Immunology

CD4+ T cells promote fibrosis during metabolic dysfunction–associated steatohepatitis

1. Lucía Valenzuela-Pérez
2. Hyun Se Kim Lee
3. Rachel L. Bayer
4. Dina F. Manna
5. Shravan K. Mishra
6. Alexander M. Washington
7. Adna A. Hassan
8. Malaz M. Sidahmed
9. Edward Ssali
10. Ece Janet Dinc
11. Benie K. Manwana
12. Ahmed Ibrahim
13. Qianqian Guo
14. Adam Herman
15. Rondell P. Graham
16. Kevin D. Pavelko
17. Gregory J. Gores
18. Patrick Starlinger
19. Xavier S. Revelo
20. Samar H. Ibrahim
21. Enis Kostallari
22. Adebowale O. Bamidele
23. Petra Hirsova

Reviewed by PREreview

Shared Immune and Epigenetic Pathways in Systemic Lupus Erythematosus and Melanoma Immunotherapy: A Cross-Disease Analysis with Prognostic and Therapeutic Implications

1. Basma Shabana
2. Nouraldeen Ali Ramadan
3. Manar Mosad Marey
4. Mervat Mohamed Shaban

Reviewed by PREreview

The metabolic cofactor Coenzyme A enhances alternative macrophage activation via MyD88-linked signaling

1. Anthony E. Jones
2. Amy Rios
3. Neira Ibrahimovic
4. Carolina Chavez
5. Nicholas A. Bayley
6. Andréa B. Ball
7. Wei Yuan Hsieh
8. Alessandro Sammarco
9. Amber R. Bianchi
10. Angel A. Cortez
11. Thomas G. Graeber
12. Alexander Hoffmann
13. Steven J. Bensinger
14. Ajit S. Divakaruni

Reviewed by Review Commons

Label-free in-line characterization of immune cell culture using quantitative phase imaging

1. Caroline E. Serafini
2. Viswanath Gorti
3. Paloma Casteleiro Costa
4. Aaron D. Silva Trenkle
5. Bharat Kanwar
6. Bryan Wang
7. Brian Wicker
8. Linda E. Kippner
9. Isaac LeCompte
10. Rui Qi Chen
11. Benjamin Joffe
12. Ye Li
13. Annie C. Bowles-Welch
14. Jing Li
15. Christine E. Brown
16. Gabriel A. Kwong
17. Stephen Balakirsky
18. Krishnendu Roy
19. Francisco E. Robles

Reviewed by Arcadia Science

The synovial lining macrophage layer develops in the first weeks of life in a CSF1- and TGFβ-dependent but monocyte-independent process

1. Marlene Magalhaes Pinto
2. Bert Malengier-Devlies
3. Guillaume Seuzaret
4. Anna Ahlback
5. Solvig Becker
6. Katelyn Patatsos
7. Georgios Drakoulis
8. Julia Karjalainen
9. Christiane Ruedl
10. David Voehringer
11. Calum C Bain
12. Elaine Emmerson
13. Barbora Schonfeldova
14. Kristina Zec
15. Irina Udalova
16. Theodoros Simakou
17. Lucy MacDonald
18. Mariola Kurowska-Stolarska
19. Jadwiga Zarebska
20. Tonia Vincent
21. Romeo Ricci
22. Eric Erbs
23. Jack Barrington
24. Barry W McColl
25. Georgiana Neag
26. Samuel Kemble
27. Christopher Mahony
28. Adam Croft
29. Louis Boon
30. Nicole Migotsky
31. Megan L Killian
32. Oumaima Ben Brahim
33. Stefan Uderhardt
34. Alexandre Gallerand
35. Stoyan Ivanov
36. Rebecca Gentek

Reviewed by Review Commons

β-glucan reprograms macrophages to attenuate efferocytosis of cancer cells

1. Alexandros Chatzis
2. Jakub Lukaszonek
3. Dimitris Lagos
4. Dave Boucher
5. Ioannis Kourtzelis

• Curated by eLife

  eLife Assessment

  This important study describes the effect of beta-glucan innate training of macrophages and its effect on uptake of tumour cells and on the production of inflammatory cytokines. The data are convincing and show decreased phagocytic activity of apoptotic tumour cells accompanied by lower levels of secreted IL-1β, and in vivo findings are also provided in the revision. This finding has potential impact on designing potential macrophage-targeted cancer immuno-therapeutic approaches.

Reviewed by eLife