Immunology

High Neutralizing Antibody Levels Against Severe Acute Respiratory Syndrome Coronavirus 2 Omicron BA.1 and BA.2 After UB-612 Vaccine Booster

1. Farshad Guirakhoo
2. Shixia Wang
3. Chang Yi Wang
4. Hui Kai Kuo
5. Wen Jiun Peng
6. Hope Liu
7. Lixia Wang
8. Marina Johnson
9. Adam Hunt
10. Mei Mei Hu
11. Thomas P Monath
12. Alexander Rumyantsev
13. David Goldblatt

Reviewed by ScreenIT

Persistent immune and clotting dysfunction detected in saliva and blood plasma after COVID-19

1. Hyesun Jang
2. Saibyasachi Choudhury
3. Yanbao Yu
4. Benjamin L. Sievers
5. Terri Gelbart
6. Harinder Singh
7. Stephen A. Rawlings
8. Amy Proal
9. Gene S. Tan
10. Yu Qian
11. Davey Smith
12. Marcelo Freire

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Peptidome Surveillance Across Evolving SARS-CoV-2 Lineages Reveals HLA Binding Conservation in Nucleocapsid Among Variants With Most Potential for T-Cell Epitope Loss in Spike

1. Kamil Wnuk
2. Jeremi Sudol
3. Patricia Spilman
4. Patrick Soon-Shiong

Reviewed by ScreenIT

A novel high-throughput single B-cell cloning platform for isolation and characterization of high-affinity and potent SARS-CoV-2 neutralizing antibodies

1. Paritosh Prashar
2. Sonali Swain
3. Nisha Adhikari
4. Punit Aryan
5. Anupama Singh
6. Mohit Kwatra
7. Prabhakar B

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Durable protection against SARS-CoV-2 Omicron induced by an adjuvanted subunit vaccine

1. Prabhu S. Arunachalam
2. Yupeng Feng
3. Usama Ashraf
4. Mengyun Hu
5. Venkata Viswanadh Edara
6. Veronika I. Zarnitsyna
7. Pyone Pyone Aye
8. Nadia Golden
9. Kristyn W. M. Green
10. Breanna M. Threeton
11. Nicholas J. Maness
12. Brandon J. Beddingfield
13. Rudolf P. Bohm
14. Jason Dufour
15. Kasi Russell-Lodrigue
16. Marcos C. Miranda
17. Alexandra C. Walls
18. Kenneth Rogers
19. Lisa Shirreff
20. Douglas E Ferrell
21. Nihar R. Deb Adhikary
22. Jane Fontenot
23. Alba Grifoni
24. Alessandro Sette
25. Derek T. O’Hagan
26. Robbert Van Der Most
27. Rino Rappuoli
28. Francois Villinger
29. Harry Kleanthous
30. Jay Rappaport
31. Mehul S. Suthar
32. David Veesler
33. Taia T. Wang
34. Neil P. King
35. Bali Pulendran

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COVID-19 patients have increased levels of membrane-associated and soluble CD48

1. Hadas Pahima
2. Ilan Zaffran
3. Eli Ben-Chetrit
4. Amir Jarjoui
5. Pratibha Gaur
6. Maria Laura Manca
7. Dana Reichmann
8. Efrat Orenbuch-Harroch
9. Ilaria Puxeddu
10. Carl Zinner
11. Alexandar Tzankov
12. Francesca Levi-Schaffer

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SARS-CoV-2 Omicron potently neutralized by a novel antibody with unique Spike binding properties

1. Craig Fenwick
2. Priscilla Turelli
3. Dongchun Ni
4. Laurent Perez
5. Kelvin Lau
6. Erica Lana
7. Céline Pellaton
8. Charlène Raclot
9. Line Esteves-Leuenberger
10. Jérémy Campos
11. Alex Farina
12. Flurin Fiscalini
13. Cécile Herate
14. Romain Marlin
15. Rana Abdelnabi
16. Caroline S. Foo
17. Johan Neyts
18. Pieter Leyssen
19. Roger LeGrand
20. Yves Lévy
21. Florence Pojer
22. Henning Stahlberg
23. Didier Trono
24. Giuseppe Pantaleo

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Prime-boost vaccinations with two serologically distinct chimpanzee adenovirus vectors expressing SARS-CoV-2 spike or nucleocapsid tested in a hamster COVID-19 model

1. Mohadeseh Hasanpourghadi
2. Mikhail Novikov
3. Robert Ambrose
4. Arezki Chekaoui
5. Dakota Newman
6. Jianyi Ding
7. Wynetta Giles-Davis
8. Zhiquan Xiang
9. Xiang Yang Zhou
10. Qin Liu
11. Kar Swagata
12. Hildegund CJ Ertl

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Pinpointing the tumor-specific T cells via TCR clusters

1. Mikhail M Goncharov
2. Ekaterina A Bryushkova
3. Nikita I Sharaev
4. Valeria D Skatova
5. Anastasiya M Baryshnikova
6. George V Sharonov
7. Vadim Karnaukhov
8. Maria T Vakhitova
9. Igor V Samoylenko
10. Lev V Demidov
11. Sergey Lukyanov
12. Dmitriy M Chudakov
13. Ekaterina O Serebrovskaya

• Curated by eLife

  Evaluation Summary:

  This manuscript presents a computational approach to identify T-cells which can mount an immune response against tumors. The authors examine the presence of clusters of T cells with similar sequence as a surrogate for tumor antigen specific responses. The identification of tumor-specific responses within the background of bystander T cell infiltration is an area of great current interest. This study provides solid support for the concept that T cell sequence clustering can be used to quantify the tumor specific response in vivo and in vitro.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. All reviewers agreed to share their name with the authors.)

Reviewed by eLife

T cell perturbations persist for at least 6 months following hospitalization for COVID-19

1. Melissa Govender
2. Francis R. Hopkins
3. Robin Göransson
4. Cecilia Svanberg
5. Esaki M. Shankar
6. Maria Hjorth
7. Åsa Nilsdotter-Augustinsson
8. Johanna Sjöwall
9. Sofia Nyström
10. Marie Larsson

Reviewed by ScreenIT