRP3 pathways in patients with severe COVID-19

    1. Xiaosheng Wu
    2. Michelle K. Manske
    3. Gordon J. Ruan
    4. Taylor L. Witter
    5. Kevin E. Nowakowski
    6. Jithma P. Abeykoon
    7. Xinyi Tang
    8. Yue Yu
    9. Kimberly A. Gwin
    10. Annie Wu
    11. Vanessa Taupin
    12. Vaishali Bhardwaj
    13. Jonas Paludo
    14. Surendra Dasari
    15. Haidong Dong
    16. Stephen M. Ansell
    17. Andrew D. Badley
    18. Matthew J. Schellenberg
    19. Thomas E. Witzig

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  7. Heterogeneity of neutrophils and inflammatory responses in patients with COVID-19 and healthy controls

    1. Jintao Xu
    2. Bing He
    3. Kyle Carver
    4. Debora Vanheyningen
    5. Brian Parkin
    6. Lana X. Garmire
    7. Michal A. Olszewski
    8. Jane C. Deng

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. A public antibody class recognizes an S2 epitope exposed on open conformations of SARS-CoV-2 spike

    1. Mathieu Claireaux
    2. Tom G. Caniels
    3. Marlon de Gast
    4. Julianna Han
    5. Denise Guerra
    6. Gius Kerster
    7. Barbera D. C. van Schaik
    8. Aldo Jongejan
    9. Angela I. Schriek
    10. Marloes Grobben
    11. Philip J. M. Brouwer
    12. Karlijn van der Straten
    13. Yoann Aldon
    14. Joan Capella-Pujol
    15. Jonne L. Snitselaar
    16. Wouter Olijhoek
    17. Aafke Aartse
    18. Mitch Brinkkemper
    19. Ilja Bontjer
    20. Judith A. Burger
    21. Meliawati Poniman
    22. Tom P. L. Bijl
    23. Jonathan L. Torres
    24. Jeffrey Copps
    25. Isabel Cuella Martin
    26. Steven W. de Taeye
    27. Godelieve J. de Bree
    28. Andrew B. Ward
    29. Kwinten Sliepen
    30. Antoine H. C. van Kampen
    31. Perry D. Moerland
    32. Rogier W. Sanders
    33. Marit J. van Gils

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  9. Systems immune profiling of variant-specific vaccination against SARS-CoV-2

    1. Lei Peng
    2. Jonathan J. Park
    3. Zhenhao Fang
    4. Xiaoyu Zhou
    5. Matthew B. Dong
    6. Qiancheng Xiong
    7. Chenxiang Lin
    8. Sidi Chen

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  10. Macaque-human differences in SARS-CoV-2 Spike antibody response elicited by vaccination or infection

    1. Alexandra C. Willcox
    2. Kevin Sung
    3. Meghan E. Garrett
    4. Jared G. Galloway
    5. Megan A. O’Connor
    6. Jesse H. Erasmus
    7. Jennifer K. Logue
    8. David W. Hawman
    9. Helen Y. Chu
    10. Kim J. Hasenkrug
    11. Deborah H. Fuller
    12. Frederick A. Matsen
    13. Julie Overbaugh

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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