Immunology

Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia

1. Rogan A. Grant
2. Luisa Morales-Nebreda
3. Nikolay S. Markov
4. Suchitra Swaminathan
5. Melissa Querrey
6. Estefany R. Guzman
7. Darryl A. Abbott
8. Helen K. Donnelly
9. Alvaro Donayre
10. Isaac A. Goldberg
11. Zasu M. Klug
12. Nicole Borkowski
13. Ziyan Lu
14. Hermon Kihshen
15. Yuliya Politanska
16. Lango Sichizya
17. Mengjia Kang
18. Ali Shilatifard
19. Chao Qi
20. Jon W. Lomasney
21. A. Christine Argento
22. Jacqueline M. Kruser
23. Elizabeth S. Malsin
24. Chiagozie O. Pickens
25. Sean B. Smith
26. James M. Walter
27. Anna E. Pawlowski
28. Daniel Schneider
29. Prasanth Nannapaneni
30. Hiam Abdala-Valencia
31. Ankit Bharat
32. Cara J. Gottardi
33. G. R. Scott Budinger
34. Alexander V. Misharin
35. Benjamin D. Singer
36. Richard G. Wunderink
37. The NU SCRIPT Study Investigators
38. Rogan A. Grant
39. Luisa Morales-Nebreda
40. Nikolay S. Markov
41. Suchitra Swaminathan
42. Melissa Querrey
43. Estefany R. Guzman
44. Darryl A. Abbott
45. Helen K. Donnelly
46. Alvaro Donayre
47. Isaac A. Goldberg
48. Zasu M. Klug
49. Nicole Borkowski
50. Ziyan Lu
51. Hermon Kihshen
52. Yuliya Politanska
53. Lango Sichizya
54. Mengjia Kang
55. Ali Shilatifard
56. Chao Qi
57. Jon W. Lomasney
58. A. Christine Argento
59. Jacqueline M. Kruser
60. Elizabeth S. Malsin
61. Chiagozie O. Pickens
62. Sean B. Smith
63. James M. Walter
64. Anna E. Pawlowski
65. Daniel Schneider
66. Prasanth Nannapaneni
67. Hiam Abdala-Valencia
68. Ankit Bharat
69. Cara J. Gottardi
70. G. R. Scott Budinger
71. Alexander V. Misharin
72. Benjamin D. Singer
73. Richard G. Wunderink
74. Ajay A. Wagh
75. Alan R. Hauser
76. Alexis Rose Wolfe
77. Anjali Thakrar
78. Anjana V. Yeldandi
79. Ann A. Wang
80. Anne R. Levenson
81. Anthony M. Joudi
82. Betty Tran
83. Catherine A. Gao
84. Chitaru Kurihara
85. Clara J. Schroedl
86. Curt M. Horvath
87. Daniel Meza
88. David D. Odell
89. David W. Kamp
90. Deborah R. Winter
91. Egon A. Ozer
92. Elisheva D. Shanes
93. Elizabeth T. Bartom
94. Emily J. Rendleman
95. Emily M. Leibenguth
96. Firas Wehbe
97. Gabrielle Y. Liu
98. Gaurav T. Gadhvi
99. Heliodoro Tejedor Navarro
100. Jacob I. Sznajder
101. Jane E. Dematte
102. Jasmine Le
103. Jason M. Arnold
104. Joanne C. Du
105. John Coleman
106. Joseph I. Bailey
107. Joseph S. Deters
108. Justin A. Fiala
109. Justin Starren
110. Karen M. Ridge
111. Katharine Secunda
112. Kathleen Aren
113. Khalilah L. Gates
114. Kristy Todd
115. Lindsey D. Gradone
116. Lindsey N. Textor
117. Lisa F. Wolfe
118. Lorenzo L. Pesce
119. Luís A. Nunes Amaral
120. Madeline L. Rosenbaum
121. Manoj Kandpal
122. Manu Jain
123. Marc A. Sala
124. Mark Saine
125. Mary Carns
126. Michael J. Alexander
127. Michael J. Cuttica
128. Michelle H. Prickett
129. Nabiha H. Khan
130. Navdeep S. Chandel
131. Nicholas D. Soulakis
132. Orlyn R. Rivas
133. Patrick C. Seed
134. Paul A. Reyfman
135. Pearl D. Go
136. Peter H. S. Sporn
137. Phillip R. Cooper
138. Rade Tomic
139. Radhika Patel
140. Rafael Garza-Castillon
141. Ravi Kalhan
142. Richard I. Morimoto
143. Ruben J. Mylvaganam
144. Samuel S. Kim
145. Samuel W. M. Gatesy
146. Sanket Thakkar
147. Sarah Ben Maamar
148. SeungHye Han
149. Sharon R. Rosenberg
150. Sophia Nozick
151. Stefan J. Green
152. Susan R. Russell
153. Taylor A. Poor
154. Taylor J. Zak
155. Theresa A. Lombardo
156. Thomas Stoeger
157. Todd Shamaly
158. Ziyou Ren

Reviewed by ScreenIT

SARS-CoV-2 spike protein interacts with and activates TLR41

1. Yingchi Zhao
2. Ming Kuang
3. Junhong Li
4. Ling Zhu
5. Zijing Jia
6. Xuefei Guo
7. Yaling Hu
8. Jun Kong
9. Hang Yin
10. Xiangxi Wang
11. Fuping You

Reviewed by ScreenIT

Seroprevalence of SARS-CoV-2 specific IgG antibodies in District Srinagar, northern India – A cross-sectional study

1. S. Muhammad Salim Khan
2. Mariya Amin Qurieshi
3. Inaamul Haq
4. Sabhiya Majid
5. Arif Akbar Bhat
6. Sahila Nabi
7. Nisar Ahmad Ganai
8. Nazia Zahoor
9. Auqfeen Nisar
10. Iqra Nisar Chowdri
11. Tanzeela Bashir Qazi
12. Rafiya Kousar
13. Abdul Aziz Lone
14. Iram Sabah
15. Shahroz Nabi
16. Ishtiyaq Ahmad Sumji
17. Misbah Ferooz Kawoosa
18. Shifana Ayoub

Reviewed by ScreenIT

TCR meta-clonotypes for biomarker discovery with tcrdist3 enabled identification of public, HLA-restricted clusters of SARS-CoV-2 TCRs

1. Koshlan Mayer-Blackwell
2. Stefan Schattgen
3. Liel Cohen-Lavi
4. Jeremy C Crawford
5. Aisha Souquette
6. Jessica A Gaevert
7. Tomer Hertz
8. Paul G Thomas
9. Philip Bradley
10. Andrew Fiore-Gartland

• Curated by eLife

  Evaluation Summary:

  The paper by Mayer-Blackwell et al. builds on the idea that TCRs to the same antigen often share sequence similarities, which they quantify using a bespoke tool TCRdist3. Using this tool they develop the idea of a metaclone, a set of TCRs sharing similarities and potentially recognising the same antigen. They further show that such clonotypes show increased sharing between HLA-related individuals, and explore the use of such clonotypes in characterising antigen-specific immune response across cohorts of individuals. The paper is novel and of interest to a broad range of immunologists interested in repertoire. However, as raised in a series of detailed comments by the reviewers, the message of the paper needs to be sharpened and clearly focused on the development of the metaclone concept (with less emphasis on SARS-Cov-2. The concept of the metaclone itself, which is the main message of the paper, needs to be clarified, and characterised.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 and Reviewer #3 agreed to share their names with the authors.)

Reviewed by eLife, ScreenIT

Gamma-irradiated SARS-CoV-2 vaccine candidate, OZG-38.61.3, confers protection from SARS-CoV-2 challenge in human ACEII-transgenic mice

1. Raife Dilek Turan
2. Cihan Tastan
3. Derya Dilek Kancagi
4. Bulut Yurtsever
5. Gozde Sir Karakus
6. Samed Ozer
7. Selen Abanuz
8. Didem Cakirsoy
9. Gamze Tumentemur
10. Sevda Demir
11. Utku Seyis
12. Recai Kuzay
13. Muhammer Elek
14. Miyase Ezgi Kocaoglu
15. Gurcan Ertop
16. Serap Arbak
17. Merve Acikel Elmas
18. Cansu Hemsinlioglu
19. Ozden Hatirnaz Ng
20. Sezer Akyoney
21. Ilayda Sahin
22. Cavit Kerem Kayhan
23. Fatma Tokat
24. Gurler Akpinar
25. Murat Kasap
26. Ayse Sesin Kocagoz
27. Ugur Ozbek
28. Dilek Telci
29. Fikrettin Sahin
30. Koray Yalcin
31. Siret Ratip
32. Umit Ince
33. Ercument Ovali

Reviewed by ScreenIT

Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein

1. Naveenchandra Suryadevara
2. Swathi Shrihari
3. Pavlo Gilchuk
4. Laura A. VanBlargan
5. Elad Binshtein
6. Seth J. Zost
7. Rachel S. Nargi
8. Rachel E. Sutton
9. Emma S. Winkler
10. Elaine C. Chen
11. Mallorie E. Fouch
12. Edgar Davidson
13. Benjamin J. Doranz
14. Rita E. Chen
15. Pei-Yong Shi
16. Robert H. Carnahan
17. Larissa B. Thackray
18. Michael S. Diamond
19. James E. Crowe

Reviewed by ScreenIT

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling

1. Yi Zheng
2. Meng-Wei Zhuang
3. Lulu Han
4. Jing Zhang
5. Mei-Ling Nan
6. Peng Zhan
7. Dongwei Kang
8. Xinyong Liu
9. Chengjiang Gao
10. Pei-Hui Wang

Reviewed by ScreenIT

Reference ontology and database annotation of the COVID-19 Open Research Dataset (CORD-19)

1. Oliver Giles
2. Rachael Huntley
3. Anneli Karlsson
4. Jane Lomax
5. James Malone

Reviewed by ScreenIT

A distinct innate immune signature marks progression from mild to severe COVID-19

1. Stéphane Chevrier
2. Yves Zurbuchen
3. Carlo Cervia
4. Sarah Adamo
5. Miro E. Raeber
6. Natalie de Souza
7. Sujana Sivapatham
8. Andrea Jacobs
9. Esther Bachli
10. Alain Rudiger
11. Melina Stüssi-Helbling
12. Lars C. Huber
13. Dominik J. Schaer
14. Jakob Nilsson
15. Onur Boyman
16. Bernd Bodenmiller

Reviewed by ScreenIT

Anti-CoVid19 plasmid DNA vaccine induces a potent immune response in rodents by Pyro-drive Jet Injector intradermal inoculation

1. Tomoyuki Nishikawa
2. Chin Yang Chang
3. Jiayu A Tai
4. Hiroki Hayashi
5. Jiao Sun
6. Shiho Torii
7. Chikako Ono
8. Yoshiharu Matsuura
9. Ryoko Ide
10. Junichi Mineno
11. Miwa Sasai
12. Masahiro Yamamoto
13. Hironori Nakagami
14. Kunihiko Yamashita

Reviewed by ScreenIT